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Supplementary Information

Classification of Pediatric Acute Lymphoblastic Leukemia by Gene Expression Profile

The following tables contain a listing of the top 100 probe sets for each diagnostic subtypes ranked by their chi-square value
(Tables S3-S8). Each table contains the Affymetrix U133 series probe set number, a gene description, gene symbol, chromosomal location, and primary GenBank reference. Chi-square values were calculated utilizing only the samples in the training set in a differential diagnosis decision tree format as discussed in the text and illustrated in Figure 2 (Tables S3-S8) or by a parallel approach (Tables S9-S14). The calculation of the fold change was done in a parallel format using the total data set and comparing the mean signal value in the class versus the mean signal value in the non-class. The last column indicates whether this gene had previously been identified as a class discriminator using the U95Av2 data (old) or identified as a class discriminator only using the U133 data (new) (Tables S3-S8).

Table S3. Top 100 chi-square probe sets selected for BCR-ABL in decision tree format

  U133 probe set Gene description Symbol Location GenBank Reference Chi-square value E2A PBX1 above/below mean Fold change old or new
1 201579_at FAT tumor suppressor homolog 1 (Drosophila) FAT 4q34-q35 NM_005245.1 88.0 Above 9.9 old
2 201695_s_at nucleoside phosphorylase NP 14q13.1 NM_000270.1 88.0 Above 3.8 old
3 204674_at lymphoid-restricted membrane protein LRMP 12p12.3 NM_006152.1 88.0 Above 5.8 old
4 205253_at pre-B-cell leukemia transcription factor 1 PBX1 1q23 NM_002585.1 88.0 Above 3549.2 old
5 212148_at pre-B-cell leukemia transcription factor 1, splice variant PBX1 1q23 BF967998 88.0 Above 5283.5 old
6 212151_at pre-B-cell leukemia transcription factor 1, splice variant PBX1 1q23 BF967998 88.0 Above 7472.2 old
7 212371_at DKFZp586C1019 DKFZp586C1019 1 AL049397.1 88.0 Above 2.5 old
8 219155_at retinal degeneration B beta RDGBB 17q24.2 NM_012417.1 88.0 Above 2.7 new
9 225483_at hypothetical protein MGC10485 MGC10485 11q25 AI971602 88.0 Above 7.7 new
10 227439_at E2a-Pbx1-associated protein EB-1 12 AW005572 88.0 Above 269.8 new
11 227949_at Q9H4T4 like H17739 20q13.32 AL357503 88.0 Above 59.3 new
12 230306_at hypothetical protein MGC10485 MGC10485 11q25 AA514326 88.0 Above 19.2 new
13 231095_at retinal degeneration B beta RDGBB 17q24.2 AW193811 88.0 Above 25.6 new
14 203372_s_at STAT induced STAT inhibitor-2 SOCS2 12q AB004903.1 80.6 Below 23.4 old
15 206028_s_at c-mer proto-oncogene tyrosine kinase MERTK 2q14.1 NM_006343.1 80.6 Above 23.7 old
16 206181_at signaling lymphocytic activation molecule SLAM 1q22-q23 NM_003037.1 80.6 Above 6.3 old
17 208788_at homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2 HELO1 6p21.1-p12.1 AL136939.1 80.6 Above 2.2 old
18 209760_at KIAA0922 protein KIAA0922 4q31.23 AL136932.1 80.6 Above 2.9 old
19 35974_at lymphoid-restricted membrane protein LRMP 12p12.3 U10485 80.6 Above 6.2 old
20 38340_at huntingtin interacting protein 12 HIP12 12q24 AB014555 80.6 Above 3.8 old
