Appendix 1. Genes marked with "X" do not meet the criteria established for microarray
analysis of gene expression
Name ID Blood CSF ECC
Conserved hypothetical protein NTL02SP0067
Transporter, truncation NTL02SP0105
Hypothetical protein NTL02SP0107
Conserved hypothetical protein NTL02SP0108
Hypothetical protein NTL02SP0225
The type 2 capsule locus of Streptococcus pneumoniae NTL02SP0315
The type 2 capsule locus of Streptococcus pneumoniae NTL02SP0316
The type 2 capsule locus of Streptococcus pneumoniae NTL02SP0317
The type 2 capsule locus of Streptococcus pneumoniae NTL02SP0319
Ribonuclease P - RNA component NTL02SP0332.1
Hypothetical protein NTL02SP0419
Hypothetical protein NTL02SP0491
Hypothetical protein NTL02SP0703
Hypothetical protein NTL02SP0955
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase NTL02SP0961
Conserved hypothetical protein NTL02SP0962
Hypothetical protein NTL02SP0963
Hypothetical protein NTL02SP0965
Conserved hypothetical protein NTL02SP0967
Hypothetical protein NTL02SP0968
Nikkomycin biosynthesis protein, carboxylase NTL02SP0969
Conserved hypothetical protein NTL02SP0970
Conserved hypothetical protein NTL02SP0972
Hypothetical protein NTL02SP1026
Conserved hypothetical protein NTL02SP1178
Cytidine deaminase NTL02SP1187
Conserved hypothetical protein NTL02SP1188
Hypothetical protein NTL02SP1189
ABC transporter membrane-spanning permease NTL02SP1191
ABC transporter substrate-binding protein NTL02SP1193
Conserved hypothetical protein NTL02SP1194
Hypothetical protein NTL02SP1212
Hypothetical protein NTL02SP1402
Hypothetical protein NTL02SP1480
Hypothetical protein NTL02SP1483
Hypothetical protein NTL02SP1548
Conserved hypothetical protein NTL02SP1549
chromosomal replication initiator protein DnaA SP0001
DNA polymerase III, beta subunit SP0002
hypothetical protein SP0003 X X X
GTP-binding protein SP0004
peptidyl-tRNA hydrolase SP0005
transcription-repair coupling factor SP0006 X
S4 domain protein SP0007
hypothetical protein SP0008
hypothetical protein SP0009 X
conserved domain protein SP0010 X
MesJ/Ycf62 family protein SP0011
hypoxanthine-guanine phosphoribosyltransferase SP0012
cell division protein FtsH SP0013
transcriptional regulator ComX1 SP0014
IS630-Spn1, transposase Orf1 SP0015
IS630-Spn1, transposase Orf2 SP0016
IS1167, transposase, degenerate SP0017 X
hypothetical protein SP0018 X
adenylosuccinate synthetase SP0019
cytidine/deoxycytidylate deaminase family protein SP0020 X
deoxyuridine 5triphosphate nucleotidohydrolase, putative SP0021
conserved hypothetical protein SP0022 X X
DNA repair protein RadA, authentic point mutation SP0023 X X
conserved hypothetical protein SP0024
hypothetical protein SP0025
hypothetical protein SP0026
ribose-phosphate pyrophosphokinase SP0027
IS1167, transposase, truncation SP0028 X X
IS1167, transposase, truncation SP0028 X X
hypothetical protein SP0029 X X
competence-induced protein Ccs16 SP0030 X X
hypothetical protein SP0031 X
DNA polymerase I SP0032
conserved hypothetical protein SP0033
membrane protein SP0034
aromatic amino acid aminotransferase SP0035
conserved hypothetical protein SP0036
fatty acid/phospholipid synthesis protein PlsX SP0037
acyl carrier protein, putative SP0038
IS1381, transposase OrfB, truncation SP0039 X
bacteriocin BlpU SP0041
competence factor transporting ATP-binding/permease protein CoSP0042
competence factor transport protein ComB SP0043
phosphoribosylaminoimidazole-succinocarboxamide synthase SP0044 X
phosphoribosylformylglycinamidine synthase, putative SP0045 X
amidophosphoribosyltransferase SP0046 X
phosphoribosylformylglycinamide cyclo-ligase SP0047 X
phosphoribosylglycinamide formyltransferase SP0048 X
vanZ protein, putative SP0049 X X X
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP SP0050 X
phosphoribosylamine--glycine ligase SP0051 X
phosphoribosylaminoimidazole carboxylase, catalytic subunit SP0053 X
phosphoribosylaminoimidazole carboxylase, ATPase subunit SP0054
hypothetical protein SP0055 X
adenylosuccinate lyase SP0056
beta-N-acetylhexosaminidase SP0057 X
transcriptional regulator, GntR family SP0058
beta-galactosidase SP0060 X X X
PTS system, IIB component SP0061 X X X
PTS system, IIC component SP0062 X X X
PTS system, IID component SP0063 X X X
PTS system, IIA component SP0064 X X X
sugar isomerase domain protein AgaS SP0065 X X X
aldose 1-epimerase SP0066 X X X
hypothetical protein SP0067 X X X
hypothetical protein SP0068 X X X
choline binding protein I SP0069 X X X
immunoglobulin A1 protease SP0071 X X X
conserved hypothetical protein SP0073 X X X
acetyltransferase, CysE/LacA/LpxA/NodL family SP0074 X X X
phosphorylase, Pnp/Udp family SP0075
hypothetical protein SP0077 X X X
potassium uptake protein, Trk family SP0078
potassium uptake protein, Trk family SP0079
glycosyl transferase, family 2, authentic point mutation SP0081
cell wall surface anchor family protein SP0082 X X X
