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Supplementary Information

Gene Expression Profiling of Pediatric Acute Myelogenous Leukemia

Section I: Patient Datasets

Table S2. Pediatric AML cytogenetics summary

Case identifier Subtypea MLL statusb Cytogenetic summary
inv16-#01 CBFβ-MYH11   inv(16)
inv16-#02 CBFβ-MYH11   inv(16)
inv16-#03 CBFβ-MYH11   inv(16) + misc non-recurrent
inv16-#04 CBFβ-MYH11   inv(16) + misc non-recurrent
inv16-#05 CBFβ-MYH11   inv(16) + misc non-recurrent
inv16-#06 CBFβ-MYH11   inv(16) + misc non-recurrent
inv16-#07 CBFβ-MYH11   inv(16) + misc non-recurrent
inv16-#08 CBFβ-MYH11   inv(16)
inv16-#09 CBFβ-MYH11   inv(16) + misc non-recurrent
inv16-#10 CBFβ-MYH11   inv(16) + misc non-recurrent
inv16-#11 CBFβ-MYH11   inv(16) + misc non-recurrent
inv16-#12 CBFβ-MYH11   inv(16)
inv16-#13 CBFβ-MYH11   inv(16)
inv16-#14 CBFβ-MYH11   inv(16)
MLL-#01 MLL t(11;19) t(11;19)(q23;p13.1)
MLL-#02 MLL t(9;11) t(9;11)(p22;q23)
MLL-#03 MLL t(6;11) t(6;11)(q27;q23)
MLL-#04 MLL t(3;11) t(3;11;10)(q28;q23;p11.2)
MLL-#05 MLL t(1;11) t(1;11)(q21;q23)
MLL-#06 MLL t(10;11) t(10;11)(p11.2;q23), + misc non-recurrent
MLL-#07 MLL t(9;11) t(9;11)(p21;q23) + misc non-recurrent
MLL-#08 MLL t(9;11) t(9;11)(p22;q23) + misc non-recurrent
MLL-#09 MLL t(7;9;11) t(7;9;11)(p15;p22;q23)
MLL-#10 MLL t(9;11) t(9;11)(p22;q23)
MLL-#11 MLL t(11;19) t(11;19)(q23;p13.1)
MLL-#12 MLL t(9;11) t(9;11)(p22;q23) + misc non-recurrent
MLL-#13 MLL t(1;11) t(1;11)(q21;q23)
MLL-#14 MLL t(11;19) t(11;19)(q23;p13.1)
MLL-#15 MLL t(1;11) t(1;11)(q21;q23)
MLL-#16 MLL t(10;11) t(10;11)(p12;q23)
MLL-#17 MLL t(9;11) t(9;11)(p22;q23)
MLL-#18 MLL t(9;11) t(9;11)(p22;q23)
MLL-#19 MLL t(10;11) t(10;11)(p13;q23) + misc non-recurrent
MLL-#20 MLL t(11;16) t(11;16)(q23;q24)
MLL-#21 MLL t(9;11) t(9;11)(p22;q23)
MLL-#22 MLL t(4;11) t(4;11)(q21;q23)
MLL-#23 MLL t(10;11) t(10;11)(p13;q23) + misc non-recurrent
t(15;17)-#01 PML-RARα   t(15;17)
t(15;17)-#02 PML-RARα   t(15;17),  +8
t(15;17)-#03 PML-RARα   t(15;17)
t(15;17)-#04 PML-RARα   t(15;17)
t(15;17)-#05 PML-RARα   t(15;17)
t(15;17)-#06 PML-RARα   t(15;17)
t(15;17)-#07 PML-RARα   ND
t(15;17)-#08 PML-RARα   ND
t(15;17)-#09 PML-RARα   ND
t(15;17)-#10 PML-RARα   t(15;17)
t(15;17)-#11 PML-RARα   t(15;17)
t(15;17)-#12 PML-RARα   t(15;17)
t(15;17)-#13 PML-RARα   t(15;17)
t(15;17)-#14 PML-RARα   t(15;17)
t(15;17)-#15 PML-RARα   t(15;17)
t(8;21)-#01 AML1-ETO   t(8;21)
t(8;21)-#02 AML1-ETO   t(8;21)
t(8;21)-#03 AML1-ETO   t(8;21) complex