21 208644_at ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) ADPRT 1q41-q42 M32721.1 80.2 Above 3.0 old
22 212789_at KIAA0056 protein KIAA0056 11q25 AI796581 80.2 Above 3.9 old
23 221113_s_at wingless-type MMTV integration site family, member 16 WNT16 7q31 NM_016087.1 80.2 Above 2547.6 new
24 224022_x_at wingless-type MMTV integration site family, member 16 WNT16 7q31 AF169963.1 80.2 Above 569.1 new
25 231040_at EST   9 AW512988 80.2 Above 16.4 new
26 232289_at FLJ14167 FLJ14167 17 BF237871 80.2 Above 144.1 new
27 235666_at EST FLJ20489 10 AA903473 80.2 Above 654.6 new
28 203373_at STAT induced STAT inhibitor-2 SOCS2 12q NM_003877.1 74.2 Below 24.8 old
29 210785_s_at basement membrane-induced gene ICB-1 1p35.3 AB035482.1 74.2 Below 4.1 old
30 224733_at chemokine-like factor super family 3 CKLFSF3 16q23.1 AL574900 74.2 Below 41.7 new
31 225235_at hypothetical protein MGC14859 MGC14859 5q35.3 AW007710 74.2 Above 3.6 new
32 204114_at nidogen 2 (osteonidogen) NID2 14q21-q22 NM_007361.1 73.1 Above 15.1 old
33 211913_s_at c-mer proto-oncogene tyrosine kinase MERTK 2q14.1 L08961.1 72.8 Above 37.7 old
34 219551_at uncharacterized bone marrow protein BM040 BM040 3q21.1 NM_018456.1 72.8 Above 3.0 New
35 223693_s_at hypothetical protein FLJ10324 FLJ10324 7p22 AL136731.1 72.8 Above 65.6 New
36 200600_at moesin MSN Xq11.2-q12 NM_002444.1 72.5 Below 2.2 Old
37 213909_at FLJ12280 FLJ12280 3 AU147799 72.5 Above 12.5 New
38 221669_s_at acyl-Coenzyme A dehydrogenase family, member 8 ACAD8 11q25 BC001964.1 72.5 Above 2.6 New
39 235911_at ESTs, Weakly similar to PIHUB6 salivary proline-rich protein precursor PRB1 (large allele)   3 AI885815 72.5 Above 36.6 New
40 243533_x_at ESTs     H09663 72.5 Above 23.2 New
41 202615_at DKFZp686D0521 DKFZp686D0521 9 BF222895 68.6 Below 6.2 Old
42 204774_at ecotropic viral integration site 2A EVI2A 17q11.2 NM_014210.1 68.6 Below 3.0 New
43 218283_at synovial sarcoma translocation gene on chromosome 18-like 2 SS18L2 3p21 NM_016305.1 68.6 Above 1.6 New
44 209130_at synaptosomal-associated protein, 23kDa SNAP23 15q14 BC003686.1 67.8 Below 1.9 New
45 228580_at serine protease HTRA3 HTRA3 4p16.1 AI828007 66.6 Above 3.8 New
46 202796_at synaptopodin KIAA1029 5q33.1 NM_007286.1 66.5 Above 52.3 Old
47 218640_s_at phafin 2 FLJ13187 8q21.3 NM_024613.1 66.5 Above 3.1 New
48 235099_at ESTs, Weakly similar to PLLP_HUMAN Plasmolipin [H.sapiens]   3 AW080832 66.5 Above 6.7 New
49 201889_at family with sequence similarity 3, member C FAM3C 7q22.1-q31.1 NM_014888.1 65.3 Above 4.6 New
50 202106_at golgi autoantigen, golgin subfamily a, 3 GOLGA3 12q24.33 NM_005895.1 65.3 Above 3.3 Old
51 202208_s_at ADP-ribosylation factor-like 7 ARL7 2q37.2 BC001051.1 65.3 Above 3.2 Old
52 205173_x_at CD58 antigen, (lymphocyte function-associated antigen 3) CD58 1p13 NM_001779.1 65.3 Above 2.4 Old
53 211744_s_at CD58 antigen, (lymphocyte function-associated antigen 3) CD58 1p13 BC005930.1 65.3 Above 2.5 Old
54 212552_at hippocalcin-like 1 HPCAL1 2p25.1 BE617588 65.3 Below 2.6 Old
55 213358_at KIAA0802 protein KIAA0802 18p11.21 AB018345.1 65.3 Above 12.7 Old
56 222699_s_at phafin 2 FLJ13187 8q21.3 BF439250 65.3 Above 3.5 New