DNA-binding response regulator SP0083 X
sensor histidine kinase SP0084
ribosomal protein S4 SP0085
IS630-Spn1, transposase Orf1, truncation SP0086
hypothetical protein SP0087 X X X
hypothetical protein SP0088
ABC transporter, permease protein SP0090 X X X
ABC transporter, permease protein SP0091 X X X
ABC transporter, substrate-binding protein SP0092 X X X
hypothetical protein SP0093 X X X
hypothetical protein SP0094 X X X
conserved hypothetical protein SP0095
hypothetical protein SP0096 X X X
conserved domain protein SP0097
hypothetical protein SP0098
hypothetical protein SP0099 X X X
conserved hypothetical protein SP0100 X X X
conserved hypothetical protein SP0101
glycosyl transferase SP0102
capsular polysaccharide biosynthesis protein, putative SP0103
hydrolase, haloacid dehalogenase-like family SP0104
L-serine dehydratase, iron-sulfur-dependent, alpha subunit SP0105
L-serine dehydratase, iron-sulfur-dependent, beta subunit SP0106 X
LysM domain protein SP0107
hypothetical protein SP0108 X
bacteriocin, putative SP0109 X X X
hypothetical protein SP0110 X
amino acid ABC transporter, ATP-binding protein, putative SP0111
amino acid ABC transporter, periplasmic amino acid-binding proSP0112 X X X
argininosuccinate synthase, truncation SP0113 X
hypothetical protein SP0114 X X X
hypothetical protein SP0115 X
hypothetical protein SP0116 X X X
pneumococcal surface protein A SP0117
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase SP0118
MutT/nudix family protein SP0119
glucose-inhibited division protein A SP0120
metallo-beta-lactamase superfamily protein SP0121
conserved hypothetical protein SP0122
competence-induced protein Ccs1 SP0123 X X X
hypothetical protein SP0124 X X X
hypothetical protein SP0125 X X X
conserved hypothetical protein SP0127
ribosomal-protein-alanine acetyltransferase, putative SP0128
glycoprotease family protein SP0129
IS1167, transposase, degenerate SP0130 X
IS630-Spn1, transposase Orf2 SP0131 X
IS630-Spn1, transposase Orf1, degenerate SP0132 X X X
hypothetical protein SP0133 X X X
hypothetical protein SP0134 X
glycosyl transferase, putative SP0135 X
glycosyl transferase, family 2 SP0136 X X X
ABC transporter, ATP-binding protein SP0137 X
hypothetical protein SP0138 X X X
conserved domain protein SP0139 X X X
UDP-glucose 6-dehydrogenase, authentic frameshift SP0140 X X X
transcriptional regulator SP0141
hypothetical protein SP0142 X
conserved domain protein SP0143
hypothetical protein SP0144
conserved hypothetical protein SP0145 X
conserved hypothetical protein SP0146 X X X
hypothetical protein SP0147 X X X
ABC transporter, substrate-binding protein SP0148
lipoprotein SP0149
peptidase, M20/M25/M40 family SP0150 X
ABC transporter, ATP-binding protein SP0151
ABC transporter, permease protein, putative SP0152 X
hypothetical protein SP0153 X
hypothetical protein SP0154
sensor histidine kinase, putative SP0155 X
DNA-binding response regulator SP0156
hypothetical protein SP0157
NrdI family protein SP0158
conserved hypothetical protein SP0159
conserved domain protein SP0160 X X
conserved domain protein SP0161 X X
transcriptional regulator PlcR, putative SP0163 X X X
hypothetical protein SP0164 X X X
flavoprotein SP0165 X X X
pyridoxal-dependent decarboxylase, Orn/Lys/Arg family SP0166 X X X
hypothetical protein SP0167 X X X
macrolide efflux protein, putative SP0168 X X X
lactose phosphotransferase system repressor, degenerate SP0169 X X X
ROK family protein SP0171 X X X
DNA mismatch repair protein HexB SP0173
riboflavin synthase, beta subunit SP0175
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolaSP0176
riboflavin synthase, alpha subunit SP0177
riboflavin biosynthesis protein RibD SP0178
Holliday junction DNA helicase RuvA SP0179
DNA-3-methyladenine glycosylase I SP0180 X
conserved hypothetical protein SP0181 X X X
MccC family protein SP0182 X
hypothetical protein SP0184
magnesium transporter, CorA family SP0185
excinuclease ABC, subunit A SP0186
peptidase M24 family protein SP0187
conserved hypothetical protein SP0189
hypothetical protein SP0191
conserved hypothetical protein SP0192
conserved hypothetical protein, authentic frameshift SP0193
conserved hypothetical protein SP0194
dihydrofolate synthetase, putative SP0197 X
hypothetical protein SP0198
cardiolipin synthetase SP0199
competence-induced protein Ccs4 SP0200
hypothetical protein SP0201
anaerobic ribonucleoside-triphosphate reductase SP0202
acetyltransferase, GNAT family SP0204
anaerobic ribonucleoside-triphosphate reductase activating proSP0205 X
hypothetical protein SP0206 X
conserved domain protein SP0207 X
ribosomal protein S10 SP0208
ribosomal protein L3 SP0209
ribosomal protein L4 SP0210
ribosomal protein L23 SP0211
ribosomal protein L2 SP0212
ribosomal protein S19 SP0213
ribosomal protein L22 SP0214
ribosomal protein S3 SP0215
ribosomal protein L16 SP0216
ribosomal protein L29 SP0217
ribosomal protein S17 SP0218
