St. Jude Research

Molecular Profiler (v1.5) Summary

Profile Name: Annotated Hit List

Profile Date: 21:48 10.1.2006

Molecule Count: 48

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Probe ID Activity RawData PFlag Indicates failure in any of the following criteria: 1. Low plate Z-prime, 2. Low plate Z-factor, 3. Abnormally high % activity, 4. Low PSCORE (Weighted sum of the Bioactive, Toxicity, Available, and ADME scores; positive values are favorable: they are indicative of molecules which have a prior history of bioactivity, low toxicity, high availability, and/or high bioavailability). Records sorted by number of pflags, then percent activity Bioactive Results from a similarity search against a database of known bioactive molecules; the score is the number of unique hits. Toxicity Results from a similarity search against a database of compounds with genotoxicity and cytotoxicity data; the score is the sum of compounds with all negative test results (+1 each), at least one inconclusive test (-0.25), and one or more positive test results (-1 each) Available Results from a similarity search against a database of commercially available molecules; the score is the number of unique hits ADME Results from the application of the ADME Profiler; the score is the sum of the following: REOS violation (-1.0 each), IP and AS model failures (-0.5 each), Lipinski, Oprea, and Ghose violations (-0.25 each), and Suspect Feature and Miscellanous violations (-0.1 each)
1
IDNM:
AB-00130652 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01829MS,G07 Location info: plateid, well
Click HERE For History
%Activ:
100.23 (3.92) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.67 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.17 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1383 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
1.00
NumDrugHits:
9
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
1
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
5
Click HERE For Hits
ADMEScore:
-2.75
ADMEViols:
2
Click HERE For Hits
2
IDNM:
AB-00130828 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01832MS,A06 Location info: plateid, well
Click HERE For History
%Activ:
100.20 (3.92) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.57 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.43 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1014 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
1.00
NumDrugHits:
7
Click HERE For Hits
ToxScore:
-0.89
NumToxHits:
9
Click HERE For Hits
AvailScore:
3.00
NumAvailHits:
6
Click HERE For Hits
ADMEScore:
-4.00
ADMEViols:
4
Click HERE For Hits
4
IDNM:
AB-00131556 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01841MS,D11 Location info: plateid, well
Click HERE For History
%Activ:
100.00 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.52 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.20 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
971 Fluorescence intensity
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Failed 0 of 4 Flags
DrugScore:
7.00
NumDrugHits:
12
Click HERE For Hits
ToxScore:
-2.00
NumToxHits:
2
Click HERE For Hits
AvailScore:
7.00
NumAvailHits:
11
Click HERE For Hits
ADMEScore:
-6.25
ADMEViols:
6
Click HERE For Hits
5
IDNM:
AB-00131576 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01841MS,F11 Location info: plateid, well
Click HERE For History
%Activ:
99.99 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.52 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.20 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
992 Fluorescence intensity
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Failed 0 of 4 Flags
DrugScore:
57.00
NumDrugHits:
69
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ToxScore:
-13.30
NumToxHits:
15
Click HERE For Hits
AvailScore:
5.00
NumAvailHits:
9
Click HERE For Hits
ADMEScore:
-8.00
ADMEViols:
8
Click HERE For Hits
7
IDNM:
AB-00130652 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01845MS,D03 Location info: plateid, well
Click HERE For History
%Activ:
99.99 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
-0.06 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
994 Fluorescence intensity
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Failed 0 of 4 Flags
DrugScore:
1.00
NumDrugHits:
9
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
1
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
5
Click HERE For Hits
ADMEScore:
-2.75
ADMEViols:
2
Click HERE For Hits
8
IDNM:
AB-00130490 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01846MS,D07 Location info: plateid, well
Click HERE For History
%Activ:
99.98 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.03 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1184 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
2.00
NumDrugHits:
7
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
1
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
3
Click HERE For Hits
ADMEScore:
-1.50
ADMEViols:
1
Click HERE For Hits
10
IDNM:
AB-00130956 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01845MS,D07 Location info: plateid, well
Click HERE For History
%Activ:
99.97 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
-0.06 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1126 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
5.00
NumDrugHits:
10
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
3
Click HERE For Hits
AvailScore:
21.00
NumAvailHits:
37
Click HERE For Hits
ADMEScore:
-1.00
ADMEViols:
1
Click HERE For Hits
9
IDNM:
AB-00130956 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01833MS,G02 Location info: plateid, well
Click HERE For History
%Activ:
99.97 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.72 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.41 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1552 Fluorescence intensity
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Failed 0 of 4 Flags
DrugScore:
5.00
NumDrugHits:
10
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
3
Click HERE For Hits
AvailScore:
21.00
NumAvailHits:
37
Click HERE For Hits
ADMEScore:
-1.00
ADMEViols:
1
Click HERE For Hits
12
IDNM:
AB-00130044 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01822MS,A09 Location info: plateid, well
Click HERE For History
%Activ:
99.96 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.51 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.13 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1120 Fluorescence intensity
