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Supplementary Information

Microarray analysis of pneumococcal gene expression during invasive disease

Carlos J. Orihuela, Jana N. Radin, Jack E. Sublett, Geli Gao, Deepak Kaushal and Elaine I. Tuomanen

Infect Immun. 2004 Oct;72(10):5582-96.

Appendix 1. Genes marked with "X" do not meet the criteria established for microarray analysis of gene expression

Name ID Blood CSF ECC
Conserved hypothetical protein NTL02SP0067      
Transporter, truncation NTL02SP0105      
Hypothetical protein NTL02SP0107      
Conserved hypothetical protein NTL02SP0108      
Hypothetical protein NTL02SP0225      
The type 2 capsule locus of Streptococcus pneumoniae NTL02SP0315      
The type 2 capsule locus of Streptococcus pneumoniae NTL02SP0316      
The type 2 capsule locus of Streptococcus pneumoniae NTL02SP0317      
The type 2 capsule locus of Streptococcus pneumoniae NTL02SP0319      
Ribonuclease P - RNA component NTL02SP0332.1      
Hypothetical protein NTL02SP0419      
Hypothetical protein NTL02SP0491      
Hypothetical protein NTL02SP0703      
Hypothetical protein NTL02SP0955      
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase NTL02SP0961      
Conserved hypothetical protein NTL02SP0962      
Hypothetical protein NTL02SP0963      
Hypothetical protein NTL02SP0965      
Conserved hypothetical protein NTL02SP0967      
Hypothetical protein NTL02SP0968      
Nikkomycin biosynthesis protein, carboxylase NTL02SP0969      
Conserved hypothetical protein NTL02SP0970      
Conserved hypothetical protein NTL02SP0972      
Hypothetical protein NTL02SP1026      
Conserved hypothetical protein NTL02SP1178      
Cytidine deaminase NTL02SP1187      
Conserved hypothetical protein NTL02SP1188      
Hypothetical protein NTL02SP1189      
ABC transporter membrane-spanning permease NTL02SP1191      
ABC transporter substrate-binding protein NTL02SP1193      
Conserved hypothetical protein NTL02SP1194      
Hypothetical protein NTL02SP1212      
Hypothetical protein NTL02SP1402      
Hypothetical protein NTL02SP1480      
Hypothetical protein NTL02SP1483      
Hypothetical protein NTL02SP1548      
Conserved hypothetical protein NTL02SP1549      
chromosomal replication initiator protein DnaA SP0001      
DNA polymerase III, beta subunit SP0002      
hypothetical protein SP0003 X X X
GTP-binding protein SP0004      
peptidyl-tRNA hydrolase SP0005      
transcription-repair coupling factor SP0006   X  
S4 domain protein SP0007      
hypothetical protein SP0008      
hypothetical protein SP0009   X  
conserved domain protein SP0010   X  
MesJ/Ycf62 family protein SP0011      
hypoxanthine-guanine phosphoribosyltransferase SP0012      
cell division protein FtsH SP0013      
transcriptional regulator ComX1 SP0014      
IS630-Spn1, transposase Orf1 SP0015      
IS630-Spn1, transposase Orf2 SP0016      
IS1167, transposase, degenerate SP0017   X  
hypothetical protein SP0018   X  
adenylosuccinate synthetase SP0019      
cytidine/deoxycytidylate deaminase family protein SP0020   X  
deoxyuridine 5triphosphate nucleotidohydrolase, putative SP0021      
conserved hypothetical protein SP0022 X   X
DNA repair protein RadA, authentic point mutation SP0023 X   X
conserved hypothetical protein SP0024      
hypothetical protein SP0025      
hypothetical protein SP0026      
ribose-phosphate pyrophosphokinase SP0027      
IS1167, transposase, truncation SP0028 X X  
IS1167, transposase, truncation SP0028   X X
hypothetical protein SP0029 X   X
competence-induced protein Ccs16 SP0030 X   X
hypothetical protein SP0031   X  
DNA polymerase I SP0032      
conserved hypothetical protein SP0033      
membrane protein SP0034      
aromatic amino acid aminotransferase SP0035      
conserved hypothetical protein SP0036      
fatty acid/phospholipid synthesis protein PlsX SP0037      
acyl carrier protein, putative SP0038      
IS1381, transposase OrfB, truncation SP0039   X  
bacteriocin BlpU SP0041      
competence factor transporting ATP-binding/permease protein Co SP0042      
competence factor transport protein ComB SP0043      
phosphoribosylaminoimidazole-succinocarboxamide synthase SP0044   X  
phosphoribosylformylglycinamidine synthase, putative SP0045   X  
amidophosphoribosyltransferase SP0046   X  
phosphoribosylformylglycinamide cyclo-ligase SP0047   X  
phosphoribosylglycinamide formyltransferase SP0048   X  
vanZ protein, putative SP0049 X X X
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP SP0050   X  
phosphoribosylamine--glycine ligase SP0051   X  
phosphoribosylaminoimidazole carboxylase, catalytic subunit SP0053   X  
phosphoribosylaminoimidazole carboxylase, ATPase subunit SP0054      
hypothetical protein SP0055   X  
adenylosuccinate lyase SP0056      
beta-N-acetylhexosaminidase SP0057   X  
transcriptional regulator, GntR family SP0058      
beta-galactosidase SP0060 X X X
PTS system, IIB component SP0061 X X X
PTS system, IIC component SP0062 X X X
PTS system, IID component SP0063 X X X
PTS system, IIA component SP0064 X X X
sugar isomerase domain protein AgaS SP0065 X X X
aldose 1-epimerase SP0066 X X X
hypothetical protein SP0067 X X X
hypothetical protein SP0068 X X X
choline binding protein I SP0069 X X X
immunoglobulin A1 protease SP0071 X X X
conserved hypothetical protein SP0073 X X X
acetyltransferase, CysE/LacA/LpxA/NodL family SP0074 X X X
phosphorylase, Pnp/Udp family SP0075      
hypothetical protein SP0077 X X X
potassium uptake protein, Trk family SP0078      
potassium uptake protein, Trk family SP0079      
glycosyl transferase, family 2, authentic point mutation SP0081      
cell wall surface anchor family protein SP0082 X X X
DNA-binding response regulator SP0083   X  
sensor histidine kinase SP0084      
ribosomal protein S4 SP0085      
IS630-Spn1, transposase Orf1, truncation SP0086      
hypothetical protein SP0087 X X X
hypothetical protein SP0088      
ABC transporter, permease protein SP0090 X X X
ABC transporter, permease protein SP0091 X X X
ABC transporter, substrate-binding protein SP0092 X X X
hypothetical protein SP0093 X X X
hypothetical protein SP0094 X X X
conserved hypothetical protein SP0095      
hypothetical protein SP0096 X X X
conserved domain protein SP0097      
hypothetical protein SP0098      
hypothetical protein SP0099 X X X
conserved hypothetical protein SP0100 X X X
conserved hypothetical protein SP0101      
glycosyl transferase SP0102      
capsular polysaccharide biosynthesis protein, putative SP0103      
hydrolase, haloacid dehalogenase-like family SP0104      
L-serine dehydratase, iron-sulfur-dependent, alpha subunit SP0105      
L-serine dehydratase, iron-sulfur-dependent, beta subunit SP0106   X  
LysM domain protein SP0107      
hypothetical protein SP0108   X  
bacteriocin, putative SP0109 X X X
hypothetical protein SP0110   X  
amino acid ABC transporter, ATP-binding protein, putative SP0111      
amino acid ABC transporter, periplasmic amino acid-binding pro SP0112 X X X
argininosuccinate synthase, truncation SP0113   X  
hypothetical protein SP0114 X X X
hypothetical protein SP0115   X  
hypothetical protein SP0116 X X X
pneumococcal surface protein A SP0117      
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase SP0118      
MutT/nudix family protein SP0119      
glucose-inhibited division protein A SP0120      
metallo-beta-lactamase superfamily protein SP0121      
conserved hypothetical protein SP0122      
competence-induced protein Ccs1 SP0123 X X X
hypothetical protein SP0124 X X X
hypothetical protein SP0125 X X X
conserved hypothetical protein SP0127      
ribosomal-protein-alanine acetyltransferase, putative SP0128      
glycoprotease family protein SP0129      
IS1167, transposase, degenerate SP0130   X  
IS630-Spn1, transposase Orf2 SP0131   X  
IS630-Spn1, transposase Orf1, degenerate SP0132 X X X
hypothetical protein SP0133 X X X
hypothetical protein SP0134   X  
glycosyl transferase, putative SP0135   X  
glycosyl transferase, family 2 SP0136 X X X
ABC transporter, ATP-binding protein SP0137   X  
hypothetical protein SP0138 X X X
conserved domain protein SP0139 X X X
UDP-glucose 6-dehydrogenase, authentic frameshift SP0140 X X X
transcriptional regulator SP0141      
hypothetical protein SP0142   X  
conserved domain protein SP0143      
hypothetical protein SP0144      
conserved hypothetical protein SP0145   X  
conserved hypothetical protein SP0146 X X X
hypothetical protein SP0147 X X X
ABC transporter, substrate-binding protein SP0148      
lipoprotein SP0149      
peptidase, M20/M25/M40 family SP0150   X  
ABC transporter, ATP-binding protein SP0151      
ABC transporter, permease protein, putative SP0152   X  
hypothetical protein SP0153   X  
hypothetical protein SP0154      
sensor histidine kinase, putative SP0155   X  
DNA-binding response regulator SP0156      
hypothetical protein SP0157      
NrdI family protein SP0158      
conserved hypothetical protein SP0159      
conserved domain protein SP0160 X   X
conserved domain protein SP0161 X   X
transcriptional regulator PlcR, putative SP0163 X X X
hypothetical protein SP0164 X X X
flavoprotein SP0165 X X X
pyridoxal-dependent decarboxylase, Orn/Lys/Arg family SP0166 X X X
hypothetical protein SP0167 X X X
macrolide efflux protein, putative SP0168 X X X
lactose phosphotransferase system repressor, degenerate SP0169 X X X
ROK family protein SP0171 X X X
DNA mismatch repair protein HexB SP0173      
riboflavin synthase, beta subunit SP0175      
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrola SP0176      
riboflavin synthase, alpha subunit SP0177      
riboflavin biosynthesis protein RibD SP0178      
Holliday junction DNA helicase RuvA SP0179      
DNA-3-methyladenine glycosylase I SP0180   X  
conserved hypothetical protein SP0181 X X X
MccC family protein SP0182   X  
hypothetical protein SP0184      
magnesium transporter, CorA family SP0185      
excinuclease ABC, subunit A SP0186      
peptidase M24 family protein SP0187      
conserved hypothetical protein SP0189      
hypothetical protein SP0191      
conserved hypothetical protein SP0192      
conserved hypothetical protein, authentic frameshift SP0193      
conserved hypothetical protein SP0194      
dihydrofolate synthetase, putative SP0197   X  
hypothetical protein SP0198      
cardiolipin synthetase SP0199      
competence-induced protein Ccs4 SP0200      
hypothetical protein SP0201      
anaerobic ribonucleoside-triphosphate reductase SP0202      
acetyltransferase, GNAT family SP0204      
anaerobic ribonucleoside-triphosphate reductase activating pro SP0205   X  
hypothetical protein SP0206   X  
conserved domain protein SP0207   X  
ribosomal protein S10 SP0208      
ribosomal protein L3 SP0209      
ribosomal protein L4 SP0210      
ribosomal protein L23 SP0211      
ribosomal protein L2 SP0212      
ribosomal protein S19 SP0213      
ribosomal protein L22 SP0214      
ribosomal protein S3 SP0215      
ribosomal protein L16 SP0216      
ribosomal protein L29 SP0217      
ribosomal protein S17 SP0218      
ribosomal protein L14 SP0219      
ribosomal protein L24 SP0220      
ribosomal protein L5 SP0221      
ribosomal protein S14 SP0222      
ribosomal protein S8 SP0224      
ribosomal protein L6 SP0225      
ribosomal protein L18 SP0226      
ribosomal protein S5 SP0227      
ribosomal protein L30 SP0228      
ribosomal protein L15 SP0229      
preprotein translocase, SecY subunit SP0230      
adenylate kinase SP0231      
translation initiation factor IF-1 SP0232      
ribosomal protein L36 SP0233      
ribosomal protein S13 SP0234      
ribosomal protein S11 SP0235      
DNA-directed RNA polymerase, alpha subunit SP0236      
ribosomal protein L17 SP0237      
ACT domain protein SP0238      
conserved hypothetical protein SP0239      
phosphoglycerate mutase family protein SP0240      
iron ABC transporter, permease protein, degenerate SP0241 X X X
iron ABC transporter, ATP-binding protein SP0242 X X X
iron ABC transporter, iron-binding protein SP0243 X X X
pyruvate formate-lyase-activating enzyme, putative SP0245 X X X
transcriptional regulator, DeoR family SP0246   X  
transcriptional regulator SP0247 X X X
PTS system, IIA component SP0248 X X X
PTS system, IIB component SP0249 X X X