ribosomal protein L14 SP0219
ribosomal protein L24 SP0220
ribosomal protein L5 SP0221
ribosomal protein S14 SP0222
ribosomal protein S8 SP0224
ribosomal protein L6 SP0225
ribosomal protein L18 SP0226
ribosomal protein S5 SP0227
ribosomal protein L30 SP0228
ribosomal protein L15 SP0229
preprotein translocase, SecY subunit SP0230
adenylate kinase SP0231
translation initiation factor IF-1 SP0232
ribosomal protein L36 SP0233
ribosomal protein S13 SP0234
ribosomal protein S11 SP0235
DNA-directed RNA polymerase, alpha subunit SP0236
ribosomal protein L17 SP0237
ACT domain protein SP0238
conserved hypothetical protein SP0239
phosphoglycerate mutase family protein SP0240
iron ABC transporter, permease protein, degenerate SP0241 X X X
iron ABC transporter, ATP-binding protein SP0242 X X X
iron ABC transporter, iron-binding protein SP0243 X X X
pyruvate formate-lyase-activating enzyme, putative SP0245 X X X
transcriptional regulator, DeoR family SP0246 X
transcriptional regulator SP0247 X X X
PTS system, IIA component SP0248 X X X
PTS system, IIB component SP0249 X X X
PTS system, IIC component SP0250 X X X
formate acetyltransferase, putative SP0251 X X X
transaldolase family protein SP0252 X X X
glycerol dehydrogenase SP0253 X X X
leucyl-tRNA synthetase SP0254
acetyltransferase, GNAT family SP0255
acetyltransferase, GNAT family SP0256 X
group II intron, maturase, degenerate SP0257 X X X
Holliday junction DNA helicase RuvB SP0259
conserved hypothetical protein SP0260
undecaprenyl diphosphate synthase SP0261
phosphatidate cytidylyltransferase SP0262 X
eep protein SP0263
prolyl-tRNA synthetase SP0264
glycosyl hydrolase, family 1 SP0265
glucosamine--fructose-6-phosphate aminotransferase, isomerizinSP0266
oxidoreductase, putative SP0267
alkaline amylopullulanase, putative SP0268 X X X
ribosomal protein S12 SP0271
ribosomal protein S7 SP0272
translation elongation factor G SP0273
DNA polymerase III, alpha subunit, Gram-positive type SP0274
conserved hypothetical protein SP0275 X
conserved hypothetical protein SP0276 X
hypothetical protein SP0277 X
aminopeptidase PepS SP0278
conserved hypothetical protein SP0279
ribosomal small subunit pseudouridine synthase A SP0280
aminopeptidase C SP0281
PTS system, mannose-specific IID component SP0282
PTS system, mannose-specific IIC component SP0283
PTS system, mannose-specific IIAB components SP0284
alcohol dehydrogenase, zinc-containing SP0285
Cof family protein SP0286
xanthine/uracil permease family protein SP0287
conserved hypothetical protein SP0288 X
dihydropteroate synthase SP0289
dihydrofolate synthetase SP0290
GTP cyclohydrolase I SP0291
bifunctional folate synthesis protein SP0292
hypothetical protein SP0293
ribosomal protein L13 SP0294
ribosomal protein S9 SP0295
hypothetical protein SP0296 X X X
hypothetical protein SP0297 X X X
conserved hypothetical protein SP0298 X X X
IS630-Spn1, transposase Orf1 SP0299
IS630-Spn1, transposase Orf2 SP0300
conserved domain protein SP0302 X X X
6-phospho-beta-glucosidase SP0303 X X X
conserved hypothetical protein SP0304 X X X
PTS system, IIB component SP0305 X X X
transcriptional regulator, putative SP0306 X X X
PTS system, IIA component SP0307 X X X
PTS system, IIA component SP0308 X X X
hypothetical protein SP0309 X X X
PTS system, IIC component SP0310 X X X
hypothetical protein SP0311 X X X
glycosyl hydrolase, family 31 SP0312
glutathione peroxidase SP0313 X X X
hyaluronidase SP0314 X X X
IS200S, transposase, interruption SP0315 X X X
4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphoglucoSP0317 X X X
carbohydrate kinase, PfkB family SP0318 X X X
conserved domain protein SP0319 X X X
oxidoreductase, short chain dehydrogenase/reductase family SP0320 X X X
PTS system, IIA component SP0321 X X X
glucuronyl hydrolase SP0322 X X X
PTS system, IIB component SP0323 X X X
PTS system, IIC component SP0324 X X X
PTS system, IID component SP0325 X X X
preprotein translocase, YajC subunit SP0326 X X X
hypothetical protein, interruption SP0327 X X X
IS1380-Spn1, transposase SP0328 X X X
hypothetical protein, interruption SP0329 X X X
sugar binding transcriptional regulator RegR SP0330
hypothetical protein, authentic frameshift SP0331 X X X
hypothetical protein SP0332 X X X
transcriptional regulator, putative SP0333 X X X
yllC protein SP0334
cell division protein FtsL SP0335
penicillin-binding protein 2X SP0336
phospho-N-acetylmuramoyl-pentapeptide-transferase SP0337
ATP-dependent Clp protease, ATP-binding subunit, putative SP0338 X X
group II intron, maturase, truncation SP0339 X X X
autoinducer-2 production protein SP0340
hypothetical protein SP0341
glucan 1,6-alpha-glucosidase SP0342
IS1380-Spn1, transposase SP0343 X X X
IS630-Spn1, transposase Orf2 SP0344
IS630-Spn1, transposase Orf1 SP0345
capsular polysaccharide biosynthesis protein Cps4A SP0346
capsular polysaccharide biosynthesis protein Cps4B SP0347