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Failed 0 of 4 Flags
DrugScore:
10.00
NumDrugHits:
16
Click HERE For Hits
ToxScore:
-2.00
NumToxHits:
2
Click HERE For Hits
AvailScore:
10.00
NumAvailHits:
15
Click HERE For Hits
ADMEScore:
-5.75
ADMEViols:
5
Click HERE For Hits
11
IDNM:
AB-00131545 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01841MS,C10 Location info: plateid, well
Click HERE For History
%Activ:
99.96 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.52 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.20 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1169 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
3.00
NumDrugHits:
7
Click HERE For Hits
ToxScore:
-3.00
NumToxHits:
3
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
3
Click HERE For Hits
ADMEScore:
-3.75
ADMEViols:
3
Click HERE For Hits
13
IDNM:
AB-00131712 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01845MS,E08 Location info: plateid, well
Click HERE For History
%Activ:
99.95 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
-0.06 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1178 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
7.00
NumDrugHits:
8
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
4
Click HERE For Hits
AvailScore:
3.00
NumAvailHits:
5
Click HERE For Hits
ADMEScore:
-2.50
ADMEViols:
2
Click HERE For Hits
14
IDNM:
AB-00130490 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01827MS,G03 Location info: plateid, well
Click HERE For History
%Activ:
99.95 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.64 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.28 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1328 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
2.00
NumDrugHits:
7
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
1
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
3
Click HERE For Hits
ADMEScore:
-1.50
ADMEViols:
1
Click HERE For Hits
15
IDNM:
AB-00131767 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01844MS,B09 Location info: plateid, well
Click HERE For History
%Activ:
99.95 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.44 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.38 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1304 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
3.00
NumDrugHits:
3
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
0
Click HERE For Hits
AvailScore:
4.00
NumAvailHits:
5
Click HERE For Hits
ADMEScore:
-7.00
ADMEViols:
7
Click HERE For Hits
16
IDNM:
AB-00131388 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01839MS,C09 Location info: plateid, well
Click HERE For History
%Activ:
99.90 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.56 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.22 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
1466 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
94.00
NumDrugHits:
100
Click HERE For Hits
ToxScore:
-38.57
NumToxHits:
56
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-6.25
ADMEViols:
6
Click HERE For Hits
18
IDNM:
AB-00131341 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01838MS,F09 Location info: plateid, well
Click HERE For History
%Activ:
99.24 (3.88) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.47 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.36 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
6816 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
20.00
NumDrugHits:
28
Click HERE For Hits
ToxScore:
-0.92
NumToxHits:
13
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-4.00
ADMEViols:
4
Click HERE For Hits
19
IDNM:
AB-00131341 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01846MS,G05 Location info: plateid, well
Click HERE For History
%Activ:
99.01 (3.87) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.03 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
7268 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
20.00
NumDrugHits:
28
Click HERE For Hits
ToxScore:
-0.92
NumToxHits:
13
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-4.00
ADMEViols:
4
Click HERE For Hits
20
IDNM:
AB-00130651 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01829MS,G06 Location info: plateid, well
Click HERE For History
%Activ:
98.88 (3.87) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.67 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.17 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
10699 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
40.00
NumDrugHits:
52
Click HERE For Hits
ToxScore:
7.00
NumToxHits:
8
Click HERE For Hits
AvailScore:
78.00
NumAvailHits:
100
Click HERE For Hits
ADMEScore:
-1.75
ADMEViols:
1
Click HERE For Hits
21
IDNM:
AB-00130651 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01845MS,H05 Location info: plateid, well
Click HERE For History
%Activ:
98.66 (3.86) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
-0.06 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
7688 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
40.00
NumDrugHits:
52
Click HERE For Hits
ToxScore:
7.00
NumToxHits:
8
Click HERE For Hits
AvailScore:
78.00
NumAvailHits:
100
Click HERE For Hits
ADMEScore:
-1.75
ADMEViols:
1
Click HERE For Hits
22
IDNM:
AB-00131712 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01843MS,D11 Location info: plateid, well
Click HERE For History
%Activ:
98.26 (3.84) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.77 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.33 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
9668 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
7.00
NumDrugHits:
8
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
4
Click HERE For Hits
AvailScore:
3.00
NumAvailHits:
5
Click HERE For Hits
ADMEScore:
-2.50
ADMEViols:
2
Click HERE For Hits
23
IDNM:
AB-00129928 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01820MS,E10 Location info: plateid, well
Click HERE For History
%Activ:
97.46 (3.81) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.50 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.22 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
25536 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
2.00
NumDrugHits:
4
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
2
Click HERE For Hits
AvailScore:
3.00
NumAvailHits:
5
Click HERE For Hits
ADMEScore:
-3.75
ADMEViols:
3
Click HERE For Hits
24
IDNM:
AB-00131836 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01846MS,F03 Location info: plateid, well
Click HERE For History
%Activ:
