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Evans, William, PharmD

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Veerman, Anjo J. P.

St. Jude Research >> ALL5 >> SupplementalTable3

Supplementary Information

Identification of genes associated with chemotherapy cross-resistance and treatment response in childhood acute lymphoblastic leukemia.

Supplemental Table3 : Cross-validation using gene expression scores for cross-resistance and VCR-ASP discordant resistance.

Spearman's rank correlation (rho) and P-value for top probe sets discriminating cross-resistance and vincristine-asparaginase (VCR-ASP) discordant resistance are listed. In each iteration, based on 10-fold cross-validation, genes were reselected ( A ) or were not reselected ( B ).

	A				B
	Cross-resistance		VCR-ASP discordance		Cross-resistance		VCR-ASP discordance
Probe sets	rho	P-value	rho	P-value	rho	P-value	rho	P-value
30	0.50	<0.0001	0.45	<0.0001	0.74	<0.0001	0.63	<0.0001
51	0.52	<0.0001	0.45	<0.0001	0.73	<0.0001	0.63	<0.0001
100	0.53	<0.0001	0.46	<0.0001	0.72	<0.0001	0.62	<0.0001
200	0.50	<0.0001	0.53	<0.0001	0.70	<0.0001	0.64	<0.0001

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