t(8;21)-#04 AML1-ETO   t(8;21)
t(8;21)-#05 AML1-ETO   t(8;21)
t(8;21)-#06 AML1-ETO   t(8;21)
t(8;21)-#07 AML1-ETO   t(8;21)
t(8;21)-#08 AML1-ETO   t(8;21)
t(8;21)-#09 AML1-ETO   t(8;21) + misc non-recurrent
t(8;21)-#10 AML1-ETO   t(8;21) + misc non-recurrent
t(8;21)-#11 AML1-ETO   t(8;21)
t(8;21)-#12 AML1-ETO   t(8;21)
t(8;21)-#13 AML1-ETO   ND
t(8;21)-#14 AML1-ETO   ND
t(8;21)-#15 AML1-ETO   ND
t(8;21)-#16 AML1-ETO   ND
t(8;21)-#17 AML1-ETO   ND
t(8;21)-#18 AML1-ETO   t(8;21)
t(8;21)-#19 AML1-ETO   t(8;21) complex
t(8;21)-#20 AML1-ETO   t(8;21) complex
t(8;21)-#21 AML1-ETO   t(8;21)
Other-#01 Other   normal
Other-#02 Other   normal
Other-#03 Other MLL-PTD 13q-
Other-#04 Other   normal
Other-#05 Other   misc non-recurrent
Other-#06 Other   normal
Other-#07 Other MLL-PTD +11
Other-#08 Other MLL-PTD +8
Other-#09 Other MLL-PTD normal
Other-#10 Other   misc non-recurrent
Other-#11 Other   5q- misc non-recurrent
Other-#12 Other   +4
Other-#13 Other MLL-PTD normal
Other-#14 Other   normal
Other-#15 Other MLL-PTD normal
Other-#16 Other MLL-PTD misc non-recurrent
Other-#17 Other   normal
Other-#18 Other   t(16;21)(p11.2;q22)
Other-#19 Other   +4
Other-#20 Other MLL-PTD t(3;5)(q25.1;q34)
Other-#21 Other   t(6;9)(p23;q34)
Other-#22 Other MLL-PTD normal
Other-#23 Other   t(16;21)(?p11.2;q22)
Other-#24 Other   -7
Other-#25 Other   normal
Other-#26 Other MLL-PTD +8, misc
Other-#27 Other   misc non-recurrent
Other-#28 Other   7q-
Other-#29 Other   +8
Other-#30 Other   t(6;9)(p23;q34)
Other-#31 Other   misc non-recurrent
Other-#32 Other   normal
Other-#33 Other MLL-PTD +8
Other-#34 Other   -7
Other-#35 Other   misc non-recurrent
Other-#36 Other   misc non-recurrent
Other-#37 Other   normal
Other-#38 Other   misc non-recurrent
Other-#39 Other   normal
Other-#40 Other   +8
Other-#41 Other   9q-
Other-#42 Other MLL-PTD misc non-recurrent
Other-#43 Other MLL-PTD normal
Other-#44 Other   5q-, misc non-recurrent
Other-#45 Other   normal
Other-#46 Other   misc non-recurrent
Other-#47 Other   misc non-recurrent
Other-M7-#01 FAB-M7   misc non-recurrent
Other-M7-#02 FAB-M7   misc non-recurrent  (Down syndrome)
Other-M7-#03 FAB-M7   +8, misc non-recurrent
Other-M7-#04 FAB-M7   +21, misc non-recurrent
Other-M7-#05 FAB-M7   7q-, +21, misc non-recurrent
Other-M7-#06 FAB-M7   misc non-recurrent
Other-M7-#07 FAB-M7   misc non-recurrent (Down syndrome)
Other-M7-#08 FAB-M7   +8, misc non-recurrent
Other-M7-#09 FAB-M7   misc non-recurrent
Other-M7-#10 FAB-M7   misc non-recurrent

ND= not done.