capsular polysaccharide biosynthesis protein Cps4C SP0348
capsular polysaccharide biosynthesis protein Cps4D SP0349 X X X
capsular polysaccharide biosynthesis protein Cps4E SP0350 X X X
capsular polysaccharide biosynthesis protein Cps4F SP0351 X X X
capsular polysaccharide biosynthesis protein Cps4G SP0352 X X X
capsular polysaccharide biosynthesis protein Cps4H SP0353 X X X
hypothetical protein SP0354 X X X
hypothetical protein SP0355 X X X
O-antigen transporter RfbX, putative SP0356 X X X
UDP-N-acetylglucosamine-2-epimerase SP0357 X X X
capsular polysaccharide biosynthesis protein cps4J SP0358 X X X
capsular polysaccharide biosynthesis protein Cps4K SP0359 X X X
UDP-N-acetylglucosamine 2-epimerase SP0360 X X X
IS66 family element, Orf3, degenerate SP0362
transposase family protein, truncation SP0363 X X X
IS66 family element, Orf2, interruption SP0364 X
IS66 family element, Orf1, authentic frameshift SP0365 X X X
oligopeptide ABC transporter, oligopeptide-binding protein AliSP0366
hypothetical protein SP0367 X X X
cell wall surface anchor family protein, authentic frameshift SP0368 X X X
penicillin-binding protein 1A SP0369
recombination protein U SP0370
conserved hypothetical protein SP0371 X X X
conserved hypothetical protein SP0372
conserved hypothetical protein SP0373
hypothetical protein SP0374
6-phosphogluconate dehydrogenase, decarboxylating SP0375
DNA-binding response regulator SP0376
choline binding protein C SP0377
choline binding protein J SP0378
conserved hypothetical protein SP0379 X X X
hypothetical protein SP0380 X X X
mevalonate kinase SP0381
mevalonate diphosphate decarboxylase SP0382
phosphomevalonate kinase SP0383
FMN-dependent dehydrogenase family protein SP0384
conserved hypothetical protein SP0385
sensor histidine kinase, putative SP0386
DNA-binding response regulator SP0387
hypothetical protein, authentic frameshift SP0388
hypothetical protein SP0389
choline binding protein G SP0390
choline binding protein F SP0391
IS3-Spn1, transposase, degenerate SP0392 X
IS3-Spn1, hypothetical protein, authentic point mutation SP0393 X X X
PTS system, mannitol-specific IIBC components SP0394 X X X
transcriptional regulator, putative SP0395 X X X
PTS system, mannitol-specific IIA component SP0396 X X X
mannitol-1-phosphate 5-dehydrogenase SP0397 X X X
hypothetical protein SP0398 X X X
glutamine ABC transporter, ATP-binding protein, truncation SP0399 X X X
trigger factor SP0400
helicase, putative SP0401
signal peptidase I SP0402 X X
signal peptidase I SP0402 X
ribonuclease HIII SP0403
hypothetical protein SP0404
conserved hypothetical protein SP0405
MutS2 family protein SP0406
sodium:alanine symporter family protein SP0408
conserved hypothetical protein SP0409 X X X
exfoliative toxin, putative SP0410 X
seryl-tRNA synthetase SP0411
conserved hypothetical protein SP0412
aspartate kinase SP0413
enoyl-CoA hydratase/isomerase family protein SP0415
transcriptional regulator, MarR family SP0416
3-oxoacyl-(acyl-carrier-protein) synthase III SP0417
acyl carrier protein SP0418
enoyl-(acyl-carrier-protein) reductase SP0419
malonyl CoA-acyl carrier protein transacylase SP0420
3-oxoacyl-[acyl-carrier protein] reductase SP0421
3-oxoacyl-(acyl-carrier-protein) synthase II SP0422
acetyl-CoA carboxylase, bitoin carboxyl carrier protein SP0423
(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase SP0424
acetyl-CoA carboxylase, biotin carboxylase SP0425
acetyl-CoA carboxylase, carboxyl transferase subunit beta SP0426
acetyl-CoA carboxylase, carboxyl transferase subunit alpha SP0427
hypothetical protein SP0429 X X X
hypothetical protein SP0430 X
conserved domain protein SP0431 X X X
IS1167, transposase, interruption SP0432
N utilization substance protein B SP0433
conserved hypothetical protein SP0434
translation elongation factor P SP0435
glutamyl-tRNA(Gln) amidotransferase, B subunit SP0436 X X X
glutamyl-tRNA(Gln) amidotransferase, A subunit SP0437
glutamyl-tRNA(Gln) amidotransferase, C subunit SP0438
peptide chain release factor 3 SP0439
glycosyl transferase, degenerate SP0440 X
glycosyl transferase, degenerate SP0440
ribosomal protein L28 SP0441
conserved hypothetical protein SP0442
conserved hypothetical protein SP0443
acetolactate synthase, large subunit, biosynthetic type SP0445
acetolactate synthase, small subunit SP0446
ketol-acid reductoisomerase SP0447
hypothetical protein SP0448 X
hypothetical protein SP0449
threonine dehydratase SP0450
hypothetical protein SP0451
amino acid ABC transporter, ATP-binding protein SP0452
amino acid ABC transporter, amino acid-binding protein/permeasSP0453
hypothetical protein SP0454 X X X
hypothetical protein SP0455 X
transposase, IS116/IS110/IS902 family, degenerate SP0456
bacitracin resistance protein SP0457
DNA-damage inducible protein P SP0458
formate acetyltransferase SP0459
IS1167, transposase SP0460 X X X
transcriptional regulator, putative SP0461 X X X