97.28 (3.80) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.03 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
18167 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
20.00
NumDrugHits:
28
Click HERE For Hits
ToxScore:
8.00
NumToxHits:
10
Click HERE For Hits
AvailScore:
4.00
NumAvailHits:
6
Click HERE For Hits
ADMEScore:
-7.50
ADMEViols:
7
Click HERE For Hits
25
IDNM:
AB-00130921 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01833MS,C05 Location info: plateid, well
Click HERE For History
%Activ:
96.57 (3.77) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.72 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.41 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
37024 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
1.00
NumDrugHits:
3
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
1
Click HERE For Hits
AvailScore:
4.00
NumAvailHits:
5
Click HERE For Hits
ADMEScore:
-3.00
ADMEViols:
3
Click HERE For Hits
26
IDNM:
AB-00131503 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01840MS,G06 Location info: plateid, well
Click HERE For History
%Activ:
96.27 (3.76) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.72 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.44 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
24771 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
8.00
NumDrugHits:
8
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
0
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
1
Click HERE For Hits
ADMEScore:
-4.50
ADMEViols:
4
Click HERE For Hits
27
IDNM:
AB-00131387 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01839MS,C08 Location info: plateid, well
Click HERE For History
%Activ:
96.21 (3.76) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.56 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.22 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
26230 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
11.00
NumDrugHits:
14
Click HERE For Hits
ToxScore:
-3.00
NumToxHits:
3
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-1.25
ADMEViols:
1
Click HERE For Hits
28
IDNM:
AB-00131375 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01839MS,B06 Location info: plateid, well
Click HERE For History
%Activ:
94.57 (3.69) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.56 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.22 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
37293 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
11.00
NumDrugHits:
11
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
1
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
2
Click HERE For Hits
ADMEScore:
-9.00
ADMEViols:
9
Click HERE For Hits
29
IDNM:
AB-00129888 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01820MS,A09 Location info: plateid, well
Click HERE For History
%Activ:
93.77 (3.66) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.50 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.22 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
61384 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
1.00
NumDrugHits:
4
Click HERE For Hits
ToxScore:
-1.00
NumToxHits:
2
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
2
Click HERE For Hits
ADMEScore:
-1.75
ADMEViols:
1
Click HERE For Hits
30
IDNM:
AB-00131183 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01836MS,F06 Location info: plateid, well
Click HERE For History
%Activ:
93.73 (3.66) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.63 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.33 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
45906 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
7.00
NumDrugHits:
9
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
0
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
2
Click HERE For Hits
ADMEScore:
-4.50
ADMEViols:
4
Click HERE For Hits
31
IDNM:
AB-00130828 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01846MS,A03 Location info: plateid, well
Click HERE For History
%Activ:
93.70 (3.66) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.03 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
40716 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
1.00
NumDrugHits:
7
Click HERE For Hits
ToxScore:
-0.89
NumToxHits:
9
Click HERE For Hits
AvailScore:
3.00
NumAvailHits:
6
Click HERE For Hits
ADMEScore:
-4.00
ADMEViols:
4
Click HERE For Hits
32
IDNM:
AB-00130585 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01828MS,H09 Location info: plateid, well
Click HERE For History
%Activ:
89.31 (3.48) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.57 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.26 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
90617 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
6.00
NumDrugHits:
11
Click HERE For Hits
ToxScore:
-2.57
NumToxHits:
7
Click HERE For Hits
AvailScore:
4.00
NumAvailHits:
6
Click HERE For Hits
ADMEScore:
-3.25
ADMEViols:
3
Click HERE For Hits
33
IDNM:
AB-00130752 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01831MS,A08 Location info: plateid, well
Click HERE For History
%Activ:
87.57 (3.41) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.34 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.38 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
94308 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
87.00
NumDrugHits:
100
Click HERE For Hits
ToxScore:
-12.42
NumToxHits:
16
Click HERE For Hits
AvailScore:
6.00
NumAvailHits:
10
Click HERE For Hits
ADMEScore:
-7.00
ADMEViols:
7
Click HERE For Hits
34
IDNM:
AB-00131788 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01844MS,D11 Location info: plateid, well
Click HERE For History
%Activ:
86.16 (3.35) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.44 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.38 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
109441 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
75.00
NumDrugHits:
78
Click HERE For Hits
ToxScore:
-0.80
NumToxHits:
5
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
3
Click HERE For Hits
ADMEScore:
-3.25
ADMEViols:
3
Click HERE For Hits
37
IDNM:
AB-00131390 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01839MS,C11 Location info: plateid, well
Click HERE For History
%Activ:
82.58 (3.20) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.56 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.22 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
117763 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
21.00
NumDrugHits:
24
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
0
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