PTS system, IIC component SP0250 X X X
formate acetyltransferase, putative SP0251 X X X
transaldolase family protein SP0252 X X X
glycerol dehydrogenase SP0253 X X X
leucyl-tRNA synthetase SP0254      
acetyltransferase, GNAT family SP0255      
acetyltransferase, GNAT family SP0256   X  
group II intron, maturase, degenerate SP0257 X X X
Holliday junction DNA helicase RuvB SP0259      
conserved hypothetical protein SP0260      
undecaprenyl diphosphate synthase SP0261      
phosphatidate cytidylyltransferase SP0262   X  
eep protein SP0263      
prolyl-tRNA synthetase SP0264      
glycosyl hydrolase, family 1 SP0265      
glucosamine--fructose-6-phosphate aminotransferase, isomerizin SP0266      
oxidoreductase, putative SP0267      
alkaline amylopullulanase, putative SP0268 X X X
ribosomal protein S12 SP0271      
ribosomal protein S7 SP0272      
translation elongation factor G SP0273      
DNA polymerase III, alpha subunit, Gram-positive type SP0274      
conserved hypothetical protein SP0275   X  
conserved hypothetical protein SP0276   X  
hypothetical protein SP0277   X  
aminopeptidase PepS SP0278      
conserved hypothetical protein SP0279      
ribosomal small subunit pseudouridine synthase A SP0280      
aminopeptidase C SP0281      
PTS system, mannose-specific IID component SP0282      
PTS system, mannose-specific IIC component SP0283      
PTS system, mannose-specific IIAB components SP0284      
alcohol dehydrogenase, zinc-containing SP0285      
Cof family protein SP0286      
xanthine/uracil permease family protein SP0287      
conserved hypothetical protein SP0288   X  
dihydropteroate synthase SP0289      
dihydrofolate synthetase SP0290      
GTP cyclohydrolase I SP0291      
bifunctional folate synthesis protein SP0292      
hypothetical protein SP0293      
ribosomal protein L13 SP0294      
ribosomal protein S9 SP0295      
hypothetical protein SP0296 X X X
hypothetical protein SP0297 X X X
conserved hypothetical protein SP0298 X X X
IS630-Spn1, transposase Orf1 SP0299      
IS630-Spn1, transposase Orf2 SP0300      
conserved domain protein SP0302 X X X
6-phospho-beta-glucosidase SP0303 X X X
conserved hypothetical protein SP0304 X X X
PTS system, IIB component SP0305 X X X
transcriptional regulator, putative SP0306 X X X
PTS system, IIA component SP0307 X X X
PTS system, IIA component SP0308 X X X
hypothetical protein SP0309 X X X
PTS system, IIC component SP0310 X X X
hypothetical protein SP0311 X X X
glycosyl hydrolase, family 31 SP0312      
glutathione peroxidase SP0313 X X X
hyaluronidase SP0314 X X X
IS200S, transposase, interruption SP0315 X X X
4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluco SP0317 X X X
carbohydrate kinase, PfkB family SP0318 X X X
conserved domain protein SP0319 X X X
oxidoreductase, short chain dehydrogenase/reductase family SP0320 X X X
PTS system, IIA component SP0321 X X X
glucuronyl hydrolase SP0322 X X X
PTS system, IIB component SP0323 X X X
PTS system, IIC component SP0324 X X X
PTS system, IID component SP0325 X X X
preprotein translocase, YajC subunit SP0326 X X X
hypothetical protein, interruption SP0327 X X X
IS1380-Spn1, transposase SP0328 X X X
hypothetical protein, interruption SP0329 X X X
sugar binding transcriptional regulator RegR SP0330      
hypothetical protein, authentic frameshift SP0331 X X X
hypothetical protein SP0332 X X X
transcriptional regulator, putative SP0333 X X X
yllC protein SP0334      
cell division protein FtsL SP0335      
penicillin-binding protein 2X SP0336      
phospho-N-acetylmuramoyl-pentapeptide-transferase SP0337      
ATP-dependent Clp protease, ATP-binding subunit, putative SP0338 X   X
group II intron, maturase, truncation SP0339 X X X
autoinducer-2 production protein SP0340      
hypothetical protein SP0341      
glucan 1,6-alpha-glucosidase SP0342      
IS1380-Spn1, transposase SP0343 X X X
IS630-Spn1, transposase Orf2 SP0344      
IS630-Spn1, transposase Orf1 SP0345      
capsular polysaccharide biosynthesis protein Cps4A SP0346      
capsular polysaccharide biosynthesis protein Cps4B SP0347      
capsular polysaccharide biosynthesis protein Cps4C SP0348      
capsular polysaccharide biosynthesis protein Cps4D SP0349 X X X
capsular polysaccharide biosynthesis protein Cps4E SP0350 X X X
capsular polysaccharide biosynthesis protein Cps4F SP0351 X X X
capsular polysaccharide biosynthesis protein Cps4G SP0352 X X X
capsular polysaccharide biosynthesis protein Cps4H SP0353 X X X
hypothetical protein SP0354 X X X
hypothetical protein SP0355 X X X
O-antigen transporter RfbX, putative SP0356 X X X
UDP-N-acetylglucosamine-2-epimerase SP0357 X X X
capsular polysaccharide biosynthesis protein cps4J SP0358 X X X
capsular polysaccharide biosynthesis protein Cps4K SP0359 X X X
UDP-N-acetylglucosamine 2-epimerase SP0360 X X X
IS66 family element, Orf3, degenerate SP0362      
transposase family protein, truncation SP0363 X X X
IS66 family element, Orf2, interruption SP0364   X  
IS66 family element, Orf1, authentic frameshift SP0365 X X X
oligopeptide ABC transporter, oligopeptide-binding protein Ali SP0366      
hypothetical protein SP0367 X X X
cell wall surface anchor family protein, authentic frameshift SP0368 X X X
penicillin-binding protein 1A SP0369      
recombination protein U SP0370      
conserved hypothetical protein SP0371 X X X
conserved hypothetical protein SP0372      
conserved hypothetical protein SP0373      
hypothetical protein SP0374      
6-phosphogluconate dehydrogenase, decarboxylating SP0375      
DNA-binding response regulator SP0376      
choline binding protein C SP0377      
choline binding protein J SP0378      
conserved hypothetical protein SP0379 X X X
hypothetical protein SP0380 X X X
mevalonate kinase SP0381      
mevalonate diphosphate decarboxylase SP0382      
phosphomevalonate kinase SP0383      
FMN-dependent dehydrogenase family protein SP0384      
conserved hypothetical protein SP0385      
sensor histidine kinase, putative SP0386      
DNA-binding response regulator SP0387      
hypothetical protein, authentic frameshift SP0388      
hypothetical protein SP0389      
choline binding protein G SP0390      
choline binding protein F SP0391      
IS3-Spn1, transposase, degenerate SP0392   X  
IS3-Spn1, hypothetical protein, authentic point mutation SP0393 X X X
PTS system, mannitol-specific IIBC components SP0394 X X X
transcriptional regulator, putative SP0395 X X X
PTS system, mannitol-specific IIA component SP0396 X X X
mannitol-1-phosphate 5-dehydrogenase SP0397 X X X
hypothetical protein SP0398 X X X
glutamine ABC transporter, ATP-binding protein, truncation SP0399 X X X
trigger factor SP0400      
helicase, putative SP0401      
signal peptidase I SP0402 X X  
signal peptidase I SP0402     X
ribonuclease HIII SP0403      
hypothetical protein SP0404      
conserved hypothetical protein SP0405      
MutS2 family protein SP0406      
sodium:alanine symporter family protein SP0408      
conserved hypothetical protein SP0409 X X X
exfoliative toxin, putative SP0410   X  
seryl-tRNA synthetase SP0411      
conserved hypothetical protein SP0412      
aspartate kinase SP0413      
enoyl-CoA hydratase/isomerase family protein SP0415      
transcriptional regulator, MarR family SP0416      
3-oxoacyl-(acyl-carrier-protein) synthase III SP0417      
acyl carrier protein SP0418      
enoyl-(acyl-carrier-protein) reductase SP0419      
malonyl CoA-acyl carrier protein transacylase SP0420      
3-oxoacyl-[acyl-carrier protein] reductase SP0421      
3-oxoacyl-(acyl-carrier-protein) synthase II SP0422      
acetyl-CoA carboxylase, bitoin carboxyl carrier protein SP0423      
(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase SP0424      
acetyl-CoA carboxylase, biotin carboxylase SP0425      
acetyl-CoA carboxylase, carboxyl transferase subunit beta SP0426      
acetyl-CoA carboxylase, carboxyl transferase subunit alpha SP0427      
hypothetical protein SP0429 X X X
hypothetical protein SP0430   X  
conserved domain protein SP0431 X X X
IS1167, transposase, interruption SP0432      
N utilization substance protein B SP0433      
conserved hypothetical protein SP0434      
translation elongation factor P SP0435      
glutamyl-tRNA(Gln) amidotransferase, B subunit SP0436 X X X
glutamyl-tRNA(Gln) amidotransferase, A subunit SP0437      
glutamyl-tRNA(Gln) amidotransferase, C subunit SP0438      
peptide chain release factor 3 SP0439      
glycosyl transferase, degenerate SP0440   X  
glycosyl transferase, degenerate SP0440      
ribosomal protein L28 SP0441      
conserved hypothetical protein SP0442      
conserved hypothetical protein SP0443      
acetolactate synthase, large subunit, biosynthetic type SP0445      
acetolactate synthase, small subunit SP0446      
ketol-acid reductoisomerase SP0447      
hypothetical protein SP0448   X  
hypothetical protein SP0449      
threonine dehydratase SP0450      
hypothetical protein SP0451      
amino acid ABC transporter, ATP-binding protein SP0452      
amino acid ABC transporter, amino acid-binding protein/permeas SP0453      
hypothetical protein SP0454 X X X
hypothetical protein SP0455   X  
transposase, IS116/IS110/IS902 family, degenerate SP0456      
bacitracin resistance protein SP0457      
DNA-damage inducible protein P SP0458      
formate acetyltransferase SP0459      
IS1167, transposase SP0460 X X X
transcriptional regulator, putative SP0461 X X X
cell wall surface anchor family protein SP0462 X X X
cell wall surface anchor family protein SP0463 X X X
cell wall surface anchor family protein SP0464 X X X
hypothetical protein SP0465 X X X
sortase, putative SP0466 X X X
sortase, putative SP0467 X X X
sortase, putative SP0468 X X X
IS1167, transposase, interruption SP0469      
IS1167, transposase, interruption SP0469      
hypothetical protein SP0470 X X X
conserved hypothetical protein SP0471   X  
hypothetical protein SP0472 X X X
ROK family protein SP0473      
PTS system, cellobiose-specific IIC component SP0474 X X X
hypothetical protein SP0475 X X X
PTS system, lactose-specific IIA component SP0476 X X X
6-phospho-beta-galactosidase SP0477   X  
PTS system, lactose-specific IIBC components SP0478 X X X
potassium uptake protein, Trk family SP0479      
potassium uptake protein, Trk family SP0480      
conserved hypothetical protein SP0481      
conserved hypothetical protein SP0482      
ABC transporter, ATP-binding protein SP0483      
conserved hypothetical protein SP0484   X  
RNA methyltransferase, TrmH family SP0486 X X X
hypothetical protein SP0487   X  
conserved hypothetical protein SP0488      
PAP2 family protein SP0489      
hypothetical protein SP0490      
hypothetical protein SP0491   X  
conserved domain protein SP0492 X X X
DNA-directed RNA polymerase, delta subunit, putative SP0493      
CTP synthase SP0494      
IS1380-Spn1, transposase SP0495 X X X
Na/Pi cotransporter II-related protein SP0496      
endo-beta-N-acetylglucosaminidase, putative SP0498 X X X
phosphoglycerate kinase SP0499      
conserved domain protein SP0500   X  
transcriptional regulator, MerR family SP0501      
glutamine synthetase, type I SP0502      
hypothetical protein SP0503 X X X
type I restriction-modification system, S subunit, putative SP0505 X   X
integrase/recombinase, phage integrase family SP0506   X  
type I restriction-modification system, S subunit, putative SP0507   X  
type I restriction-modification system, S subunit SP0508      
type I restriction-modification system, M subunit SP0509      
type I restriction-modification system, R subunit SP0510   X  
hypothetical protein SP0511 X X X
hypothetical protein SP0512 X X X
hypothetical protein SP0513 X X X
hypothetical protein SP0514 X X X
heat-inducible transcription repressor HrcA SP0515      
heat shock protein GrpE SP0516      
dnaK protein SP0517      
dnaJ protein SP0519      
hypothetical protein SP0520      
HIT family protein SP0521 X X X
ABC transporter, ATP-binding protein SP0522      
ABC transporter, permease protein, putative SP0523      
BlpT protein, fusion SP0524 X X X
blpS protein SP0525      
response regulator BlpR SP0526 X X X
putative histidine kinase BlpH SP0527   X  
transport protein BlpB SP0529 X X X
BlpC ABC transporter, ATP-binding protein, authentic frameshif SP0530   X  
bacteriocin BlpI SP0531 X X X