cell wall surface anchor family protein SP0462 X X X
cell wall surface anchor family protein SP0463 X X X
cell wall surface anchor family protein SP0464 X X X
hypothetical protein SP0465 X X X
sortase, putative SP0466 X X X
sortase, putative SP0467 X X X
sortase, putative SP0468 X X X
IS1167, transposase, interruption SP0469
IS1167, transposase, interruption SP0469
hypothetical protein SP0470 X X X
conserved hypothetical protein SP0471 X
hypothetical protein SP0472 X X X
ROK family protein SP0473
PTS system, cellobiose-specific IIC component SP0474 X X X
hypothetical protein SP0475 X X X
PTS system, lactose-specific IIA component SP0476 X X X
6-phospho-beta-galactosidase SP0477 X
PTS system, lactose-specific IIBC components SP0478 X X X
potassium uptake protein, Trk family SP0479
potassium uptake protein, Trk family SP0480
conserved hypothetical protein SP0481
conserved hypothetical protein SP0482
ABC transporter, ATP-binding protein SP0483
conserved hypothetical protein SP0484 X
RNA methyltransferase, TrmH family SP0486 X X X
hypothetical protein SP0487 X
conserved hypothetical protein SP0488
PAP2 family protein SP0489
hypothetical protein SP0490
hypothetical protein SP0491 X
conserved domain protein SP0492 X X X
DNA-directed RNA polymerase, delta subunit, putative SP0493
CTP synthase SP0494
IS1380-Spn1, transposase SP0495 X X X
Na/Pi cotransporter II-related protein SP0496
endo-beta-N-acetylglucosaminidase, putative SP0498 X X X
phosphoglycerate kinase SP0499
conserved domain protein SP0500 X
transcriptional regulator, MerR family SP0501
glutamine synthetase, type I SP0502
hypothetical protein SP0503 X X X
type I restriction-modification system, S subunit, putative SP0505 X X
integrase/recombinase, phage integrase family SP0506 X
type I restriction-modification system, S subunit, putative SP0507 X
type I restriction-modification system, S subunit SP0508
type I restriction-modification system, M subunit SP0509
type I restriction-modification system, R subunit SP0510 X
hypothetical protein SP0511 X X X
hypothetical protein SP0512 X X X
hypothetical protein SP0513 X X X
hypothetical protein SP0514 X X X
heat-inducible transcription repressor HrcA SP0515
heat shock protein GrpE SP0516
dnaK protein SP0517
dnaJ protein SP0519
hypothetical protein SP0520
HIT family protein SP0521 X X X
ABC transporter, ATP-binding protein SP0522
ABC transporter, permease protein, putative SP0523
BlpT protein, fusion SP0524 X X X
blpS protein SP0525
response regulator BlpR SP0526 X X X
putative histidine kinase BlpH SP0527 X
transport protein BlpB SP0529 X X X
BlpC ABC transporter, ATP-binding protein, authentic frameshifSP0530 X
bacteriocin BlpI SP0531 X X X
bacteriocin BlpJ SP0532 X X X
bacteriocin BlpK SP0533
hypothetical protein SP0535 X X X
immunity protein BlpL SP0536 X X X
IS1381, transposase OrfA SP0537 X
IS1381, transposase OrfB SP0538
bacteriocin BlpM SP0539 X X X
blpN protein SP0540 X X X
bacteriocin BlpO SP0541 X
hypothetical protein SP0542 X X X
hypothetical protein SP0543 X X X
immunity protein BlpX SP0544 X X X
immunity protein BlpY SP0545 X X
BlpZ protein, fusion SP0546 X X X
conserved domain protein SP0547 X X X
hypothetical protein SP0548 X X X
conserved hypothetical protein SP0549
conserved hypothetical protein SP0550
conserved hypothetical protein SP0552
N utilization substance protein A SP0553 X
conserved hypothetical protein SP0554
ribosomal protein L7A family SP0555
translation initiation factor IF-2 SP0556
ribosome-binding factor A SP0557
conserved hypothetical protein SP0558 X X X
hypothetical protein SP0559 X
hypothetical protein SP0560 X X X
conserved domain protein SP0561 X
conserved hypothetical protein SP0562
hypothetical protein SP0563 X X X
hypothetical protein SP0564
conserved domain protein SP0565
acetyltransferase, GNAT family SP0566 X
conserved domain protein SP0567 X X X
valyl-tRNA synthetase SP0568
conserved domain protein SP0570 X X X
cell filamentation protein Fic-related protein SP0571 X
IS1167, transposase, degenerate SP0572
hypothetical protein SP0573 X X X
hypothetical protein SP0574 X X X
helicase, putative SP0575 X X X
transcription antiterminator Lict SP0576 X X X
PTS system, beta-glucosides-specific IIABC components SP0577 X X X
6-phospho-beta-glucosidase SP0578 X
phenylalanyl-tRNA synthetase, alpha subunit SP0579
acetyltransferase, GNAT family SP0580 X
phenylalanyl-tRNA synthetase, beta subunit SP0581
hypothetical protein SP0582
IS1239, transposase, putative, degenerate SP0583 X
transcriptional regulator, putative SP0584 X
5-methyltetrahydropteroyltriglutamate--homocysteine methyltranSP0585 X X X
5,10-methylenetetrahydrofolate reductase, putative SP0586 X X X
hypothetical protein SP0587 X X X
polyribonucleotide nucleotidyltransferase SP0588
serine acetyltransferase SP0589
acetyltransferase, GNAT family SP0590
cysteinyl-tRNA synthetase SP0591
conserved hypothetical protein SP0592