2
Click HERE For Hits
ADMEScore:
-5.50
ADMEViols:
5
Click HERE For Hits
38
IDNM:
AB-00130431 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01827MS,A04 Location info: plateid, well
Click HERE For History
%Activ:
81.43 (3.16) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.64 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.28 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
184677 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
2.00
NumDrugHits:
4
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
0
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-3.25
ADMEViols:
3
Click HERE For Hits
39
IDNM:
AB-00130265 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01846MS,D09 Location info: plateid, well
Click HERE For History
%Activ:
80.33 (3.11) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.03 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
124837 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
48.00
NumDrugHits:
57
Click HERE For Hits
ToxScore:
-10.31
NumToxHits:
12
Click HERE For Hits
AvailScore:
4.00
NumAvailHits:
8
Click HERE For Hits
ADMEScore:
-7.25
ADMEViols:
7
Click HERE For Hits
40
IDNM:
AB-00130739 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01830MS,H05 Location info: plateid, well
Click HERE For History
%Activ:
75.71 (2.92) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.52 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.37 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
185918 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
8.00
NumDrugHits:
11
Click HERE For Hits
ToxScore:
5.00
NumToxHits:
9
Click HERE For Hits
AvailScore:
18.00
NumAvailHits:
30
Click HERE For Hits
ADMEScore:
-3.00
ADMEViols:
3
Click HERE For Hits
41
IDNM:
AB-00130038 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01822MS,A02 Location info: plateid, well
Click HERE For History
%Activ:
75.19 (2.90) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.51 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.13 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
212123 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
9.00
NumDrugHits:
15
Click HERE For Hits
ToxScore:
-0.91
NumToxHits:
11
Click HERE For Hits
AvailScore:
11.00
NumAvailHits:
14
Click HERE For Hits
ADMEScore:
-3.50
ADMEViols:
3
Click HERE For Hits
42
IDNM:
AB-00130752 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01845MS,G03 Location info: plateid, well
Click HERE For History
%Activ:
75.00 (2.89) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
-0.06 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
127041 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
87.00
NumDrugHits:
100
Click HERE For Hits
ToxScore:
-12.42
NumToxHits:
16
Click HERE For Hits
AvailScore:
6.00
NumAvailHits:
10
Click HERE For Hits
ADMEScore:
-7.00
ADMEViols:
7
Click HERE For Hits
43
IDNM:
AB-00130509 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01828MS,A02 Location info: plateid, well
Click HERE For History
%Activ:
66.21 (2.54) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.57 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.26 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
284699 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
10.00
NumDrugHits:
12
Click HERE For Hits
ToxScore:
7.00
NumToxHits:
13
Click HERE For Hits
AvailScore:
6.00
NumAvailHits:
8
Click HERE For Hits
ADMEScore:
-6.50
ADMEViols:
6
Click HERE For Hits
44
IDNM:
AB-00131788 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01845MS,B11 Location info: plateid, well
Click HERE For History
%Activ:
62.29 (2.38) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
-0.06 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
191170 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
75.00
NumDrugHits:
78
Click HERE For Hits
ToxScore:
-0.80
NumToxHits:
5
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
3
Click HERE For Hits
ADMEScore:
-3.25
ADMEViols:
3
Click HERE For Hits
45
IDNM:
AB-00130494 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01827MS,G07 Location info: plateid, well
Click HERE For History
%Activ:
58.13 (2.21) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.64 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.28 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
415293 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
2.00
NumDrugHits:
4
Click HERE For Hits
ToxScore:
4.00
NumToxHits:
4
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
2
Click HERE For Hits
ADMEScore:
-1.50
ADMEViols:
1
Click HERE For Hits
46
IDNM:
AB-00130830 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01845MS,C03 Location info: plateid, well
Click HERE For History
%Activ:
55.40 (2.10) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
-0.06 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
225875 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
68.00
NumDrugHits:
74
Click HERE For Hits
ToxScore:
4.00
NumToxHits:
6
Click HERE For Hits
AvailScore:
3.00
NumAvailHits:
6
Click HERE For Hits
ADMEScore:
-7.25
ADMEViols:
7
Click HERE For Hits
47
IDNM:
AB-00131256 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01837MS,F03 Location info: plateid, well
Click HERE For History
%Activ:
54.40 (2.05) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.86 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.46 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
317361 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
4.00
NumDrugHits:
10
Click HERE For Hits
ToxScore:
-1.67
NumToxHits:
6
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
6
Click HERE For Hits
ADMEScore:
-1.00
ADMEViols:
1
Click HERE For Hits
48
IDNM:
AB-00129926 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01820MS,E08 Location info: plateid, well
Click HERE For History
%Activ:
53.13 (2.00) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.50 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.22 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
456005 Fluorescence intensity
Click HERE For Heatmap
Failed 0 of 4 Flags
DrugScore:
5.00
NumDrugHits:
8
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
0
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-8.75
ADMEViols:
8
Click HERE For Hits
3
IDNM:
AB-00130119 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01845MS,A04 Location info: plateid, well
Click HERE For History
%Activ:
100.01 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
-0.06 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
875 Fluorescence intensity
Click HERE For Heatmap