bacteriocin BlpJ SP0532 X X X
bacteriocin BlpK SP0533      
hypothetical protein SP0535 X X X
immunity protein BlpL SP0536 X X X
IS1381, transposase OrfA SP0537   X  
IS1381, transposase OrfB SP0538      
bacteriocin BlpM SP0539 X X X
blpN protein SP0540 X X X
bacteriocin BlpO SP0541   X  
hypothetical protein SP0542 X X X
hypothetical protein SP0543 X X X
immunity protein BlpX SP0544 X X X
immunity protein BlpY SP0545 X   X
BlpZ protein, fusion SP0546 X X X
conserved domain protein SP0547 X X X
hypothetical protein SP0548 X X X
conserved hypothetical protein SP0549      
conserved hypothetical protein SP0550      
conserved hypothetical protein SP0552      
N utilization substance protein A SP0553   X  
conserved hypothetical protein SP0554      
ribosomal protein L7A family SP0555      
translation initiation factor IF-2 SP0556      
ribosome-binding factor A SP0557      
conserved hypothetical protein SP0558 X X X
hypothetical protein SP0559   X  
hypothetical protein SP0560 X X X
conserved domain protein SP0561   X  
conserved hypothetical protein SP0562      
hypothetical protein SP0563 X X X
hypothetical protein SP0564      
conserved domain protein SP0565      
acetyltransferase, GNAT family SP0566   X  
conserved domain protein SP0567 X X X
valyl-tRNA synthetase SP0568      
conserved domain protein SP0570 X X X
cell filamentation protein Fic-related protein SP0571   X  
IS1167, transposase, degenerate SP0572      
hypothetical protein SP0573 X X X
hypothetical protein SP0574 X X X
helicase, putative SP0575 X X X
transcription antiterminator Lict SP0576 X X X
PTS system, beta-glucosides-specific IIABC components SP0577 X X X
6-phospho-beta-glucosidase SP0578   X  
phenylalanyl-tRNA synthetase, alpha subunit SP0579      
acetyltransferase, GNAT family SP0580   X  
phenylalanyl-tRNA synthetase, beta subunit SP0581      
hypothetical protein SP0582      
IS1239, transposase, putative, degenerate SP0583   X  
transcriptional regulator, putative SP0584   X  
5-methyltetrahydropteroyltriglutamate--homocysteine methyltran SP0585 X X X
5,10-methylenetetrahydrofolate reductase, putative SP0586 X X X
hypothetical protein SP0587 X X X
polyribonucleotide nucleotidyltransferase SP0588      
serine acetyltransferase SP0589      
acetyltransferase, GNAT family SP0590      
cysteinyl-tRNA synthetase SP0591      
conserved hypothetical protein SP0592      
leucine-rich protein SP0593      
hypothetical protein, fusion SP0594 X X X
hypothetical protein SP0595 X X X
hypothetical protein SP0596 X X X
group II intron, maturase, degenerate SP0597   X  
group II intron, maturase, degenerate SP0597   X  
hypothetical protein SP0598 X X X
transmembrane protein Vexp1 SP0599   X  
ABC transporter, ATP-binding protein Vexp2 SP0600 X X X
transmembrane protein Vexp3 SP0601   X  
DNA-binding response regulator VncR SP0603      
sensor histidine kinase VncS SP0604      
fructose-bisphosphate aldolase SP0605      
oxidoreductase, putative SP0606      
amino acid ABC transporter, permease protein SP0607   X  
amino acid ABC transporter, permease protein SP0608   X  
amino acid ABC transporter, amino acid-binding protein SP0609   X  
amino acid ABC transporter, ATP-binding protein SP0610   X  
single-stranded-DNA-specific exonuclease RecJ SP0611      
metallo-beta-lactamase superfamily protein SP0613      
tributyrin esterase SP0614      
beta-lactam resistance factor SP0615      
beta-lactam resistance factor SP0616      
conserved domain protein SP0617      
excinuclease ABC, subunit C SP0618      
conserved hypothetical protein SP0619      
amino acid ABC transporter, amino acid-binding protein, putati SP0620   X  
nitroreductase family protein SP0622      
dipeptidase SP0623      
conserved hypothetical protein SP0624      
conserved hypothetical protein, authentic point mutation SP0625      
branched-chain amino acid transport system II carrier protein SP0626 X X X
conserved hypothetical protein SP0627      
HIT family protein SP0628      
conserved hypothetical protein SP0629      
ribosomal protein L11 SP0630      
ribosomal protein L1 SP0631      
group II intron, maturase, truncation SP0632   X  
hypothetical protein SP0633 X X X
conserved domain protein SP0634 X X X
hypothetical protein SP0635      
ABC transporter, ATP-binding protein SP0636      
membrane protein SP0637   X  
conserved hypothetical protein SP0638      
hypothetical protein SP0639      
hypothetical protein SP0640   X  
serine protease, subtilase family SP0641      
IS1167, transposase, truncation SP0642 X X  
IS1167, transposase, truncation SP0642     X
transposase family protein, truncation SP0643   X  
IS66 family element, Orf3, degenerate SP0644      
PTS system IIA component, putative SP0645 X X X
PTS system, IIB component, putative SP0646 X X X
PTS system, IIC component, putative SP0647 X X X
beta-galactosidase SP0648 X X X
conserved hypothetical protein, degenerate SP0649 X X X
hypothetical protein SP0650   X  
conserved hypothetical protein SP0651   X  
conserved hypothetical protein SP0652      
hypothetical protein SP0653 X X X
sodium/hydrogen exchanger family protein SP0655   X  
hypothetical protein SP0656   X  
ribonuclease BN, putative SP0657   X  
cytochrome c-type biogenesis protein CcdA SP0658 X X  
cytochrome c-type biogenesis protein CcdA SP0658   X X
thioredoxin family protein SP0659 X X  
thioredoxin family protein SP0659   X X
peptide methionine sulfoxide reductase SP0660 X X X
DNA-binding response regulator SP0661   X  
sensor histidine kinase, putative SP0662   X  
conserved hypothetical protein SP0663      
zinc metalloprotease ZmpB, putative SP0664 X X X
chorismate binding enzyme SP0665   X  
conserved hypothetical protein SP0666 X X X
pneumococcal surface protein, putative SP0667      
glucokinase SP0668      
thymidylate synthase SP0669      
hypothetical protein SP0670      
tRNA isopentenylpyrophosphate transferase SP0671      
GTP-binding protein HflX SP0672      
hypothetical protein SP0673      
metallo-beta-lactamase superfamily protein SP0674      
oxidoreductase, short chain dehydrogenase/reductase family SP0675      
transcriptional regulator, putative SP0676      
conserved hypothetical protein SP0677      
conserved hypothetical protein SP0678      
hypothetical protein SP0679 X X X
ribosomal small subunit pseudouridine synthase A SP0680 X X X
elongation factor Tu family protein SP0681      
hypothetical protein SP0682   X  
conserved hypothetical protein SP0686   X  
ABC transporter, ATP-binding protein SP0687 X X X
UDP-N-acetylmuramoylalanine--D-glutamate ligase SP0688      
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyroph SP0689      
cell division protein DivIB SP0690      
hypothetical protein SP0691   X  
hypothetical protein SP0692 X X X
conserved domain protein SP0694   X  
HesA/MoeB/ThiF family protein SP0695   X  
hypothetical protein SP0696 X X X
ABC transporter, ATP-binding protein, authentic point mutation SP0697 X X X
hypothetical protein SP0698 X X X
transposase, IS30 family, degenerate SP0700   X  
orotidine 5-phosphate decarboxylase SP0701 X X X
orotate phosphoribosyltransferase PyrE SP0702   X  
hypothetical protein SP0703   X  
hypothetical protein SP0704 X X X
hypothetical protein SP0705   X  
hypothetical protein SP0706 X X X
ABC transporter, ATP-binding protein SP0707   X  
amino acid ABC transporter, amino acid-binding protein, authen SP0708 X X X
amino acid ABC transporter, ATP-binding protein SP0709 X X X
amino acid ABC transporter, permease protein SP0710   X  
amino acid ABC transporter, permease protein SP0711 X X X
lactate oxidase, truncation SP0712      
lysyl-tRNA synthetase SP0713      
IS1380-Spn1, transposase SP0714 X X X
lactate oxidase SP0715      
transcriptional regulator, putative SP0716      
hydroxyethylthiazole kinase SP0717      
thiamine-phosphate pyrophosphorylase SP0718 X X X
conserved hypothetical protein SP0719 X X X
ABC transporter, ATP-binding protein SP0720 X X X
conserved hypothetical protein SP0721 X X X
transcriptional activator TenA SP0722 X X X
conserved domain protein SP0723 X X X
hydroxyethylthiazole kinase, putative SP0724 X X X
thiamine-phosphate pyrophosphorylase SP0725 X X X
phosphomethylpyrimidine kinase SP0726 X X X
transcriptional repressor, putative SP0727 X X X
hypothetical protein SP0728      
cation-transporting ATPase, E1-E2 family SP0729      
pyruvate oxidase SP0730      
conserved domain protein SP0731      
transposase family protein, authentic frameshift SP0732 X X X
hypothetical protein SP0733 X X X
6-phospho-beta-glucosidase, truncation SP0735 X X X
mannose-6-phosphate isomerase SP0736      
sodium-dependent transporter SP0737 X X X
conserved domain protein SP0738 X X X
transcriptional regulator, MerR family SP0739   X  
MutT/nudix family protein SP0740   X  
conserved hypothetical protein SP0741      
conserved hypothetical protein SP0742      
transcriptional regulator, TetR family SP0743   X  
cytidine and deoxycytidylate deaminase family protein SP0744   X  
uracil phosphoribosyltransferase SP0745      
ATP-dependent Clp protease, proteolytic subunit SP0746      
conserved hypothetical protein SP0748   X  
branched-chain amino acid ABC transporter, amino acid-binding SP0749      
branched-chain amino acid ABC transporter, permease protein SP0750      
branched-chain amino acid ABC transporter, permease protein SP0751      
branched-chain amino acid ABC transporter, ATP-binding protein SP0752      
branched-chain amino acid ABC transporter, ATP-binding protein SP0753      
acetoin utilization protein AcuB, putative SP0754 X X X
peptide chain release factor 2, authentic frameshift SP0755      
cell division ABC transporter, ATP-binding protein FtsE SP0756      
cell division ABC transporter, permease protein FtsX SP0757      
PTS system, IIABC components SP0758   X  
hypothetical protein SP0759 X X X
hypothetical protein SP0760 X X X
ATP-dependent RNA helicase, DEAD/DEAH box family SP0761   X  
S-adenosylmethionine synthetase SP0762      
hypothetical protein SP0763 X X X
dihydroorotate dehydrogenase A SP0764      
conserved hypothetical protein SP0765      
superoxide dismutase, manganese-dependent SP0766      
conserved hypothetical protein SP0767      
conserved hypothetical protein SP0768      
VanZF-related protein SP0769      
ABC transporter, ATP-binding protein SP0770      
peptidyl-prolyl cis-trans isomerase, cyclophilin-type SP0771      
hypothetical protein SP0772 X X X
hypothetical protein SP0774 X X X
ribosomal protein S16 SP0775      
KH domain protein SP0776      
hypothetical protein SP0777      
16S rRNA processing protein RimM SP0778      
tRNA (guanine-N1)-methyltransferase SP0779      
ribonucleoside-diphosphate reductase, alpha subunit, truncatio SP0780      
hypothetical protein SP0781      
conserved hypothetical protein SP0782 X X X
conserved hypothetical protein SP0783      
glutathione reductase SP0784      
conserved hypothetical protein SP0785      
ABC transporter, ATP-binding protein SP0786      
conserved hypothetical protein SP0787      
methionyl-tRNA synthetase SP0788      
conserved hypothetical protein SP0789   X  
conserved domain protein SP0790   X  
oxidoreductase, aldo/keto reductase family SP0791      
hypothetical protein SP0792      
oxidoreductase, short chain dehydrogenase/reductase family SP0793      
MutT/nudix family protein SP0794      
PEP-utilizing enzymes family protein SP0795   X  
conserved hypothetical protein SP0796   X  
aminopeptidase N SP0797      
DNA-binding response regulator CiaR SP0798      
sensor histidine kinase CiaH SP0799      
hypothetical protein SP0800      
conserved hypothetical protein SP0801      
DNA polymerase III, epsilon subunit/ATP-dependent helicase Din SP0802      
rod shape-determining protein RodA, putative SP0803      
4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis SP0804      
hydrolase, haloacid dehalogenase-like family SP0805      
DNA gyrase subunit B SP0806      
septation ring formation regulator EzrA, putative SP0807      
hypothetical protein SP0810 X X X
transposase family protein SP0811 X X X
IS66 family element, Orf2, interruption SP0812      
IS3-Spn1, hypothetical protein, authentic point mutation SP0813   X  
IS3-Spn1, transposase, internal deletion SP0814 X X X
hypothetical protein SP0816      
