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Supplementary Information

Gene-expression patterns in drug resistant acute lymphoblastic leukemia cells and response to treatment.

Supplemental Figure 4 : Principal component analysis of drug resistant and sensitive ALL samples for the four antileukemic agents (B- and T-lineage ALL).

Figure 4

Illustrated are the top three principal components based on the significant discriminating genes for prednisolone (PRED), vincristine (VCR), asparaginase (ASP) and daunorubicin (DNR) in all 173 patients. Each sphere represents an ALL patient, labeled according to drug sensitivity (red= resistant, green= sensitive). Axes are represented in the same units as indicated by the gridlines.

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