leucine-rich protein SP0593
hypothetical protein, fusion SP0594 X X X
hypothetical protein SP0595 X X X
hypothetical protein SP0596 X X X
group II intron, maturase, degenerate SP0597 X
group II intron, maturase, degenerate SP0597 X
hypothetical protein SP0598 X X X
transmembrane protein Vexp1 SP0599 X
ABC transporter, ATP-binding protein Vexp2 SP0600 X X X
transmembrane protein Vexp3 SP0601 X
DNA-binding response regulator VncR SP0603
sensor histidine kinase VncS SP0604
fructose-bisphosphate aldolase SP0605
oxidoreductase, putative SP0606
amino acid ABC transporter, permease protein SP0607 X
amino acid ABC transporter, permease protein SP0608 X
amino acid ABC transporter, amino acid-binding protein SP0609 X
amino acid ABC transporter, ATP-binding protein SP0610 X
single-stranded-DNA-specific exonuclease RecJ SP0611
metallo-beta-lactamase superfamily protein SP0613
tributyrin esterase SP0614
beta-lactam resistance factor SP0615
beta-lactam resistance factor SP0616
conserved domain protein SP0617
excinuclease ABC, subunit C SP0618
conserved hypothetical protein SP0619
amino acid ABC transporter, amino acid-binding protein, putatiSP0620 X
nitroreductase family protein SP0622
dipeptidase SP0623
conserved hypothetical protein SP0624
conserved hypothetical protein, authentic point mutation SP0625
branched-chain amino acid transport system II carrier protein SP0626 X X X
conserved hypothetical protein SP0627
HIT family protein SP0628
conserved hypothetical protein SP0629
ribosomal protein L11 SP0630
ribosomal protein L1 SP0631
group II intron, maturase, truncation SP0632 X
hypothetical protein SP0633 X X X
conserved domain protein SP0634 X X X
hypothetical protein SP0635
ABC transporter, ATP-binding protein SP0636
membrane protein SP0637 X
conserved hypothetical protein SP0638
hypothetical protein SP0639
hypothetical protein SP0640 X
serine protease, subtilase family SP0641
IS1167, transposase, truncation SP0642 X X
IS1167, transposase, truncation SP0642 X
transposase family protein, truncation SP0643 X
IS66 family element, Orf3, degenerate SP0644
PTS system IIA component, putative SP0645 X X X
PTS system, IIB component, putative SP0646 X X X
PTS system, IIC component, putative SP0647 X X X
beta-galactosidase SP0648 X X X
conserved hypothetical protein, degenerate SP0649 X X X
hypothetical protein SP0650 X
conserved hypothetical protein SP0651 X
conserved hypothetical protein SP0652
hypothetical protein SP0653 X X X
sodium/hydrogen exchanger family protein SP0655 X
hypothetical protein SP0656 X
ribonuclease BN, putative SP0657 X
cytochrome c-type biogenesis protein CcdA SP0658 X X
cytochrome c-type biogenesis protein CcdA SP0658 X X
thioredoxin family protein SP0659 X X
thioredoxin family protein SP0659 X X
peptide methionine sulfoxide reductase SP0660 X X X
DNA-binding response regulator SP0661 X
sensor histidine kinase, putative SP0662 X
conserved hypothetical protein SP0663
zinc metalloprotease ZmpB, putative SP0664 X X X
chorismate binding enzyme SP0665 X
conserved hypothetical protein SP0666 X X X
pneumococcal surface protein, putative SP0667
glucokinase SP0668
thymidylate synthase SP0669
hypothetical protein SP0670
tRNA isopentenylpyrophosphate transferase SP0671
GTP-binding protein HflX SP0672
hypothetical protein SP0673
metallo-beta-lactamase superfamily protein SP0674
oxidoreductase, short chain dehydrogenase/reductase family SP0675
transcriptional regulator, putative SP0676
conserved hypothetical protein SP0677
conserved hypothetical protein SP0678
hypothetical protein SP0679 X X X
ribosomal small subunit pseudouridine synthase A SP0680 X X X
elongation factor Tu family protein SP0681
hypothetical protein SP0682 X
conserved hypothetical protein SP0686 X
ABC transporter, ATP-binding protein SP0687 X X X
UDP-N-acetylmuramoylalanine--D-glutamate ligase SP0688
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophSP0689
cell division protein DivIB SP0690
hypothetical protein SP0691 X
hypothetical protein SP0692 X X X
conserved domain protein SP0694 X
HesA/MoeB/ThiF family protein SP0695 X
hypothetical protein SP0696 X X X
ABC transporter, ATP-binding protein, authentic point mutationSP0697 X X X
hypothetical protein SP0698 X X X
transposase, IS30 family, degenerate SP0700 X
orotidine 5-phosphate decarboxylase SP0701 X X X
orotate phosphoribosyltransferase PyrE SP0702 X
hypothetical protein SP0703 X
hypothetical protein SP0704 X X X
hypothetical protein SP0705 X
hypothetical protein SP0706 X X X
ABC transporter, ATP-binding protein SP0707 X
amino acid ABC transporter, amino acid-binding protein, authenSP0708 X X X
amino acid ABC transporter, ATP-binding protein SP0709 X X X
amino acid ABC transporter, permease protein SP0710 X
amino acid ABC transporter, permease protein SP0711 X X X
lactate oxidase, truncation SP0712
lysyl-tRNA synthetase SP0713
IS1380-Spn1, transposase SP0714 X X X
