Supplementary Files for Reed et al, Journal of Biological Chemistry, 2009
Each URL below links to the HTS screening report (RISE report) for a particular assay.
human MDM2 Dose-Response assay
mouse MDMX Dose-Response assay
human BJ cytotoxicity assay
human HepG2 cytotoxicity assay Download structure and assay data in SDF format:
SDF for 1152 compounds with DR data (gzipped)
Definitions for the SDF property fields Summary data for exemplar compound SJ000172550:
- Click the "Endpoint Analysis" link in the "Quality Control Assessment" section of the RISE report to view assay QC metrics
- Click the "Model Summary" link in the "Assay Activity Summary" section of the RISE report to view DR curves for Reference/Controls and Screening (Variable) compounds. Variable compounds are grouped into curve classes according to dose-response curve shape and fitting statistics.
human MDM2 Dose-Response assay
mouse MDMX Dose-Response assay
human BJ cytotoxicity assay
human HepG2 cytotoxicity assay Download structure and assay data in SDF format:
SDF for 1152 compounds with DR data (gzipped)
Definitions for the SDF property fields Summary data for exemplar compound SJ000172550:
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