57 225618_at EST   17 AI769587 65.3 Below 5.3 New
58 238778_at DKFZp451L157 DKFZp451L157 10 AI244661 65.3 Above 23.5 New
59 239427_at ESTs   1 AA131524 65.3 Above 13.7 New
60 47069_at Rho GTPase activating protein 8 ARHGAP8 22q13.31 AA533284 65.3 Above 3.3 New
61 205769_at solute carrier family 27 (fatty acid transporter), member 2 SLC27A2 15q21.2 NM_003645.1 65.1 Above 56.0 Old
62 210786_s_at Friend leukemia virus integration 1 FLI1 11q24.1-q24.3 M93255.1 65.1 Above 2.2 Old
63 212985_at DKFZp434E033 DKFZp434E033 4 BF115739 65.1 Above 7.1 New
64 227441_s_at E2a-Pbx1-associated protein EB-1 12 AW005572 65.1 Above 1139.4 New
65 234261_at DKFZp761M10121 DKFZp761M10121 12 AL137313.1 65.1 Above 960.8 New
66 244565_at ESTs   10 AI685824 65.1 Above 7.6 New
67 202181_at KIAA0247 gene product KIAA0247 14q24.1 NM_014734.1 63.7 Above 1.8 Old
68 202207_at ADP-ribosylation factor-like 7 ARL7 2q37.2 NM_005737.2 63.7 Above 3.2 Old
69 207571_x_at basement membrane-induced gene ICB-1 1p35.3 NM_004848.1 63.7 Below 4.4 Old
70 209558_s_at huntingtin interacting protein 12 HIP12 12q24 AB013384.1 61.1 Above 23.8 Old
71 213005_s_at KIAA0172 protein KIAA0172 9p24.3 D79994.1 61.1 Above 8.3 Old
72 236854_at cDNA DKFZp667F0617 DKFZp667F0617 20 AA743694 61.1 Above 12.6 New
73 226233_at tubulin-specific chaperone e TBCE 1q42.3 BG112197 60.0 Above 2.6 New
74 203435_s_at membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) MME 3q25.1-q25.2 NM_007287.1 59.9 Below 2.2 Old
75 202478_at GS3955 protein GS3955 2p25.1 NM_021643.1 59.3 Above 4.0 Old
76 202479_s_at GS3955 protein GS3955 2p25.1 BC002637.1 59.3 Above 3.3 Old
77 203999_at synaptotagmin I SYT1 12cen-q21 NM_005639.1 59.3 Above 3.9 Old
78 212149_at KIAA0143 protein KIAA0143 8q24.12 AA805651 59.3 Below 13.5 New
79 212873_at minor histocompatibility antigen HA-1 HA-1 19p13.3 BE349017 59.3 Below 2.9 Old
80 218346_s_at p53 regulated PA26 nuclear protein PA26 6q21 NM_014454.1 59.3 Below 4.7 New
81 224856_at FK506 binding protein 5 FKBP5 6p21.3-21.2 AL122066.1 59.3 Below 5.5 Old
82 200811_at cold inducible RNA binding protein CIRBP 19p13.3 NM_001280.1 59.1 Below 5.8 Old
83 201722_s_at UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) GALNT1 18q12.1 NM_020474.2 59.1 Below 1.8 New
84 223711_s_at HSPC144 protein HSPC144 11q25 AF182413.1 59.1 Above 2.0 New
85 233273_at cDNA FLJ12010 fis FLJ12010 1 AU146834 59.1 Above 30.6 New
86 201460_at mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 1q32 AI141802 57.9 Above 2.1 Old
87 202421_at immunoglobulin superfamily, member 3 IGSF3 1p13 AB007935.1 57.9 Above 4.4 New
88 217983_s_at ribonuclease 6 precursor RNASE6PL 6q27 NM_003730.2 57.9 Below 3.4 New
89 218087_s_at sorbin and SH3 domain containing 1 SORBS1 10q23.3-q24.1 NM_015385.1 57.9 Above 25.1 New
90 218491_s_at HSPC144 protein HSPC144 11q25 NM_014174.1 57.9 Above 1.4 New
91 201825_s_at CGI-49 protein LOC51097 1q44 AL572542 57.8 Above 2.2 Old
92 202206_at ADP-ribosylation factor-like 7 ARL7 2q37.2 NM_005737.2 57.8 Above 3.9 Old
93 218683_at polypyrimidine tract binding protein 2 PTBP2 1p22.11-p21.3 NM_021190.1 57.8 Above 1.8 New
94 226590_at cDNA clone EUROIMAGE 1517766   9 AA031404 57.8 Above 3.1 New