lactate oxidase SP0715
transcriptional regulator, putative SP0716
hydroxyethylthiazole kinase SP0717
thiamine-phosphate pyrophosphorylase SP0718 X X X
conserved hypothetical protein SP0719 X X X
ABC transporter, ATP-binding protein SP0720 X X X
conserved hypothetical protein SP0721 X X X
transcriptional activator TenA SP0722 X X X
conserved domain protein SP0723 X X X
hydroxyethylthiazole kinase, putative SP0724 X X X
thiamine-phosphate pyrophosphorylase SP0725 X X X
phosphomethylpyrimidine kinase SP0726 X X X
transcriptional repressor, putative SP0727 X X X
hypothetical protein SP0728
cation-transporting ATPase, E1-E2 family SP0729
pyruvate oxidase SP0730
conserved domain protein SP0731
transposase family protein, authentic frameshift SP0732 X X X
hypothetical protein SP0733 X X X
6-phospho-beta-glucosidase, truncation SP0735 X X X
mannose-6-phosphate isomerase SP0736
sodium-dependent transporter SP0737 X X X
conserved domain protein SP0738 X X X
transcriptional regulator, MerR family SP0739 X
MutT/nudix family protein SP0740 X
conserved hypothetical protein SP0741
conserved hypothetical protein SP0742
transcriptional regulator, TetR family SP0743 X
cytidine and deoxycytidylate deaminase family protein SP0744 X
uracil phosphoribosyltransferase SP0745
ATP-dependent Clp protease, proteolytic subunit SP0746
conserved hypothetical protein SP0748 X
branched-chain amino acid ABC transporter, amino acid-binding SP0749
branched-chain amino acid ABC transporter, permease protein SP0750
branched-chain amino acid ABC transporter, permease protein SP0751
branched-chain amino acid ABC transporter, ATP-binding proteinSP0752
branched-chain amino acid ABC transporter, ATP-binding proteinSP0753
acetoin utilization protein AcuB, putative SP0754 X X X
peptide chain release factor 2, authentic frameshift SP0755
cell division ABC transporter, ATP-binding protein FtsE SP0756
cell division ABC transporter, permease protein FtsX SP0757
PTS system, IIABC components SP0758 X
hypothetical protein SP0759 X X X
hypothetical protein SP0760 X X X
ATP-dependent RNA helicase, DEAD/DEAH box family SP0761 X
S-adenosylmethionine synthetase SP0762
hypothetical protein SP0763 X X X
dihydroorotate dehydrogenase A SP0764
conserved hypothetical protein SP0765
superoxide dismutase, manganese-dependent SP0766
conserved hypothetical protein SP0767
conserved hypothetical protein SP0768
VanZF-related protein SP0769
ABC transporter, ATP-binding protein SP0770
peptidyl-prolyl cis-trans isomerase, cyclophilin-type SP0771
hypothetical protein SP0772 X X X
hypothetical protein SP0774 X X X
ribosomal protein S16 SP0775
KH domain protein SP0776
hypothetical protein SP0777
16S rRNA processing protein RimM SP0778
tRNA (guanine-N1)-methyltransferase SP0779
ribonucleoside-diphosphate reductase, alpha subunit, truncatioSP0780
hypothetical protein SP0781
conserved hypothetical protein SP0782 X X X
conserved hypothetical protein SP0783
glutathione reductase SP0784
conserved hypothetical protein SP0785
ABC transporter, ATP-binding protein SP0786
conserved hypothetical protein SP0787
methionyl-tRNA synthetase SP0788
conserved hypothetical protein SP0789 X
conserved domain protein SP0790 X
oxidoreductase, aldo/keto reductase family SP0791
hypothetical protein SP0792
oxidoreductase, short chain dehydrogenase/reductase family SP0793
MutT/nudix family protein SP0794
PEP-utilizing enzymes family protein SP0795 X
conserved hypothetical protein SP0796 X
aminopeptidase N SP0797
DNA-binding response regulator CiaR SP0798
sensor histidine kinase CiaH SP0799
hypothetical protein SP0800
conserved hypothetical protein SP0801
DNA polymerase III, epsilon subunit/ATP-dependent helicase DinSP0802
rod shape-determining protein RodA, putative SP0803
4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesisSP0804
hydrolase, haloacid dehalogenase-like family SP0805
DNA gyrase subunit B SP0806
septation ring formation regulator EzrA, putative SP0807
hypothetical protein SP0810 X X X
transposase family protein SP0811 X X X
IS66 family element, Orf2, interruption SP0812
IS3-Spn1, hypothetical protein, authentic point mutation SP0813 X
IS3-Spn1, transposase, internal deletion SP0814 X X X
hypothetical protein SP0816
MutT/nudix family protein SP0817 X X X
IS630-Spn1, transposase Orf1 SP0818
IS630-Spn1, transposase Orf2 SP0819
ATP-dependent Clp protease, ATP-binding subunit ClpE SP0820
conserved hypothetical protein SP0822
amino acid ABC transporter, permease protein SP0823 X X X
amino acid ABC transporter, ATP-binding protein SP0824 X
methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolaSP0825
hypothetical protein SP0826 X X X
conserved hypothetical protein, authentic point mutation SP0827 X X X
ribose 5-phosphate isomerase SP0828
phosphopentomutase SP0829
hypothetical protein SP0830
purine nucleoside phosphorylase, family 2 SP0831
hypothetical protein SP0832 X
