Laboratories:
Supplemental Data:
- By Author
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- Ma, Jing, PhD
- Macdonald, Tobey
- Magdaleno, Susan
- Mahfouz, Rami
- Malkin, D.
- Mathew, Rose
- Mathew, Susan
- Mehta, Perdeep K., PhD
- Meyer, J.
- Meyling, H.
- Mikhail, Fady M.
- Miller, Christopher B.
- Mo, Bing
- Morris, Steve
- Mukatira, Suraj, PhD
- Mullighan, Charles, MBBS(Hons), MSc, MD
- Murray, Peter, PhD
- Murti, Gopal, PhD
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McCullers Lab: People
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Jon McCullers, MD Jon is a native of the Hampton Roads area of Virginia and attended the University of Virginia, graduating in 1989. While majoring in pre-med studies, his interest in virology was sparked by an emeritus professor, Dr. Rolf Benzinger. He rounded out his collegiate experience playing blues piano and specializing in the saber as Captain of the UVa fencing team. His medical studies took him on a tour of the South, where medical school and his pediatrics residency at the University of Alabama-Birmingham brought him under the tutelage of Dr. Richard Whitley. In 1996, a pediatric infectious diseases fellowship at St. Jude Children’s Research Hospital allowed study of influenza viruses under Dr. Robert Webster, and he has lived in Memphis ever since. Jon joined the infectious diseases faculty at St. Jude in 2000 and has since built an NIH funded laboratory which studies viral-bacterial synergism and novel approaches to influenza vaccination. He is currently an Associate Member in the Department of Infectious Diseases. |
| Current members of the laboratory | |
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Amy R. Iverson Amy is originally from Mississippi and received her Bachelor of Science degree from Delta State University. She joined the laboratory in 2002 and has managed our operations since 2004. Although Amy is equally facile in both viral and bacterial systems, most of her research efforts are in the area of bacterial pathogenesis. Amy studies the contribution of Streptococcus pneumoniae and Staphylococcus aureus virulence factors to synergism with influenza viruses. In addition, she is examining the role of specific immune cells in mediating clearance of bacteria from the respiratory tract and how viral infection modulates their function. |
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Irina Alymova, PhD Irina is a virologist trained at the prestigious D.I. Ivanovsky Institute of Virology in Moscow. She has more than 15 years experience working with negative strand viruses, particularly influenza and parainfluenza viruses. Her current research includes studies on the molecular basis of paramyxovirus binding, and the role of the influenza virus protein PB1-F2 in inflammation and cell death. |
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Ǻsa Karlstrom, PhD Ǻsa is originally from Stockholm, Sweden, and did her PhD work on Streptococcus equi at the Swedish University of Agriculture in Uppsala, Sweden. She moved to the United States in 2006 and joined the laboratory as a postdoctoral fellow. Her current research is on treatment of severe bacterial pneumonia. Ǻsa has made original observations on the contribution of antibiotic-mediated lysis to the inflammatory response during treatment of pneumonia and is currently evaluating different modes of therapy and probing the innate pathways and bacterial virulence factors involved in poor outcomes from severe pneumonia. |
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Nick Van De Velde, PhD Nick is from Melbourne, Australia, and received his PhD in 2008 from the MacFarlane Burnet Institute for Medical Research working on Fcgamma RII. He is exploring acute lung injury and inflammation mediated by influenza viruses. He is particularly interested in inflammatory pathways triggered by specific viral virulence factors that may alter immune recognition and responses to bacterial pathogens. |
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Nopporn Apiwattanakul, MD Nopporn received his MD and Pediatrics training in Bangkok, Thailand and joined the Pediatric Infectious Diseases Fellowship Program at St. Jude in the summer of 2008 as a postdoctoral fellow. He is exploring the impact of chronic worm infections on bacterial pneumonia using a Taenia crassiceps model. |
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Jenni Weeks, PhD Jenni arrived at St. Jude in the summer of 2009, after receiving her Ph.D. at Texas A&M and completing a special fellowship at the University of Texas. She is interested in many aspects of bacterial pathogenesis, and is currently exploring the contribution of bacterial cytotoxins to influenza virus induced inflammatory responses and secondary bacterial pneumonia. |
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Keith Wanzeck Keith is a native of Michigan, but went to school in central Tennessee. He is currently a graduate student at the University of Tennessee completing his PhD studies (on track for defense and graduation in 2009-2010). His project in the McCullers lab is to explore the impact of glycosylation of the influenza virus hemagglutinin on development of adaptive immune responses following infection or vaccination. These studies are having a major impact on our understanding of severe viral infections with the novel H1N1 swine-origin influenza virus. |
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Lee-Ann van de Velde Lee-Ann is from Melbourne, Australia, and has a background in T-cell immunogenicity studies. Her current role in the laboratory is to provide advanced immunologic support for clinical trials of influenza vaccines and influenza virus immunity. |
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Sarah Heston Sarah is a pre-med student getting laboratory experience prior to beginning her studies in Medical School. She is involved in projects examining the role of macrolide antibiotics in prevention of inflammation during treatment of pneumonia, and prevention of otitis media by live, attenuated pneumococcal vaccines. |
| Alumni of the Laboratory | |
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Julie L. McAuley, Ph.D., currently Senior Research Officer, Department of Microbiology & Immunology, University of Melbourne |
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| Former Summer and Summer Plus Students | |
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Kelly Zhang – Rhodes Summer Plus |
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