MutT/nudix family protein SP0817 X X X
IS630-Spn1, transposase Orf1 SP0818      
IS630-Spn1, transposase Orf2 SP0819      
ATP-dependent Clp protease, ATP-binding subunit ClpE SP0820      
conserved hypothetical protein SP0822      
amino acid ABC transporter, permease protein SP0823 X X X
amino acid ABC transporter, ATP-binding protein SP0824   X  
methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofola SP0825      
hypothetical protein SP0826 X X X
conserved hypothetical protein, authentic point mutation SP0827 X X X
ribose 5-phosphate isomerase SP0828      
phosphopentomutase SP0829      
hypothetical protein SP0830      
purine nucleoside phosphorylase, family 2 SP0831      
hypothetical protein SP0832   X  
hypothetical protein SP0833      
hemolysin-related protein SP0834      
purine nucleoside phosphorylase, family 1 SP0835      
IS1167, transposase SP0836      
IS1167, transposase SP0836      
DNA topology modulation protein FlaR, putative SP0837      
ribosomal protein S20 SP0838      
pantothenate kinase SP0839      
hypothetical protein SP0840 X X X
conserved hypothetical protein SP0841      
pyrimidine-nucleoside phosphorylase SP0842      
deoxyribose-phosphate aldolase SP0843      
cytidine deaminase SP0844      
lipoprotein SP0845      
sugar ABC transporter, ATP-binding protein SP0846      
sugar ABC transporter, permease protein, putative SP0847      
sugar ABC transporter, permease protein, putative SP0848      
IS3-Spn1, hypothetical protein, degenerate SP0849 X X X
IS3-Spn1, transposase, authentic point mutation SP0850   X  
conserved hypothetical protein SP0851   X  
topoisomerase IV, subunit B SP0852   X  
hypothetical protein SP0854 X X X
topoisomerase IV, subunit A SP0855   X  
branched-chain amino acid aminotransferase SP0856      
oligopeptide-binding protein, internal deletion, authentic poi SP0857      
membrane protein, putative SP0858      
membrane protein SP0859      
pyrrolidone-carboxylate peptidase SP0860      
hypothetical protein SP0861      
ribosomal protein S1 SP0862      
IS1167, transposase, degenerate SP0863      
conserved hypothetical protein SP0864      
DNA polymerase III, gamma and tau subunits SP0865      
hypothetical protein SP0866      
ABC transporter, ATP-binding protein SP0867      
conserved hypothetical protein SP0868      
aminotransferase, class-V SP0869      
NifU family protein SP0870      
conserved hypothetical protein SP0871      
D-alanyl-D-alanine carboxypeptidase SP0872      
membrane protein SP0873      
lactose phosphotransferase system repressor SP0875      
1-phosphofructokinase, putative SP0876      
PTS system, fructose specific IIABC components SP0877   X  
spoE family protein SP0878      
hypothetical protein SP0879 X   X
aminotransferase, class-V SP0880      
thiazole biosynthesis protein ThiI SP0881      
conserved hypothetical protein SP0882 X X X
hypothetical protein SP0883 X X X
hypothetical protein SP0884 X X X
hypothetical protein SP0885   X  
type I restriction-modification system, M subunit, putative SP0886      
type I restriction-modification system, S subunit, putative SP0887      
hypothetical protein SP0888 X X X
hypothetical protein SP0889 X X X
integrase/recombinase, phage integrase family SP0890 X X X
type I restriction-modification system, S subunit, putative SP0891 X X X
type I restriction-modification system, R subunit, putative SP0892      
transcriptional repressor, putative SP0893 X X X
X-pro dipeptidyl-peptidase SP0894 X X X
DNA polymerase III, alpha subunit SP0895   X  
6-phosphofructokinase SP0896      
pyruvate kinase SP0897      
transcriptional repressor, degenerate SP0898   X  
conserved hypothetical protein SP0899   X  
IS1381, transposase OrfA, truncation SP0900 X X X
hypothetical protein SP0901   X  
hypothetical protein SP0902 X X X
hypothetical protein SP0903 X X X
conserved hypothetical protein SP0904      
conserved hypothetical protein SP0905      
capsular polysaccharide biosynthesis protein, putative SP0907 X X X
transcriptional regulator, putative SP0908      
conserved hypothetical protein SP0909   X  
conserved hypothetical protein SP0910      
hypothetical protein SP0911 X X X
ABC transporter, ATP-binding protein SP0912 X X X
ABC transporter, permease protein, putative SP0913 X X X
nodulin-related protein, truncation SP0914 X X X
IS1239, transposase, putative SP0915 X X X
lysine decarboxylase SP0916   X  
pilin gene inverting-related protein SP0917      
SPermidine synthase SP0918      
conserved hypothetical protein SP0919   X  
carboxynorspermidine decarboxylase SP0920   X  
conserved hypothetical protein SP0921      
carbon-nitrogen hydrolase family protein SP0922      
Cof family protein SP0923 X X X
hypothetical protein SP0924 X X X
conserved hypothetical protein SP0925   X  
hypothetical protein SP0926 X X X
transcriptional regulator, LysR family SP0927      
lipoprotein signal peptidase SP0928      
ribosomal large subunit pseudouridine synthase D SP0929   X  
choline binding protein E SP0930      
glutamate 5-kinase SP0931      
gamma-glutamyl phosphate reductase SP0932      
pyrroline-5-carboxylate reductase SP0933   X  
thymidylate kinase SP0935      
DNA polymerase III, delta prime subunit SP0936      
conserved hypothetical protein SP0937   X  
tetrapyrrole methylase family protein SP0938      
conserved hypothetical protein SP0939   X  
replication initiator protein, truncation, authentic frameshif SP0940 X X X
IS1381, transposase OrfB SP0941      
IS1381, transposase OrfA SP0942   X  
Gid protein SP0943      
uridylate kinase SP0944      
ribosome recycling factor SP0945      
conserved hypothetical protein SP0946 X   X
conserved hypothetical protein SP0947   X  
PhoH family protein SP0948      
IS1515, transposase, authentic frameshift SP0949 X X X
acetyltransferase, GNAT family SP0950      
conserved hypothetical protein SP0951      
alanine dehydrogenase, authentic frameshift SP0952   X  
acetyltransferase, GNAT family SP0953 X X X
competence protein CelA SP0954 X X X
competence protein CelB SP0955 X X X
hypothetical protein SP0956      
ABC transporter, ATP-binding protein SP0957 X X X
hypothetical protein SP0958      
translation initiation factor IF-3 SP0959      
ribosomal protein L35 SP0960      
ribosomal protein L20 SP0961      
lactoylglutathione lyase SP0962      
dihydroorotate dehydrogenase, electron transfer subunit SP0963      
dihydroorotate dehydrogenase B SP0964      
endo-beta-N-acetylglucosaminidase SP0965      
adherence and virulence protein A SP0966      
conserved hypothetical protein TIGR00043 SP0967      
diacylglycerol kinase SP0968 X X X
GTP-binding protein Era SP0969      
formamidopyrimidine-DNA glycosylase SP0970      
kinase, putative SP0971      
multi-drug resistance efflux pump SP0972      
ribosomal protein L33 SP0973   X  
preprotein translocase, SecG subunit, putative SP0974      
exoribonuclease, VacB/Rnb family SP0975      
SsrA-binding protein SP0976      
tellurite resistance protein TehB SP0977 X X  
tellurite resistance protein TehB SP0977     X
competence protein CoiA SP0978 X X X
oligoendopeptidase F SP0979      
O-methyltransferase SP0980      
protease maturation protein, putative SP0981      
IS3-Spn1, hypothetical protein/transposase, internal deletion SP0982 X X X
IS630-Spn1, transposase Orf2, degenerate SP0983 X X X
phosphoglycerate mutase family protein SP0984   X  
regulatory protein, putative SP0985   X  
conserved hypothetical protein SP0986   X  
hypothetical protein SP0987      
UDP-N-acetylglucosamine pyrophosphorylase SP0988      
MutT/nudix family protein SP0989      
hypothetical protein SP0990      
5-methylthioadenosine/S-adenosylhomocysteine nucleosidase SP0991      
conserved hypothetical protein SP0992      
exonuclease SP0993      
hypothetical protein SP0994      
IS630-Spn1, transposase Orf1 SP0995      
IS630-Spn1, transposase Orf2, truncation SP0996      
hypothetical protein SP0997 X X X
hypothetical protein SP0998 X X X
cytochrome c-type biogenesis protein CcdA SP0999 X X X
thioredoxin family protein SP1000      
amino acid permease family protein SP1001      
adhesion lipoprotein SP1002      
conserved hypothetical protein SP1003      
conserved hypothetical protein SP1004 X X X
conserved domain protein, degenerate SP1005 X X X
hypothetical protein SP1006 X X X
hypothetical protein SP1007 X X X
peptidase t SP1008      
ferrochelatase SP1009 X X X
large conductance mechanosensitive channel protein MscL SP1010      
GtrA family protein SP1011 X X X
conserved hypothetical protein SP1012   X  
aspartate-semialdehyde dehydrogenase SP1013      
dihydrodipicolinate synthase SP1014      
IS1167, transposase, authentic frameshift SP1015      
IS1167, transposase, authentic frameshift SP1015      
thiophene and furan oxidation protein ThdF SP1016      
4-oxalocrotonate tautomerase SP1017      
thymidine kinase SP1018      
acetyltransferase, GNAT family SP1019      
peptide chain release factor 1 SP1020      
HemK protein SP1021      
Sua5/YciO/YrdC family protein SP1022      
acetyltransferase, GNAT family SP1023      
serine hydroxymethyltransferase SP1024      
hypothetical protein SP1025   X  
conserved hypothetical protein SP1026      
conserved hypothetical protein SP1027      
RNA methyltransferase, TrmA family SP1029      
conserved hypothetical protein SP1030 X X X
iron-compound ABC transporter, iron compound-binding protein SP1032      
iron-compound ABC transporter, permease protein SP1033   X  
iron-compound ABC transporter, permease protein SP1034   X  
iron-compound ABC transporter, ATP-binding protein SP1035   X  
type II restriction endonuclease, putative SP1037 X X X
hypothetical protein SP1038 X X X
hypothetical protein SP1039 X X X
site-specific recombinase, resolvase family SP1040   X  
hypothetical protein SP1041 X X X
hypothetical protein SP1042 X X X
hypothetical protein SP1043   X  
hydrolase, putative SP1044   X  
conserved hypothetical protein TIGR00147 SP1045      
alpha amylase family protein, authentic point mutation SP1046 X X X
hypothetical protein SP1047 X X X
hypothetical protein SP1048 X X X
hypothetical protein SP1049 X X X
transcriptional regulator, putative SP1050 X X X
conserved hypothetical protein SP1051   X  
phosphoesterase, putative SP1052   X  
conserved domain protein SP1053   X  
Tn5252, Orf 10 protein SP1054 X X X
Tn5252, Orf 9 protein SP1055 X X X
Tn5252, relaxase SP1056 X X X
transcriptional regulator PlcR, putative SP1057 X X X
hypothetical protein SP1058 X X X
hypothetical protein SP1059 X X X
hypothetical protein SP1060 X X X
protein kinase, putative SP1061 X X X
ABC transporter, ATP-binding protein SP1062 X X X
ABC-2 transporter, permease protein, putative SP1063 X X X
transposase, IS200 family SP1064 X X X
hypothetical protein SP1065 X X X
IS1381, transposase OrfA, truncation SP1066 X X X
cell division protein FtsW, putative SP1067      
phosphoenolpyruvate carboxylase SP1068      
conserved hypothetical protein SP1069   X  
conserved hypothetical protein SP1070      
ABC transporter, ATP-binding protein SP1071      
DNA primase SP1072      
RNA polymerase sigma-70 factor SP1073      
conserved hypothetical protein SP1074      
glycosyl transferase CpoA SP1075      
glycosyl transferase, group 1 SP1076      
conserved domain protein SP1077   X  
hypothetical protein SP1078 X X X
GTP-binding protein, GTP1/Obg family SP1079      
hypothetical protein SP1080   X  
UDP-N-acetylglucosamine 1-carboxyvinyltransferase SP1081      
acetyltransferase, GNAT family SP1082      
conserved hypothetical protein SP1083      
methionine aminopeptidase, type I SP1084      
IS1381, transposase OrfA, authentic frameshift SP1085   X  
IS1381, transposase OrfB SP1086      
ATP-dependent DNA helicase PcrA SP1087      
DNA repair protein RadC SP1088      
glutamine amidotransferase, class I SP1089   X  
conserved hypothetical protein SP1090      
hypothetical protein SP1092   X  
hypothetical protein SP1093   X  
aminotransferase, class-V SP1094      
ribose-phosphate pyrophosphokinase SP1095      
conserved hypothetical protein SP1096 X X X
conserved hypothetical protein SP1097 X   X
conserved hypothetical protein SP1098      
ribosomal large subunit pseudouridine synthase, RluD subfamily SP1099      
phosphate acetyltransferase SP1100      