Low PSCORE

Failed 1 of 4 Flags
DrugScore:
9.00
NumDrugHits:
12
Click HERE For Hits
ToxScore:
-13.50
NumToxHits:
20
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-6.00
ADMEViols:
6
Click HERE For Hits
6
IDNM:
AB-00130119 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01823MS,A04 Location info: plateid, well
Click HERE For History
%Activ:
99.99 (3.91) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.66 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.17 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
937 Fluorescence intensity
Click HERE For Heatmap

Low PSCORE

Failed 1 of 4 Flags
DrugScore:
9.00
NumDrugHits:
12
Click HERE For Hits
ToxScore:
-13.50
NumToxHits:
20
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-6.00
ADMEViols:
6
Click HERE For Hits
17
IDNM:
AB-00129955 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01846MS,F02 Location info: plateid, well
Click HERE For History
%Activ:
99.72 (3.90) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.03 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
2800 Fluorescence intensity
Click HERE For Heatmap

Low PSCORE

Failed 1 of 4 Flags
DrugScore:
3.00
NumDrugHits:
12
Click HERE For Hits
ToxScore:
-5.00
NumToxHits:
5
Click HERE For Hits
AvailScore:
1.00
NumAvailHits:
4
Click HERE For Hits
ADMEScore:
-3.75
ADMEViols:
3
Click HERE For Hits
35
IDNM:
AB-00130116 ABASE unique identifier
Batch:
BATCH-02 Different batches indicate different locations of molecules with the same composition
LOC:
01846MS,G03 Location info: plateid, well
Click HERE For History
%Activ:
83.84 (3.25) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.76 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.03 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
102701 Fluorescence intensity
Click HERE For Heatmap

Low PSCORE

Failed 1 of 4 Flags
DrugScore:
1.00
NumDrugHits:
6
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
0
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
3
Click HERE For Hits
ADMEScore:
-7.75
ADMEViols:
7
Click HERE For Hits
36
IDNM:
AB-00130116 ABASE unique identifier
Batch:
BATCH-01 Different batches indicate different locations of molecules with the same composition
LOC:
01822MS,H11 Location info: plateid, well
Click HERE For History
%Activ:
82.78 (3.21) Percent activity relative to the positive control on the plate, and (ZSCORE), the distance in standard deviations from mean assay activity
ZPrime:
0.51 A measure of discrimination between positive and negative controls in the screen: zprime < 0.0 indicates a failed assay, 0.0 < zprime < 0.5 indicates that the assay discriminates between positive and negative controls, and 0.5 < zprime < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
ZFactor:
0.13 A measure of discrimination between positive controls and the compounds in the screen: zfactor < 0.0 indicates a failed assay, 0.0 < zfactor < 0.5 indicates that the assay discriminates between actives and inactives, and 0.5 < zfactor < 1.0 is ideal (see Zhang, J.BioScreening, 1999)
Click HERE For SAR
FINT:
147445 Fluorescence intensity
Click HERE For Heatmap

Low PSCORE

Failed 1 of 4 Flags
DrugScore:
1.00
NumDrugHits:
6
Click HERE For Hits
ToxScore:
0.00
NumToxHits:
0
Click HERE For Hits
AvailScore:
2.00
NumAvailHits:
3
Click HERE For Hits
ADMEScore:
-7.75
ADMEViols:
7
Click HERE For Hits