95 227440_at E2a-Pbx1-associated protein EB-1 12 AW005572 57.8 Above 1168.9 New
96 229770_at hypothetical protein FLJ31978 FLJ31978 12q24.33 AI041543 57.8 Above 51.8 New
97 40148_at amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) APBB2 4p14 U62325 57.8 Above 6.2 Old
98 212959_s_at MGC4170 protein MGC4170 12q23.1 AK001821.1 57.2 Below 3.0 New
99 203143_s_at KIAA0040 gene product KIAA0040 1q24-25 T79953 56.3 Above 2.4 New
100 209683_at hypothetical protein DKFZp566A1524 DKFZP566A1524 2p24.2 AA243659 56.3 Below 10.0 New

Table S4. Top 100 chi-square probe sets selected for E2A-PBX1 in decision tree format

  U133
probe set
Gene description Symbol Location GenBank Reference Chi-square value E2A PBX1
above/below
mean
Fold change old or new
1 201579_at FAT tumor suppressor homolog 1 (Drosophila) FAT 4q34-q35 NM_005245.1 88.0 Above 9.9 old
2 201695_s_at nucleoside phosphorylase NP 14q13.1 NM_000270.1 88.0 Above 3.8 old
3 204674_at lymphoid-restricted membrane protein LRMP 12p12.3 NM_006152.1 88.0 Above 5.8 old
4 205253_at pre-B-cell leukemia transcription factor 1 PBX1 1q23 NM_002585.1 88.0 Above 3549.2 old
5 212148_at pre-B-cell leukemia transcription factor 1, splice variant PBX1 1q23 BF967998 88.0 Above 5283.5 old
6 212151_at pre-B-cell leukemia transcription factor 1, splice variant PBX1 1q23 BF967998 88.0 Above 7472.2 old
7 212371_at DKFZp586C1019 DKFZp586C1019 1 AL049397.1 88.0 Above 2.5 old
8 219155_at retinal degeneration B beta RDGBB 17q24.2 NM_012417.1 88.0 Above 2.7 new
9 225483_at hypothetical protein MGC10485 MGC10485 11q25 AI971602 88.0 Above 7.7 new
10 227439_at E2a-Pbx1-associated protein EB-1 12 AW005572 88.0 Above 269.8 new
11 227949_at Q9H4T4 like H17739 20q13.32 AL357503 88.0 Above 59.3 new
12 230306_at hypothetical protein MGC10485 MGC10485 11q25 AA514326 88.0 Above 19.2 new
13 231095_at retinal degeneration B beta RDGBB 17q24.2 AW193811 88.0 Above 25.6 new
14 203372_s_at STAT induced STAT inhibitor-2 SOCS2 12q AB004903.1 80.6 Below 23.4 old
15 206028_s_at c-mer proto-oncogene tyrosine kinase MERTK 2q14.1 NM_006343.1 80.6 Above 23.7 old
16 206181_at signaling lymphocytic activation molecule SLAM 1q22-q23 NM_003037.1 80.6 Above 6.3 old
17 208788_at homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2 HELO1 6p21.1-p12.1 AL136939.1 80.6 Above 2.2 old
18 209760_at KIAA0922 protein KIAA0922 4q31.23 AL136932.1 80.6 Above 2.9 old
19 35974_at lymphoid-restricted membrane protein LRMP 12p12.3 U10485 80.6 Above 6.2 old
20 38340_at huntingtin interacting protein 12 HIP12 12q24 AB014555 80.6 Above 3.8 old
21 208644_at ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) ADPRT 1q41-q42 M32721.1 80.2 Above 3.0 old
22 212789_at KIAA0056 protein KIAA0056 11q25 AI796581 80.2 Above 3.9 old
23 221113_s_at wingless-type MMTV integration site family, member 16 WNT16 7q31 NM_016087.1 80.2 Above 2547.6 new
24 224022_x_at wingless-type MMTV integration site family, member 16 WNT16 7q31 AF169963.1 80.2 Above 569.1 new
25 231040_at EST   9 AW512988 80.2 Above 16.4 new
26 232289_at FLJ14167 FLJ14167 17 BF237871 80.2 Above 144.1 new
27 235666_at EST FLJ20489 10 AA903473 80.2 Above 654.6 new