IS1167, transposase, degenerate SP1101      
conserved hypothetical protein TIGR00103 SP1102   X  
hypothetical protein SP1104      
ribosomal protein L21 SP1105      
conserved hypothetical protein SP1106      
ribosomal protein L27 SP1107      
hypothetical protein SP1108 X X X
hypothetical protein SP1109 X X X
macrolide-efflux protein SP1110      
conserved hypothetical protein SP1111      
degV family protein SP1112      
DNA-binding protein HU SP1113      
ABC transporter, ATP-binding protein SP1114   X  
ABC transporter, ATP-binding protein SP1114   X  
transcriptional regulator MutR, putative SP1115   X  
transporter, putative SP1116   X  
DNA ligase, NAD-dependent SP1117   X  
pullulanase, putative SP1118      
glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent SP1119   X  
1,4-alpha-glucan branching enzyme SP1121 X X X
glucose-1-phosphate adenylyltransferase SP1122      
glycogen biosynthesis protein GlgD SP1123   X  
glycogen synthase SP1124   X  
phosphoserine phosphatase SerB, degenerate SP1125 X X X
conserved hypothetical protein TIGR00045 SP1126 X X X
hypothetical protein SP1127   X  
enolase SP1128      
integrase/recombinase, phage integrase family SP1129 X X X
transcriptional regulator SP1130 X X X
transcriptional regulator, putative SP1131 X X X
hypothetical protein SP1132 X X X
hypothetical protein SP1133 X X X
hypothetical protein SP1134 X X X
hypothetical protein SP1135 X X X
conserved domain protein SP1136 X X X
GTP-binding protein, putative SP1137 X X X
hypothetical protein SP1138 X X X
hypothetical protein SP1139 X X X
hypothetical protein SP1140 X X X
hypothetical protein SP1141 X X X
hypothetical protein SP1142 X X X
conserved hypothetical protein SP1143 X X X
conserved hypothetical protein SP1144 X X X
hypothetical protein SP1145 X X X
hypothetical protein SP1146 X X X
integrase/recombinase, phage integrase family, truncation SP1147   X  
IS630-Spn1, transposase Orf2 SP1148      
IS630-Spn1, transposase Orf1 SP1149      
exonuclease RexB SP1151   X  
exonuclease RexA SP1152      
hypothetical protein SP1153      
immunoglobulin A1 protease SP1154 X X X
GTP-binding protein SP1155   X  
ribonuclease HII SP1156      
voltage-gated chloride channel family protein SP1157      
integrase/recombinase, phage integrase family SP1159      
lipoate-protein ligase, putative SP1160      
acetoin dehydrogenase complex, E3 component, dihydrolipoamide SP1161 X X X
acetoin dehydrogenase complex, E2 component, dihydrolipoamide SP1162 X X X
acetoin dehydrogenase, E1 component, beta subunit, putative SP1163      
acetoin dehydrogenase, E1 component, alpha subunit, putative SP1164      
MATE efflux family protein SP1166      
dihydroorotase, multifunctional complex type SP1167      
mutator MutT protein SP1168   X  
uracil-DNA glycosylase SP1169   X  
hypothetical protein SP1170   X  
hydrolase, haloacid dehalogenase-like family SP1171      
hypothetical protein SP1172 X X X
conserved hypothetical protein SP1173 X X X
conserved domain protein SP1174      
conserved domain protein SP1175      
phosphoenolpyruvate-protein phosphotransferase SP1176      
phosphocarrier protein HPr SP1177      
NrdH-redoxin SP1178 X X  
NrdH-redoxin SP1178   X X
ribonucleoside-diphosphate reductase 2, alpha subunit SP1179      
ribonucleoside-diphosphate reductase 2, beta subunit SP1180      
lactose phosphotransferase system repressor SP1182      
hypothetical protein SP1183 X X X
6-phospho-beta-galactosidase SP1184   X  
PTS system, lactose-specific IIBC components SP1185 X X X
PTS system, lactose-specific IIA component SP1186 X X X
transcription antiterminator LacT SP1187 X X X
hypothetical protein SP1189 X X X
tagatose 1,6-diphosphate aldolase SP1190 X X X
tagatose-6-phosphate kinase SP1191 X X X
galactose-6-phosphate isomerase, LacB subunit SP1192   X  
galactose-6-phosphate isomerase, LacA subunit SP1193   X  
lacX protein, truncation SP1194 X X X
IS1381, transposase OrfB SP1195      
IS1381, transposase OrfA, authentic frameshift SP1196   X  
conserved hypothetical protein SP1197 X X X
hypothetical protein SP1198 X X X
hypothetical protein SP1199 X X X
GTP-binding protein LepA SP1200      
serine/threonine protein phosphatase SP1201 X X X
DNA repair protein RecN SP1202      
transcriptional repressor, putative SP1203      
hemolysin A, putative SP1204   X  
geranyltranstransferase SP1205      
exodeoxyribonuclease VII, small subunit SP1206      
exodeoxyribonuclease VII, large subunit SP1207      
uridine kinase SP1208      
hypothetical protein SP1209 X X X
hypothetical protein SP1210   X  
tRNA pseudouridine synthase B SP1212      
conserved domain protein SP1213 X X X
transulfuration enzyme family protein, authentic point mutation SP1214 X X X
transporter, FNT family, putative SP1215 X X X
hypothetical protein SP1216 X X X
conserved hypothetical protein SP1218      
DNA gyrase subunit A SP1219      
L-lactate dehydrogenase SP1220      
type II restriction endonuclease, putative SP1221      
type II restriction endonuclease, putative SP1222      
conserved hypothetical protein SP1223   X  
conserved domain protein SP1224   X  
vicX protein SP1225      
sensory box sensor histidine kinase SP1226      
DNA-binding response regulator SP1227      
A/G-specific adenine glycosylase SP1228      
formate--tetrahydrofolate ligase SP1229      
conserved hypothetical protein SP1230      
flavoprotein SP1231      
membrane protein SP1232   X  
hypothetical protein SP1233   X  
transcriptional regulator, biotin repressor family SP1234 X X X
MutT/nudix family protein SP1235   X  
acetyltransferase, GNAT family SP1236 X X X
acetyltransferase, GNAT family SP1237 X X X
excinuclease ABC, subunit B SP1238      
conserved hypothetical protein SP1240      
amino acid ABC transporter, amino acid-binding protein/permeas SP1241      
amino acid ABC transporter, ATP-binding protein SP1242      
glucose-6-phosphate 1-dehydrogenase SP1243      
signal recognition particle-docking protein FtsY SP1244      
Cof family protein SP1245   X  
Cof family protein SP1246      
conserved hypothetical protein SP1247      
ribonuclease III SP1248   X  
conserved hypothetical protein SP1249      
conserved domain protein SP1250 X X X
endonuclease, putative SP1251 X X X
hypothetical protein SP1252 X X X
hypothetical protein SP1254 X X X
3-isopropylmalate dehydratase, small subunit, putative SP1255   X  
conserved hypothetical protein SP1256 X X X
3-isopropylmalate dehydrogenase, authentic point mutation SP1257   X  
2-isopropylmalate synthase, putative SP1258      
conserved hypothetical protein SP1259   X  
copper homeostasis protein CutC SP1260      
conserved hypothetical protein SP1261   X  
IS1167, transposase SP1262      
DNA topoisomerase I SP1263      
conserved domain protein SP1264   X  
DNA processing protein DprA, putative SP1266      
licC protein SP1267      
licB protein SP1268      
choline kinase SP1269      
alcohol dehydrogenase, zinc-containing SP1270      
cytidine diphosphocholine pyrophosphorylase, putative SP1271      
polysaccharide biosynthesis protein, putative SP1272      
licD1 protein SP1273      
licD2 protein SP1274   X  
carbamoyl-phosphate synthase, large subunit SP1275      
carbamoyl-phosphate synthase, small subunit SP1276      
aspartate carbamoyltransferase SP1277      
pyrimidine operon regulatory protein SP1278      
endonuclease III SP1279      
conserved hypothetical protein SP1280      
hypothetical protein SP1281 X X X
ABC transporter, ATP-binding protein SP1282   X  
heat shock protein HtpX SP1283      
lemA protein SP1284      
glucose-inhibited division protein B SP1285      
uracil permease SP1286      
signal recognition particle protein SP1287      
conserved hypothetical protein SP1288   X  
hypothetical protein SP1289   X  
conserved hypothetical protein SP1290      
Cof family protein SP1291   X  
SAP domain protein SP1292 X X X
ribosomal protein L19 SP1293      
crcB protein SP1294   X  
crcB protein SP1295      
chorismate mutase, putative SP1296      
flavodoxin SP1297      
DHH subfamily 1 protein SP1298      
ribosomal protein L31 SP1299      
hypothetical protein SP1300 X X X
transposase family protein, degenerate SP1301 X X X
conserved hypothetical protein SP1302   X  
NADP-specific glutamate dehydrogenase SP1306      
hypothetical protein SP1307   X  
toxin secretion ATP-binding protein, truncation SP1308      
IS1381, transposase OrfB, authentic frameshift SP1309   X  
IS1381, transposase OrfA SP1310      
IS66 family element, Orf3, degenerate SP1311      
transposase family protein, degenerate SP1312   X  
IS66 family element, Orf2, interruption SP1313   X  
IS66 family element, Orf1 SP1314 X X X
v-type sodium ATP synthase, subunit D SP1315 X X X
v-type sodium ATP synthase, subunit B SP1316 X X X
v-type sodium ATP synthase, subunit A SP1317 X X X
v-type sodium ATP synthase, subunit G SP1318 X X X
v-type sodium ATP synthase, subunit C SP1319 X X X
v-type sodium ATP synthase, subunit E SP1320 X X X
v-type sodium ATP synthase, subunit K SP1321 X X X
v-type sodium ATP synthase, subunit I SP1322 X X X
hypothetical protein SP1323 X X X
ROK family protein SP1324 X X X
oxidoreductase, Gfo/Idh/MocA family SP1325 X X X
neuraminidase, putative SP1326 X X X
conserved hypothetical protein SP1327 X X X
sodium:solute symporter family protein SP1328 X X X
N-acetylneuraminate lyase SP1329 X X X
N-acetylmannosamine-6-P epimerase, putative SP1330 X X X
phosphosugar-binding transcriptional regulator, putative SP1331 X X X
conserved domain protein SP1332 X X X
hypothetical protein SP1333   X  
conserved hypothetical protein SP1334 X X X
hypothetical protein SP1335 X X X
type II DNA modification methyltransferase spn5252IP SP1336 X X X
IS1380-Spn1, transposase SP1337 X X X
hypothetical protein SP1338 X X X
hypothetical protein SP1340   X  
ABC transporter, ATP-binding protein SP1341   X  
toxin secretion ABC transporter, ATP-binding/permease protein SP1342   X  
prolyl oligopeptidase family protein SP1343   X  
conserved hypothetical protein SP1344 X X X
hypothetical protein SP1345   X  
conserved hypothetical protein SP1346 X X X
hypothetical protein SP1347      
conserved hypothetical protein SP1348 X X X
hypothetical protein SP1349 X X X
conserved domain protein SP1350 X X X
hypothetical protein SP1351 X X X
IS1380-Spn1, transposase SP1352 X X X
ribosomal protein L7/L12 SP1354      
ribosomal protein L10 SP1355      
Atz/Trz family protein SP1356      
ABC transporter, ATP-binding/permease protein SP1357      
ABC transporter, ATP-binding/permease protein SP1358      
peptide methionine sulfoxide reductase SP1359      
homoserine kinase SP1360      
homoserine dehydrogenase SP1361      
putative transcriptional regulator MecA SP1362      
conserved domain protein SP1363      
hypothetical protein SP1364 X X X
glycosyl transferase, family 2 SP1365      
glycosyl transferase, group 1 SP1366      
licD3 protein SP1367      
psr protein SP1368      
prephenate dehydratase SP1369      
shikimate kinase SP1370      
3-phosphoshikimate 1-carboxyvinyltransferase SP1371      
conserved hypothetical protein SP1372      
prephenate dehydrogenase SP1373      
chorismate synthase SP1374      
3-dehydroquinate synthase SP1375      
shikimate 5-dehydrogenase SP1376      
3-dehydroquinate dehydratase SP1377      
conserved hypothetical protein SP1378      
hypothetical protein SP1379 X X X
hypothetical protein SP1380   X  
ABC transporter, ATP-binding protein SP1381 X X X
alpha-amylase SP1382 X X X
alanyl-tRNA synthetase SP1383      
conserved hypothetical protein SP1384      
hypothetical protein SP1385   X  
spermidine/putrescine ABC transporter, spermidine/putrescine-b SP1386      
SPermidine/putrescine ABC transporter, permease protein SP1387      
SPermidine/putrescine ABC transporter, permease protein SP1388      
SPermidine/putrescine ABC transporter, ATP-binding protein SP1389      
UDP-N-acetylenolpyruvoylglucosamine reductase SP1390      
conserved hypothetical protein SP1391   X  
alpha-acetolactate decarboxylase SP1392      
conserved hypothetical protein SP1393      
amino acid ABC transporter, amino acid-binding protein SP1394      
phosphate transport system regulatory protein PhoU, putative SP1395      
phosphate ABC transporter, ATP-binding protein, putative SP1396      
