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Pan Lab: Software

 

  • An R package MinEDfind containing functions for the implementation and simulation of a Bayesian nonparametric two-stage design for minimum effective dose-finding can be downloaded from the https://cran.r-project.org/web/packages/MinEDfind/index.html. For Windows, the MinEDfind library can be downloaded from within R GUI by clicking on Packages/Install package(s), choose a mirror site, and locating MinEDfind. Questions regarding the R code, the literature, and the application of MinEDfind are welcome. An R Shiny App for this method can be found here (https://sjbiostat.shinyapps.io/mined/).
  • An R package Keyboard containing functions for the implementation and simulation of two phase I model-assisted maximum tolerated dose (MTD)-finding designs for single-agent and combination trials, and one biological dose (OBD)-finding phase I/II design. The package can be downloaded from https://cran.r-project.org/web/packages/Keyboard/index.html. R Shiny App for the single and combination trials can be found at www.trialsdesign.org.
  • An R Shiny App for Robust Bayesian model-averaging continual reassessment method (BMA-CRM) can be found at www.trialsdesign.org.

 

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