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Fischer Lab: About Us

Welcome to the lab of Marcus Fischer, PhD

Protein function often depends on flexibility and hydration. Generating structural models of these features is challenging but provides exciting opportunities for understanding biological processes and new approaches to ligand discovery. This has made structural analyses of protein function at once exciting and frustrating. Our research aims to understand how ligands, mutations, posttranslational modifications and various physical factors modulate the protein conformational landscape, and how we can use this information to impact health.

Protein function