phosphate ABC transporter, ATP-binding protein, putative SP1397      
phosphate ABC transporter, permease protein, putative SP1398      
phosphate ABC transporter, permease protein, putative SP1399      
phosphate ABC transporter, phosphate-binding protein, putative SP1400 X   X
hypothetical protein SP1401      
NOL1/NOP2/sun family protein SP1402   X  
inositol monophosphatase family protein SP1403      
conserved hypothetical protein SP1404      
conserved hypothetical protein SP1405      
hypothetical protein SP1406      
hydrolase, haloacid dehalogenase-like family SP1407      
acyl-ACP thioesterase, putative SP1408      
oxygen-independent coproporphyrinogen III oxidase, putative SP1409      
conserved hypothetical protein SP1410      
conserved hypothetical protein SP1411      
prolipoprotein diacylglyceryl transferase SP1412      
Hpr(Ser) kinase/phosphatase SP1413      
ribosomal protein S21 SP1414      
ribosomal protein S21 SP1414 X X X
glucosamine-6-phosphate isomerase SP1415      
S-adenosylmethionine:tRNA ribosyltransferase-isomerase SP1416      
pspC protein, degenerate SP1417   X  
IS1380-Spn1, transposase SP1418 X X X
acetyltransferase, GNAT family SP1419      
NH(3)-dependent NAD(+) synthetase SP1420 X   X
conserved hypothetical protein SP1421      
hypothetical protein SP1422 X X X
transcriptional repressor, putative SP1423 X X X
hypothetical protein SP1424 X X X
ABC transporter, ATP-binding protein SP1426   X  
peptidase, U32 family SP1427      
conserved hypothetical protein SP1428   X  
peptidase, U32 family SP1429      
type II restriction endonuclease, putative, authentic point mu SP1430      
type II DNA modification methyltransferase, putative SP1431   X  
hypothetical protein SP1432 X X X
transcriptional regulator, araC family SP1433      
ABC transporter, ATP-binding/permease protein SP1434 X X X
ABC transporter, ATP-binding protein SP1435 X X X
hypothetical protein SP1436 X X X
conserved domain protein SP1437 X X X
ABC transporter, ATP-binding protein SP1438 X X X
IS1380-Spn1, transposase SP1439 X X X
ABC transporter, ATP-binding protein, fragment SP1440 X X X
IS66 family element, Orf3, degenerate SP1441   X  
IS66 family element, Orf2 SP1442   X  
IS66 family element, Orf1 SP1443 X X X
IS1167, transposase SP1444      
GMP synthase SP1445      
transcriptional regulator, GntR family SP1446 X X X
membrane protein SP1447   X  
conserved hypothetical protein SP1448      
cppA protein SP1449      
platelet activating factor, putative SP1450 X X X
Cof family protein SP1451   X  
hypothetical protein SP1452   X  
conserved domain protein SP1453   X  
hypothetical protein SP1454 X X X
hypothetical protein SP1455 X X X
polypeptide deformylase SP1456      
spoU rRNA methylase family protein SP1457      
thioredoxin reductase SP1458      
hypothetical protein SP1459 X X X
amino acid ABC transporter, ATP-binding protein SP1460      
amino acid ABC transporter, permease protein SP1461      
conserved hypothetical protein SP1462      
methylated-DNA--protein-cysteine S-methyltransferase SP1463      
acetyltransferase, GNAT family SP1464      
hypothetical protein SP1465      
hemolysin SP1466      
conserved hypothetical protein SP1467      
pyridoxine biosynthesis protein SP1468      
NADH oxidase SP1469      
thiamine biosynthesis protein ApbE, putative SP1470 X X X
oxidoreductase, putative SP1471   X  
oxidoreductase, putative SP1472 X X X
conserved hypothetical protein SP1473   X  
glycyl-tRNA synthetase, beta subunit SP1474      
glycyl-tRNA synthetase, alpha subunit SP1475      
hypothetical protein SP1476      
hypothetical protein SP1476 X X X
hypothetical protein SP1477      
oxidoreductase, aldo/keto reductase family SP1478      
peptidoglycan N-acetylglucosamine deacetylase A SP1479      
hypothetical protein SP1480 X   X
oxidoreductase, Gfo/Idh/MocA family SP1482      
ATP-dependent RNA helicase, DEAD/DEAH box family SP1483      
transposase family protein, authentic frameshift SP1484   X  
IS3-Spn1, transposase SP1485 X X X
IS3-Spn1, hypothetical protein, degenerate SP1486 X X X
hypothetical protein SP1487   X  
hypothetical protein SP1488   X  
translation elongation factor Tu SP1489      
glycerol uptake facilitator protein, putative SP1491      
cell wall surface anchor family protein SP1492 X X X
hypothetical protein SP1493 X X X
hypothetical protein SP1494      
hypothetical protein SP1495 X X X
transposase, IS630-Spn1 related, Orf2 SP1496 X X X
transposase, IS630-Spn1 related, Orf1, authentic frameshift SP1497 X X X
phosphoglucomutase SP1498      
bacterocin transport accessory protein SP1499      
amino acid ABC transporter, amino acid-binding protein SP1500      
amino acid ABC transporter, ATP-binding protein SP1501      
amino acid ABC transporter, permease protein SP1502      
IS1380-Spn1, transposase SP1503 X X X
TPR domain protein SP1504      
membrane protein SP1505      
conserved hypothetical protein SP1506      
ATP synthase F1, epsilon subunit SP1507      
ATP synthase F1, beta subunit SP1508      
ATP synthase F1, gamma subunit SP1509      
ATP synthase F1, alpha subunit SP1510      
ATP synthase F1, delta subunit SP1511      
ATP synthase F0, B subunit SP1512 X X  
ATP synthase F0, A subunit SP1513      
ATP synthase F0, C subunit SP1514      
IS1239, transposase, putative, degenerate SP1515 X X X
acetyltransferase, GNAT family SP1516      
transcription elongation factor GreA SP1517      
conserved hypothetical protein SP1518      
acetyltransferase, GNAT family SP1519   X  
acetyltransferase, GNAT family SP1520      
UDP-N-acetylmuramate--alanine ligase SP1521      
conserved domain protein SP1522      
Snf2 family protein SP1523      
aminotransferase, class II SP1524   X  
transulfuration enzyme family protein SP1525      
ABC transporter, ATP-binding protein authentic frameshift SP1526   X  
oligopeptide ABC transporter, oligopeptide-binding protein Ali SP1527      
polysaccharide biosynthesis protein, putative SP1529      
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate li SP1530      
hypothetical protein SP1531   X  
conserved domain protein, authentic frameshift SP1532   X  
conserved domain protein SP1533   X  
inorganic pyrophosphatase, manganese-dependent SP1534      
conserved hypothetical protein SP1535      
conserved hypothetical protein SP1536      
general stress protein 13, putative SP1537      
cof family protein/peptidyl-prolyl cis-trans isomerase, cyclop SP1538      
ribosomal protein S18 SP1539      
single-strand binding protein SP1540      
ribosomal protein S6 SP1541      
asparaginyl-tRNA synthetase SP1542      
conserved hypothetical protein, authentic point mutation SP1543      
aspartate aminotransferase SP1544      
conserved hypothetical protein SP1545      
conserved domain protein SP1546      
conserved hypothetical protein SP1547      
hypothetical protein SP1548      
polypeptide deformylase SP1549      
glutathione S-transferase family protein SP1550      
cation-transporting ATPase, E1-E2 family SP1551      
cation efflux family protein SP1552      
ABC transporter, ATP-binding protein SP1553      
polyA polymerase family protein SP1554 X X  
polyA polymerase family protein SP1554     X
dihydrodipicolinate reductase SP1555      
hypothetical protein SP1556 X X X
degV family protein SP1557      
hypothetical protein SP1558      
phosphoglucomutase/phosphomannomutase family protein SP1559      
conserved hypothetical protein SP1560      
conserved hypothetical protein SP1561      
hypothetical protein SP1562 X X X
pyridine nucleotide-disulphide oxidoreductase family protein SP1563      
conserved hypothetical protein SP1564      
conserved hypothetical protein SP1565      
conserved hypothetical protein SP1566      
endoribonuclease L-PSP SP1567      
GTP-binding protein SP1568      
ATP-dependent Clp protease, ATP-binding subunit ClpX SP1569      
hypothetical protein SP1570   X  
dihydrofolate reductase SP1571      
non-heme iron-containing ferritin SP1572      
lysozyme SP1573      
triosephosphate isomerase SP1574      
conserved hypothetical protein SP1575      
homoserine O-succinyltransferase SP1576      
adenine phosphoribosyltransferase SP1577      
methyltransferase, putative SP1578      
sugar ABC transporter, ATP-binding protein SP1580      
hypothetical protein SP1581 X X X
IS1167, transposase SP1582      
isochorismatase family protein SP1583      
transcriptional regulator, putative SP1584      
ATP-dependent RNA helicase, putative SP1586      
oxalate:formate antiporter SP1587      
oxidoreductase, pyridine nucleotide-disulfide, class I SP1588      
oxidoreductase, pyridine nucleotide-disulfide, class I SP1588 X X X
Mur ligase family protein SP1589      
conserved hypothetical protein SP1590      
proline dipeptidase SP1591      
conserved domain protein SP1592 X X X
IS3-Spn1, transposase, authentic point mutation SP1593 X X X
IS3-Spn1, hypothetical protein, interruption SP1594   X  
IS1380-Spn1, transposase SP1595 X X X
IS3-Spn1, hypothetical protein, interruption SP1596 X X X
conserved hypothetical protein SP1597   X  
phosphomethylpyrimidine kinase, putative SP1598   X  
tRNA pseudouridine synthase A SP1599   X  
hypothetical protein SP1600   X  
conserved hypothetical protein SP1601      
phnA protein SP1602      
cytidylate kinase SP1603      
hypothetical protein SP1604      
ferredoxin SP1605      
glycosyl transferase, family 2 SP1606 X   X
UDP-glucose 4-epimerase SP1607      
oxidoreductase, DadA family protein SP1608   X  
conserved hypothetical protein SP1609   X  
Bcl-2 family protein SP1610 X X X
conserved domain protein SP1612 X X X
IS3-Spn1, transposase, authentic point mutation SP1613   X  
IS3-Spn1, hypothetical protein, degenerate SP1614 X X X
transketolase, authentic frameshift SP1615   X  
ribulose-phosphate 3-epimerase family protein SP1616 X X X
PTS system, IIC component SP1617 X X X
PTS system, IIB component SP1618 X X X
PTS system, IIA component SP1619 X X X
PTS system, nitrogen regulatory component IIA, putative SP1620 X X X
transcription antiterminator BglG family protein, authentic fr SP1621 X X X
transposase, IS200 family SP1622 X X X
cation-transporting ATPase, E1-E2 family SP1623      
acyltransferase family protein SP1624   X  
acyltransferase family protein SP1624 X X X
cadmium resistance transporter, putative SP1625      
ribosomal protein S15 SP1626      
conserved hypothetical protein SP1627 X X X
hypothetical protein SP1628 X X X
hypothetical protein SP1630      
threonyl-tRNA synthetase SP1631      
sensor histidine kinase SP1632   X  
DNA-binding response regulator SP1633      
hypothetical protein SP1634   X  
hypothetical protein SP1635 X X X
Rrf2 family protein SP1636      
conserved hypothetical protein SP1637      
iron-dependent transcriptional regulator SP1638      
IS1167, transposase SP1639      
hypothetical protein SP1640   X  
conserved domain protein SP1641      
hypothetical protein SP1642   X  
hypothetical protein SP1643 X X X
conserved hypothetical protein SP1644      
GTP pyrophosphokinase SP1645      
metallo-beta-lactamase superfamily protein SP1646      
endopeptidase O SP1647 X   X
manganese ABC transporter, ATP-binding protein SP1648      
manganese ABC transporter, permease protein, putative, authent SP1649      
manganese ABC transporter, manganese-binding adhesion liprotei SP1650      
thiol peroxidase SP1651      
hypothetical protein SP1652   X  
ABC transporter, ATP-binding protein SP1653      
conserved hypothetical protein SP1654   X  
phosphoglycerate mutase SP1655      
hypothetical protein SP1656 X X X
hypothetical protein SP1657 X X X
hypothetical protein SP1658   X  
isoleucyl-tRNA synthetase SP1659      
hypothetical protein SP1660      
cell division protein DivIVA SP1661      
ylmH protein SP1662      
ylmG protein SP1663      
ylmF protein SP1664      
ylmE protein SP1665      
cell division protein FtsZ SP1666      
cell division protein FtsA SP1667      
hypothetical protein SP1668   X  
MutT/nudix family protein SP1669 X X X
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-a SP1670      
D-alanine--D-alanine ligase SP1671      
recombination protein RecR SP1672      
penicillin-binding protein 2B SP1673      
phosphosugar-binding transcriptional regulator, putative SP1674      