28 203373_at STAT induced STAT inhibitor-2 SOCS2 12q NM_003877.1 74.2 Below 24.8 old
29 210785_s_at basement membrane-induced gene ICB-1 1p35.3 AB035482.1 74.2 Below 4.1 old
30 224733_at chemokine-like factor super family 3 CKLFSF3 16q23.1 AL574900 74.2 Below 41.7 new
31 225235_at hypothetical protein MGC14859 MGC14859 5q35.3 AW007710 74.2 Above 3.6 new
32 204114_at nidogen 2 (osteonidogen) NID2 14q21-q22 NM_007361.1 73.1 Above 15.1 old
33 211913_s_at c-mer proto-oncogene tyrosine kinase MERTK 2q14.1 L08961.1 72.8 Above 37.7 old
34 219551_at uncharacterized bone marrow protein BM040 BM040 3q21.1 NM_018456.1 72.8 Above 3.0 New
35 223693_s_at hypothetical protein FLJ10324 FLJ10324 7p22 AL136731.1 72.8 Above 65.6 New
36 200600_at moesin MSN Xq11.2-q12 NM_002444.1 72.5 Below 2.2 Old
37 213909_at FLJ12280 FLJ12280 3 AU147799 72.5 Above 12.5 New
38 221669_s_at acyl-Coenzyme A dehydrogenase family, member 8 ACAD8 11q25 BC001964.1 72.5 Above 2.6 New
39 235911_at ESTs, Weakly similar to PIHUB6 salivary proline-rich protein precursor PRB1 (large allele)   3 AI885815 72.5 Above 36.6 New
40 243533_x_at ESTs     H09663 72.5 Above 23.2 New
41 202615_at DKFZp686D0521 DKFZp686D0521 9 BF222895 68.6 Below 6.2 Old
42 204774_at ecotropic viral integration site 2A EVI2A 17q11.2 NM_014210.1 68.6 Below 3.0 New
43 218283_at synovial sarcoma translocation gene on chromosome 18-like 2 SS18L2 3p21 NM_016305.1 68.6 Above 1.6 New
44 209130_at synaptosomal-associated protein, 23kDa SNAP23 15q14 BC003686.1 67.8 Below 1.9 New
45 228580_at serine protease HTRA3 HTRA3 4p16.1 AI828007 66.6 Above 3.8 New
46 202796_at synaptopodin KIAA1029 5q33.1 NM_007286.1 66.5 Above 52.3 Old
47 218640_s_at phafin 2 FLJ13187 8q21.3 NM_024613.1 66.5 Above 3.1 New
48 235099_at ESTs, Weakly similar to PLLP_HUMAN Plasmolipin [H.sapiens]   3 AW080832 66.5 Above 6.7 New
49 201889_at family with sequence similarity 3, member C FAM3C 7q22.1-q31.1 NM_014888.1 65.3 Above 4.6 New
50 202106_at golgi autoantigen, golgin subfamily a, 3 GOLGA3 12q24.33 NM_005895.1 65.3 Above 3.3 Old
51 202208_s_at ADP-ribosylation factor-like 7 ARL7 2q37.2 BC001051.1 65.3 Above 3.2 Old
52 205173_x_at CD58 antigen, (lymphocyte function-associated antigen 3) CD58 1p13 NM_001779.1 65.3 Above 2.4 Old
53 211744_s_at CD58 antigen, (lymphocyte function-associated antigen 3) CD58 1p13 BC005930.1 65.3 Above 2.5 Old
54 212552_at hippocalcin-like 1 HPCAL1 2p25.1 BE617588 65.3 Below 2.6 Old
55 213358_at KIAA0802 protein KIAA0802 18p11.21 AB018345.1 65.3 Above 12.7 Old
56 222699_s_at phafin 2 FLJ13187 8q21.3 BF439250 65.3 Above 3.5 New
57 225618_at EST   17 AI769587 65.3 Below 5.3 New
58 238778_at DKFZp451L157 DKFZp451L157 10 AI244661 65.3 Above 23.5 New
59 239427_at ESTs   1 AA131524 65.3 Above 13.7 New
60 47069_at Rho GTPase activating protein 8 ARHGAP8 22q13.31 AA533284 65.3 Above 3.3 New
61 205769_at solute carrier family 27 (fatty acid transporter), member 2 SLC27A2 15q21.2 NM_003645.1 65.1 Above 56.0 Old
62 210786_s_at Friend leukemia virus integration 1 FLI1 11q24.1-q24.3 M93255.1 65.1 Above 2.2 Old
63 212985_at DKFZp434E033 DKFZp434E033 4 BF115739 65.1 Above 7.1 New