ROK family protein SP1675      
N-acetylneuraminate lyase, putative SP1676   X  
hypothetical protein SP1677 X X X
hypothetical protein SP1679 X X X
conserved hypothetical protein SP1680 X X X
sugar ABC transporter, permease protein SP1681   X  
sugar ABC transporter, permease protein SP1682   X  
sugar ABC transporter, sugar-binding protein SP1683   X  
PTS system, IIBC components SP1684   X  
conserved hypothetical protein SP1685      
oxidoreductase, Gfo/Idh/MocA family SP1686 X X X
neuraminidase B SP1687 X X X
ABC transporter, permease protein SP1688 X X X
ABC transporter, permease protein SP1689 X X X
ABC transporter, substrate-binding protein SP1690 X X X
conserved hypothetical protein SP1691 X X X
IS1167, transposase SP1692      
neuraminidase A, authentic frameshift SP1693   X  
acetyl xylan esterase, putative SP1695      
ATP-dependent DNA helicase RecG SP1697      
alanine racemase SP1698      
holo-(acyl-carrier protein) synthase SP1699      
phospho-2-dehydro-3-deoxyheptonate aldolase SP1700      
phospho-2-dehydro-3-deoxyheptonate aldolase SP1701      
preprotein translocase, SecA subunit SP1702      
conserved domain protein SP1703 X X X
ABC transporter, ATP-binding protein SP1704 X X X
hypothetical protein SP1705 X X X
hypothetical protein SP1706 X X X
hypothetical protein SP1707 X X X
hypothetical protein SP1708   X  
phosphoglycerate dehydrogenase-related protein SP1709      
nitroreductase family protein SP1710 X   X
primosomal protein DnaI SP1711      
hypothetical protein SP1712      
conserved hypothetical protein SP1713      
transcriptional regulator, GntR family SP1714      
ABC transporter, ATP-binding protein SP1715      
conserved hypothetical protein SP1716      
ABC transporter, ATP-binding protein SP1717      
IS1239, transposase, putative, degenerate SP1719 X X X
conserved hypothetical protein SP1720      
fructokinase SP1721   X  
PTS system IIABC components SP1722 X X X
hypothetical protein SP1723 X X X
sucrose-6-phosphate hydrolase SP1724   X  
sucrose operon repressor SP1725      
3-hydroxy-3-methylglutaryl-CoA reductase SP1726      
hydroxymethylglutaryl-CoA synthase SP1727      
hypothetical protein SP1728      
IS1381, transposase OrfA/OrfB, truncation SP1729      
hypothetical protein SP1730      
conserved hypothetical protein SP1731   X  
serine/threonine protein kinase SP1732      
phosphatase, putative SP1733      
rRNA methyltransferase RsmB SP1734   X  
methionyl-tRNA formyltransferase SP1735      
primosomal protein N SP1736 X X X
DNA-directed RNA polymerase, omega subunit, putative SP1737      
guanylate kinase SP1738      
KH domain protein SP1739      
conserved hypothetical protein SP1740 X X X
conserved hypothetical protein SP1741 X X X
conserved hypothetical protein SP1742   X  
conserved hypothetical protein SP1743      
iojap-related protein SP1744      
isochorismatase family protein SP1745      
conserved hypothetical protein SP1746      
conserved hypothetical protein SP1747      
conserved hypothetical protein SP1748      
GTP-binding protein SP1749      
conserved hypothetical protein SP1750      
magnesium transporter, CorA family, putative SP1751      
conserved domain protein SP1752      
sodium/dicarboxylate symporter family protein SP1753      
conserved hypothetical protein SP1754      
hypothetical protein SP1755 X X X
conserved domain protein SP1756 X X X
conserved hypothetical protein SP1757 X X X
glycosyl transferase, group 1 SP1758 X X X
preprotein translocase, SecA subunit SP1759 X X X
conserved domain protein SP1760 X X X
hypothetical protein SP1761 X X X
hypothetical protein SP1762 X X X
preprotein translocase SecY family protein SP1763 X X X
glycosyl transferase, family 2 SP1764 X X X
glycosyl transferase, family 8 SP1765 X X X
glycosyl transferase, family 8 SP1766 X X X
glycosyl transferase, family 8 SP1767 X X X
conserved hypothetical protein SP1768 X X X
glycosyl transferase, authentic frameshift SP1769 X X X
glycosyl transferase, family 8 SP1770 X X X
glycosyl transferase, family 2/glycosyl transferase family 8 SP1771 X X X
cell wall surface anchor family protein SP1772 X X X
IS630-Spn1, transposase Orf1/Orf2 degenerate SP1773 X X X
transcriptional regulator, putative SP1774      
conserved domain protein SP1775      
thioredoxin SP1776      
conserved hypothetical protein SP1777 X X X
aquaporin SP1778      
hypothetical protein SP1779      
oligoendopeptidase F, putative SP1780      
conserved hypothetical protein SP1781      
ribosomal protein L11 methyltransferase SP1782      
MutT/nudix family protein SP1783   X  
hypothetical protein SP1784 X X X
hypothetical protein SP1785      
conserved hypothetical protein SP1786 X X  
conserved hypothetical protein SP1786     X
hypothetical protein SP1787      
hypothetical protein SP1789 X X X
ATPase, AAA family SP1790   X  
integrase-related protein SP1791 X X X
IS1167, transposase SP1792      
hypothetical protein SP1793 X X X
hypothetical protein SP1794 X X X
sucrose-6-phosphate hydrolase, putative SP1795 X X X
ABC transporter, substrate-binding protein SP1796 X X X
ABC transporter, permease protein SP1797 X X X
ABC transporter, permease protein SP1798 X X X
sugar-binding transcriptional regulator, LacI family SP1799 X X X
transcriptional activator, putative SP1800 X X X
conserved hypothetical protein SP1801   X  
hypothetical protein SP1802      
conserved hypothetical protein SP1803   X  
general stress protein 24, putative SP1804      
hypothetical protein SP1805      
conserved domain protein SP1806 X X X
acetyltransferase, GNAT family SP1807 X X X
type IV prepilin peptidase, putative SP1808 X X X
transcriptional regulator SP1809      
hypothetical protein SP1810      
tryptophan synthase, alpha subunit SP1811      
tryptophan synthase, beta subunit SP1812      
N-(5-phosphoribosyl)-anthranilate isomerase SP1813   X  
indole-3-glycerol phosphate synthase SP1814      
anthranilate phosphoribosyltransferase SP1815      
anthranilate synthase component II SP1816      
anthranilate synthase component I SP1817      
sugar-binding transcriptional regulator, LacI family SP1821   X  
conserved domain protein SP1822 X X X
MgtC/SapB family protein SP1823   X  
ABC transporter, permease protein SP1824 X X X
ABC transporter, ATP-binding protein SP1825 X X X
ABC transporter, substrate-binding protein SP1826 X X X
hypothetical protein SP1827 X X X
UDP-glucose 4-epimerase SP1828 X X X
galactose-1-phosphate uridylyltransferase SP1829 X X X
phosphate transport system regulatory protein PhoU, putative SP1830 X X X
hypothetical protein SP1831 X X X
hypothetical protein SP1832 X X X
cell wall surface anchor family protein SP1833 X X X
hypothetical protein SP1834 X X X
hypothetical protein SP1835 X X X
hypothetical protein SP1836   X  
capsular polysaccharide biosynthesis protein, putative SP1837 X X  
capsular polysaccharide biosynthesis protein, putative SP1837     X
glycosyl transferase, putative SP1838      
ABC transporter, ATP-binding/permease protein SP1839      
ABC transporter, ATP-binding/permease protein SP1840 X X  
ABC transporter, ATP-binding/permease protein SP1840     X
conserved domain protein SP1841      
hypothetical protein SP1842   X  
hypothetical protein SP1844      
exodeoxyribonuclease SP1845      
conserved hypothetical protein, degenerate SP1846      
xanthine phosphoribosyltransferase SP1847   X  
xanthine permease SP1848   X  
DpnD protein SP1849      
type II restriction endonuclease DpnI SP1850   X  
conserved hypothetical protein SP1851 X X X
galactose-1-phosphate uridylyltransferase SP1852 X X X
galactokinase SP1853      
galactose operon repressor SP1854 X X X
alcohol dehydrogenase, zinc-containing SP1855      
transcriptional regulator, MerR family SP1856   X  
cation efflux system protein SP1857 X X X
transcriptional regulator, TetR family SP1858   X  
conserved domain protein SP1859   X  
choline transporter SP1860      
choline transporter SP1861      
hypothetical protein SP1862      
transcriptional regulator, MarR family SP1863      
conserved hypothetical protein SP1864      
glutamyl-aminopeptidase SP1865      
hypothetical protein SP1866 X X X
NAD-dependent epimerase/dehydratase family protein SP1867 X X X
iron-compound ABC transporter, permerase protein SP1869 X X X
iron-compound ABC transporter, permease protein SP1870 X X X
iron-compound ABC transporter, ATP-binding protein SP1871 X X X
iron-compound ABC transporter, iron-compound-binding protein SP1872 X X X
conserved hypothetical protein SP1873   X  
ribosomal large subunit pseudouridine synthase B SP1874      
conserved hypothetical protein SP1875      
conserved hypothetical protein SP1876      
integrase/recombinase, phage integrase family SP1877      
CBS domain protein SP1878      
conserved hypothetical protein SP1879      
HAM1 protein SP1880      
glutamate racemase SP1881      
conserved hypothetical protein SP1882   X  
dextran glucosidase DexS, putative SP1883   X  
PTS system, IIABC components SP1884 X X X
trehalose operon transcriptional repressor SP1885   X  
trehalose operon transcriptional repressor SP1885 X X X
IS1167, transposase, degenerate SP1886      
oligopeptide ABC transporter, ATP-binding protein AmiF SP1887      
oligopeptide ABC transporter, ATP-binding protein AmiE SP1888      
oligopeptide ABC transporter, permease protein AmiD SP1889      
oligopeptide ABC transporer, permease protein AmiC SP1890      
oligopeptide ABC transporter, oligopeptide-binding protein Ami SP1891      
hypothetical protein SP1892 X X X
hypothetical protein SP1893   X  
sucrose phosphorylase SP1894 X X X
sugar ABC transporter, permease protein SP1895 X X X
sugar ABC transporter, permease protein SP1896 X X X
sugar ABC transporter, sugar-binding protein SP1897   X  
alpha-galactosidase SP1898 X X X
msm operon regulatory protein SP1899 X X X
BirA bifunctional protein SP1900 X X X
RNA methyltransferase, TrmA family SP1901 X   X
conserved hypothetical protein SP1902 X X X
conserved hypothetical protein SP1903      
hypothetical protein SP1904 X X X
IS1167, transposase, interruption SP1905      
chaperonin, 60 kDa SP1906      
chaperonin, 10 kDa SP1907      
single-strand DNA-binding protein, authentic point mutation SP1908 X X X
oxidoreductase, short chain dehydrogenase/reductase family SP1909      
conserved hypothetical protein SP1910      
thioredoxin, putative SP1911      
hypothetical protein SP1912      
cspC-related protein, authentic point mutation SP1913 X   X
hypothetical protein SP1914 X   X
hypothetical protein SP1915 X   X
PAP2 family protein SP1916 X X X
hypothetical protein SP1917 X X X
ABC transporter, ATP-binding protein SP1918   X  
ABC transporter, permease protein SP1919 X X X
transcriptional regulator, MarR family SP1920 X X X
conserved hypothetical protein SP1922      
pneumolysin SP1923      
hypothetical protein SP1924      
hypothetical protein SP1925      
hypothetical protein SP1926      
IS1381, transposase OrfA SP1927   X  
IS1381, transposase OrfB SP1928      
hypothetical protein SP1930 X X X
hypothetical protein, fusion SP1931 X X X
hypothetical protein SP1933 X X X
hypothetical protein SP1934 X X X
hypothetical protein SP1935 X X X
type II restriction-modification system regulatory protein, pu SP1936 X X X
autolysin SP1937      
MATE efflux family protein DinF SP1939      
recA protein SP1940      
competence/damage-inducible protein CinA SP1941      
transcriptional regulator, putative SP1942      
acetyltransferase, GNAT family SP1943      
conserved hypothetical protein TIGR00150 SP1944      
hypothetical protein SP1945      
transcriptional regulator PlcR, putative SP1946   X  
hypothetical protein SP1947 X X X
conserved domain protein SP1948 X X X
hypothetical protein SP1949 X X X
bacteriocin formation protein, putative SP1950 X X X
conserved hypothetical protein SP1951 X X X
hypothetical protein SP1952 X X X
toxin secretion ABC transporter, ATP-binding/permease protein SP1953 X X X
serine protease, subtilase family, authentic frameshift SP1954   X  
hypothetical protein SP1955 X X X
hypothetical protein SP1956 X X X
ABC transporter, ATP-binding protein SP1957   X  
hypothetical protein SP1958 X X X
nucleoside diphosphate kinase SP1959      
DNA-directed RNA polymerase, beta subunit SP1960      
DNA-directed RNA polymerase, beta subunit SP1961      
CBS domain protein SP1963      
DNA-entry nuclease SP1964      
hypothetical protein SP1965 X X X
UDP-N-acetylglucosamine 1-carboxyvinyltransferase SP1966      
conserved hypothetical protein SP1967      
phosphopantetheine adenylyltransferase SP1968      
type II DNA modification methyltransferase, putative SP1969   X  
aspartate--ammonia ligase SP1970      
hypothetical protein SP1971 X X X
membrane protein SP1972      
spoU rRNA Methylase family protein SP1973 X   X
acylphosphatase SP1974 X X X
spoIIIJ family protein SP1975      
pyruvate formate-lyase-activating enzyme SP1976      
diaminopimelate decarboxylase SP1978      
pur operon repressor SP1979      
cmp-binding-factor 1 SP1980      
competence-induced protein Ccs50 SP1981      
conserved hypothetical protein SP1982      
ribulose-phosphate 3-epimerase SP1983      
conserved hypothetical protein TIGR00157 SP1984      
dimethyladenosine transferase SP1985 X X X
hypothetical protein SP1986   X  
ABC transporter, ATP-binding protein SP1987   X  
immunity protein, putative SP1988   X  
transcriptional regulator PlcR, putative SP1989   X  
primase-related protein SP1990      
hydrolase, putative SP1991      
cell wall surface anchor family protein SP1992      
aminotransferase, class I SP1994      
conserved hypothetical protein SP1995 X X X
universal stress protein family SP1996      
Cof family protein SP1997      
L-asparaginase, putative SP1998      
catabolite control protein A SP1999      
DNA-binding response regulator SP2000 X X X
sensor histidine kinase, putative SP2001   X  
conserved hypothetical protein SP2002 X X X
ABC transporter, ATP-binding protein SP2003   X  
hypothetical protein SP2004 X X X
hypothetical protein SP2005 X X X
transcriptional regulator ComX1 SP2006 X   X
transcription antitermination protein NusG SP2007      
preprotein translocase, SecE subunit, putative SP2008   X  
ribosomal protein L33 SP2009   X  
penicillin-binding protein 2A SP2010      
ribosomal large subunit pseudouridine synthase, RluD subfamily SP2011   X X
glyceraldehyde 3-phosphate dehydrogenase SP2012      
conserved hypothetical protein SP2013      
IS630-Spn1, transposase Orf2 SP2014   X  
IS630-Spn1, transposase Orf1 SP2015      
nicotinate-nucleotide pyrophosphorylase SP2016      
membrane protein SP2017 X    
transposase, IS3 family, degenerate SP2018 X   X
ABC transporter, ATP-binding protein, truncation SP2019   X X
transcriptional regulator, GntR family SP2020      
glycosyl hydrolase, family 1 SP2021      
PTS system, IIC component SP2022   X  
PTS system, IIB component SP2023      
PTS system, IIA component SP2024   X  
alcohol dehydrogenase, iron-containing SP2026   X  
conserved hypothetical protein SP2027      
phosphotyrosine protein phosphatase SP2028      
preprotein translocase, YajC subunit SP2029      
transketolase SP2030      
conserved hypothetical protein SP2031 X    
transcriptional regulator, BglG family SP2032 X X X
L-ribulose 5-phosphate 4-epimerase AraD, putative SP2033 X X X
hexulose-6-phosphate isomerase, putative SP2034   X X
hexulose-6-phosphate synthase, putative SP2035 X X  
PTS system, IIA component SP2036 X X X
PTS system, IIB component SP2037 X X X
PTS system, membrane component, putative SP2038 X X X
conserved hypothetical protein SP2039   X X
jag protein, putative SP2040   X  
spoIIIJ family protein SP2041      
ribonuclease P protein component SP2042      
acetate kinase SP2044      
conserved hypothetical protein SP2045      
conserved domain protein, authentic frameshift SP2046 X    
conserved domain protein SP2047 X X X
conserved hypothetical protein SP2048 X X X
conserved hypothetical protein SP2049 X X X
competence protein CglD SP2050 X   X
competence protein CglC SP2051   X X
competence protein CglB SP2052 X X  
competence protein CglA SP2053   X X
conserved hypothetical protein SP2054   X  
alcohol dehydrogenase, zinc-containing SP2055      
N-acetylglucosamine-6-phosphate deacetylase SP2056      
conserved hypothetical protein SP2057      
queuine tRNA-ribosyltransferase SP2058      
conserved hypothetical protein SP2059      
pyrrolidone-carboxylate peptidase SP2060      
conserved hypothetical protein SP2061 X X  
transcriptional regulator, MarR family SP2062   X X
LysM domain protein, authentic frameshift SP2063   X  
hydrolase, haloacid dehalogenase-like family SP2064      
MATE efflux family protein SP2065   X  
threonine synthase SP2066      
hypothetical protein SP2067      
cytidine/deoxycytidylate deaminase family protein SP2068      
glutamyl-tRNA synthetase SP2069      
glucose-6-phosphate isomerase SP2070      
conserved domain protein SP2071      
glutamine amidotransferase, class-I SP2072 X X  
ABC transporter, ATP-binding/permease protein SP2073   X X
transposase, IS116/IS110/IS902 family, degenerate SP2074      
ABC transporter, ATP-binding/permease protein SP2075      
DNA mismatch repair protein HexA, authentic frameshift SP2076      
transcriptional repressor, putative SP2077      
arginyl-tRNA synthetase SP2078   X  
IS1381, transposase OrfB SP2079      
IS1381, transposase OrfA, truncation SP2080      
conserved hypothetical protein SP2081   X  
response regulator SP2082      
sensor histidine kinase PnpS SP2083      
phosphate ABC transporter, phosphate-binding protein SP2084 X    
phosphate ABC transporter, permease protein SP2085 X X X
phosphate ABC transporter, permease protein SP2086 X X X
phosphate ABC transporter, ATP-binding protein SP2087 X X X
phosphate transport system regulatory protein PhoU SP2088 X X X
transposase, IS1380-Spn1 related, truncation SP2089 X X X
transcriptional regulator SP2090 X X X
glycerol-3-phosphate dehydrogenase (NAD(P)+) SP2091   X X
UTP-glucose-1-phosphate uridylyltransferase SP2092      
hypothetical protein SP2093 X    
conserved hypothetical protein SP2094   X X
5-formyltetrahydrofolate cyclo-ligase family protein SP2095      
peptidase, M20/M25/M40 family SP2096      
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase SP2097      
membrane protein SP2098      
penicillin-binding protein 1B SP2099      
tyrosyl-tRNA synthetase SP2100      
cation-transporting ATPase, EI-E2 family SP2101      
hypothetical protein SP2102      
rRNA (guanine-N1-)-methyltransferase SP2103   X  
hypothetical protein SP2104 X    
hypothetical protein SP2105 X X X
glycogen phosphorylase family protein SP2106   X X
4-alpha-glucanotransferase SP2107 X    
maltose/maltodextrin ABC transporter, maltose/maltodextrin-bin SP2108     X
maltodextrin ABC transporter, permease protein SP2109      
maltodextrin ABC transporter, permease protein SP2110 X    
malA protein SP2111   X X
maltose operon transcriptional repressor SP2112      
conserved hypothetical protein SP2113      
aspartyl-tRNA synthetase SP2114   X  
hypothetical protein SP2115      
conserved domain protein SP2116 X X  
hypothetical protein SP2117   X X
hypothetical protein SP2118 X X  
transcriptional regulator, putative SP2119 X X X
hypothetical protein SP2120 X X X
histidyl-tRNA synthetase SP2121   X X
conserved hypothetical protein SP2122      
conserved hypothetical protein SP2122 X X X
transcriptional regulator, authentic frameshift SP2123 X X  
conserved hypothetical protein SP2125   X X
dihydroxy-acid dehydratase SP2126   X  
transketolase, C-terminal subunit SP2127      
transketolase, N-terminal subunit SP2128   X  
PTS system, IIC component, putative SP2129   X  
PTS system, IIB component, putative SP2130 X X  
transcriptional regulator, BglG family SP2131 X X X
conserved hypothetical protein SP2132   X X
conserved domain protein SP2133      
ribosomal protein L32 SP2134   X  
ribosomal protein L33 SP2135   X  
choline binding protein PcpA SP2136 X    
IS1381, transposase OrfA, internal deletion SP2137   X X
IS1381, transposase OrfB SP2138   X  
hypothetical protein SP2139 X    
hypothetical protein SP2140 X X X
glycosyl hydrolase-related protein SP2141 X X X
ROK family protein SP2142   X X
conserved hypothetical protein SP2143 X X  
conserved hypothetical protein SP2144 X X X
antigen, cell wall surface anchor family SP2145 X X X
conserved hypothetical protein SP2146 X X X
hypothetical protein SP2147 X X X
arginine deiminase SP2148   X X
ornithine carbamoyltransferase SP2150      
carbamate kinase SP2151      
conserved hypothetical protein SP2152      
peptidase, M20/M25/M40 family SP2153 X    
IS3-Spn1, hypothetical protein, truncation SP2154 X X X
immunoglobulin A1 protease, degenerate SP2155   X X
SPFH domain/Band 7 family SP2156   X  
alcohol dehydrogenase, iron-containing SP2157 X    
L-fucose isomerase SP2158 X X X
fucolectin-related protein SP2159 X X X
conserved hypothetical protein SP2160 X X X
PTS system, IID component SP2161 X X X
PTS system, IIC component SP2162 X X X
PTS system, IIB component SP2163 X X X
PTS system, IIA component SP2164 X X X
fucose operon FucU protein SP2165 X X X
L-fuculose phosphate aldolase SP2166 X X X
L-fuculose kinase fucK, putative SP2167 X X X
fucose operon repressor, putative SP2168 X X X
zinc ABC transporter, zinc-binding adhesion liprotein SP2169   X X
zinc ABC transporter, permease protein SP2170      
zinc ABC transporter, ATP-binding protein SP2171      
adc operon repressor AdcR SP2172      
dltD protein SP2173      
D-alanyl carrier protein SP2174 X    
dltB protein SP2175   X X
D-alanine-activating enzyme SP2176      
hypothetical protein SP2177      
conserved hypothetical protein, interruption SP2178 X X  
IS1380-Spn1, transposase SP2179 X X X
conserved hypothetical protein, interruption SP2180 X X X
group II intron, maturase, degenerate SP2181 X X X
hypothetical protein SP2182   X X
hypothetical protein SP2183 X X  
glycerol uptake facilitator protein SP2184 X X X
hypothetical protein SP2185 X X X
glycerol kinase SP2186 X X X
conserved domain protein SP2187   X X
chaperonin, 33 kDa SP2188      
TIM-barrel protein, putative, NifR3 family SP2189      
choline binding protein A SP2190      
conserved hypothetical protein SP2191      
sensor histidine kinase SP2192      
DNA-binding response regulator SP2193      
ATP-dependent Clp protease, ATP-binding subunit SP2194   X  
transcriptional regulator CtsR SP2195      
ABC transporter, ATP-binding protein SP2196      
ABC transporter, substrate-binding protein, putative SP2197      
ABC transporter, permease protein SP2198      
conserved hypothetical protein SP2199      
hypothetical protein SP2200 X X  
choline binding protein D SP2201 X    
choline binding protein D SP2201   X X
conserved hypothetical protein SP2202   X X
replicative DNA helicase SP2203      
ribosomal protein L9 SP2204      
DHH subfamily 1 protein SP2205      
ribosomal subunit interface protein SP2206      
competence protein ComF, putative SP2207 X    
helicase, putative SP2208 X X X
conserved hypothetical protein SP2209   X X
cysteine synthase SP2210      
IS66 family element, Orf3, degenerate SP2211   X  
transposase family protein, truncation SP2212 X X  
IS66 family element, Orf2, interruption SP2213   X X
translation elongation factor Ts SP2214   X  
ribosomal protein S2 SP2215      
secreted 45 kd protein SP2216      
rod shpae-determining protein MreD, putative SP2217      
rod shape-determining protein MreC SP2218   X  
rod shape-determining protein MreC SP2218      
conserved hypothetical protein SP2219   X  
ABC transporter, ATP-binding protein SP2220      
ABC transporter, ATP-binding protein SP2221      
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransfe SP2222      
conserved hypothetical protein SP2223      
peptidase, M16 family SP2224      
conserved hypothetical protein SP2225      
conserved hypothetical protein SP2226      
recF protein SP2227   X  
inosine-5-monophosphate dehydrogenase SP2228   X  
tryptophanyl-tRNA synthetase SP2229      
ABC transporter, ATP-binding protein SP2230      
ABC transporter, permease protein, putative SP2231 X    
conserved hypothetical protein, authentic frameshift SP2232 X X X
hypothetical protein SP2233 X X X
transcriptional regulator, TetR family SP2234 X X X
response regulator ComE SP2235    X
putative sensor histidine kinase ComD SP2236      
competence stimulating peptide 2 SP2237   X  
conserved hypothetical protein SP2238      
serine protease SP2239   X  
spPspoJ protein SP2240