64 227441_s_at E2a-Pbx1-associated protein EB-1 12 AW005572 65.1 Above 1139.4 New
65 234261_at DKFZp761M10121 DKFZp761M10121 12 AL137313.1 65.1 Above 960.8 New
66 244565_at ESTs   10 AI685824 65.1 Above 7.6 New
67 202181_at KIAA0247 gene product KIAA0247 14q24.1 NM_014734.1 63.7 Above 1.8 Old
68 202207_at ADP-ribosylation factor-like 7 ARL7 2q37.2 NM_005737.2 63.7 Above 3.2 Old
69 207571_x_at basement membrane-induced gene ICB-1 1p35.3 NM_004848.1 63.7 Below 4.4 Old
70 209558_s_at huntingtin interacting protein 12 HIP12 12q24 AB013384.1 61.1 Above 23.8 Old
71 213005_s_at KIAA0172 protein KIAA0172 9p24.3 D79994.1 61.1 Above 8.3 Old
72 236854_at cDNA DKFZp667F0617 DKFZp667F0617 20 AA743694 61.1 Above 12.6 New
73 226233_at tubulin-specific chaperone e TBCE 1q42.3 BG112197 60.0 Above 2.6 New
74 203435_s_at membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) MME 3q25.1-q25.2 NM_007287.1 59.9 Below 2.2 Old
75 202478_at GS3955 protein GS3955 2p25.1 NM_021643.1 59.3 Above 4.0 Old
76 202479_s_at GS3955 protein GS3955 2p25.1 BC002637.1 59.3 Above 3.3 Old
77 203999_at synaptotagmin I SYT1 12cen-q21 NM_005639.1 59.3 Above 3.9 Old
78 212149_at KIAA0143 protein KIAA0143 8q24.12 AA805651 59.3 Below 13.5 New
79 212873_at minor histocompatibility antigen HA-1 HA-1 19p13.3 BE349017 59.3 Below 2.9 Old
80 218346_s_at p53 regulated PA26 nuclear protein PA26 6q21 NM_014454.1 59.3 Below 4.7 New
81 224856_at FK506 binding protein 5 FKBP5 6p21.3-21.2 AL122066.1 59.3 Below 5.5 Old
82 200811_at cold inducible RNA binding protein CIRBP 19p13.3 NM_001280.1 59.1 Below 5.8 Old
83 201722_s_at UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) GALNT1 18q12.1 NM_020474.2 59.1 Below 1.8 New
84 223711_s_at HSPC144 protein HSPC144 11q25 AF182413.1 59.1 Above 2.0 New
85 233273_at cDNA FLJ12010 fis FLJ12010 1 AU146834 59.1 Above 30.6 New
86 201460_at mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 1q32 AI141802 57.9 Above 2.1 Old
87 202421_at immunoglobulin superfamily, member 3 IGSF3 1p13 AB007935.1 57.9 Above 4.4 New
88 217983_s_at ribonuclease 6 precursor RNASE6PL 6q27 NM_003730.2 57.9 Below 3.4 New
89 218087_s_at sorbin and SH3 domain containing 1 SORBS1 10q23.3-q24.1 NM_015385.1 57.9 Above 25.1 New
90 218491_s_at HSPC144 protein HSPC144 11q25 NM_014174.1 57.9 Above 1.4 New
91 201825_s_at CGI-49 protein LOC51097 1q44 AL572542 57.8 Above 2.2 Old
92 202206_at ADP-ribosylation factor-like 7 ARL7 2q37.2 NM_005737.2 57.8 Above 3.9 Old
93 218683_at polypyrimidine tract binding protein 2 PTBP2 1p22.11-p21.3 NM_021190.1 57.8 Above 1.8 New
94 226590_at cDNA clone EUROIMAGE 1517766   9 AA031404 57.8 Above 3.1 New
95 227440_at E2a-Pbx1-associated protein EB-1 12 AW005572 57.8 Above 1168.9 New
96 229770_at hypothetical protein FLJ31978 FLJ31978 12q24.33 AI041543 57.8 Above 51.8 New
97 40148_at amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) APBB2 4p14 U62325 57.8 Above 6.2 Old
98 212959_s_at MGC4170 protein MGC4170 12q23.1 AK001821.1 57.2 Below 3.0 New
99 203143_s_at KIAA0040 gene product KIAA0040 1q24-25 T79953 56.3 Above 2.4 New
100 209683_at hypothetical protein DKFZp566A1524 DKFZP566A1524 2p24.2 AA243659 56.3 Below 10.0 New

Section III continued...