hypothetical protein SP0833
hemolysin-related protein SP0834
purine nucleoside phosphorylase, family 1 SP0835
IS1167, transposase SP0836
IS1167, transposase SP0836
DNA topology modulation protein FlaR, putative SP0837
ribosomal protein S20 SP0838
pantothenate kinase SP0839
hypothetical protein SP0840 X X X
conserved hypothetical protein SP0841
pyrimidine-nucleoside phosphorylase SP0842
deoxyribose-phosphate aldolase SP0843
cytidine deaminase SP0844
lipoprotein SP0845
sugar ABC transporter, ATP-binding protein SP0846
sugar ABC transporter, permease protein, putative SP0847
sugar ABC transporter, permease protein, putative SP0848
IS3-Spn1, hypothetical protein, degenerate SP0849 X X X
IS3-Spn1, transposase, authentic point mutation SP0850 X
conserved hypothetical protein SP0851 X
topoisomerase IV, subunit B SP0852 X
hypothetical protein SP0854 X X X
topoisomerase IV, subunit A SP0855 X
branched-chain amino acid aminotransferase SP0856
oligopeptide-binding protein, internal deletion, authentic poiSP0857
membrane protein, putative SP0858
membrane protein SP0859
pyrrolidone-carboxylate peptidase SP0860
hypothetical protein SP0861
ribosomal protein S1 SP0862
IS1167, transposase, degenerate SP0863
conserved hypothetical protein SP0864
DNA polymerase III, gamma and tau subunits SP0865
hypothetical protein SP0866
ABC transporter, ATP-binding protein SP0867
conserved hypothetical protein SP0868
aminotransferase, class-V SP0869
NifU family protein SP0870
conserved hypothetical protein SP0871
D-alanyl-D-alanine carboxypeptidase SP0872
membrane protein SP0873
lactose phosphotransferase system repressor SP0875
1-phosphofructokinase, putative SP0876
PTS system, fructose specific IIABC components SP0877 X
spoE family protein SP0878
hypothetical protein SP0879 X X
aminotransferase, class-V SP0880
thiazole biosynthesis protein ThiI SP0881
conserved hypothetical protein SP0882 X X X
hypothetical protein SP0883 X X X
hypothetical protein SP0884 X X X
hypothetical protein SP0885 X
type I restriction-modification system, M subunit, putative SP0886
type I restriction-modification system, S subunit, putative SP0887
hypothetical protein SP0888 X X X
hypothetical protein SP0889 X X X
integrase/recombinase, phage integrase family SP0890 X X X
type I restriction-modification system, S subunit, putative SP0891 X X X
type I restriction-modification system, R subunit, putative SP0892
transcriptional repressor, putative SP0893 X X X
X-pro dipeptidyl-peptidase SP0894 X X X
DNA polymerase III, alpha subunit SP0895 X
6-phosphofructokinase SP0896
pyruvate kinase SP0897
transcriptional repressor, degenerate SP0898 X
conserved hypothetical protein SP0899 X
IS1381, transposase OrfA, truncation SP0900 X X X
hypothetical protein SP0901 X
hypothetical protein SP0902 X X X
hypothetical protein SP0903 X X X
conserved hypothetical protein SP0904
conserved hypothetical protein SP0905
capsular polysaccharide biosynthesis protein, putative SP0907 X X X
transcriptional regulator, putative SP0908
conserved hypothetical protein SP0909 X
conserved hypothetical protein SP0910
hypothetical protein SP0911 X X X
ABC transporter, ATP-binding protein SP0912 X X X
ABC transporter, permease protein, putative SP0913 X X X
nodulin-related protein, truncation SP0914 X X X
IS1239, transposase, putative SP0915 X X X
lysine decarboxylase SP0916 X
pilin gene inverting-related protein SP0917
spermidine synthase SP0918
conserved hypothetical protein SP0919 X
carboxynorspermidine decarboxylase SP0920 X
conserved hypothetical protein SP0921
carbon-nitrogen hydrolase family protein SP0922
Cof family protein SP0923 X X X
hypothetical protein SP0924 X X X
conserved hypothetical protein SP0925 X
hypothetical protein SP0926 X X X
transcriptional regulator, LysR family SP0927
lipoprotein signal peptidase SP0928
ribosomal large subunit pseudouridine synthase D SP0929 X
choline binding protein E SP0930
glutamate 5-kinase SP0931
gamma-glutamyl phosphate reductase SP0932
pyrroline-5-carboxylate reductase SP0933 X
thymidylate kinase SP0935
DNA polymerase III, delta prime subunit SP0936
conserved hypothetical protein SP0937 X
tetrapyrrole methylase family protein SP0938
conserved hypothetical protein SP0939 X
replication initiator protein, truncation, authentic frameshifSP0940 X X X
IS1381, transposase OrfB SP0941
IS1381, transposase OrfA SP0942 X
Gid protein SP0943
uridylate kinase SP0944
ribosome recycling factor SP0945
conserved hypothetical protein SP0946 X X
conserved hypothetical protein SP0947 X
PhoH family protein SP0948
IS1515, transposase, authentic frameshift SP0949 X X X
acetyltransferase, GNAT family SP0950
conserved hypothetical protein SP0951
alanine dehydrogenase, authentic frameshift SP0952 X
acetyltransferase, GNAT family SP0953 X X X
competence protein CelA SP0954 X X X
competence protein CelB SP0955 X X X
hypothetical protein SP0956
ABC transporter, ATP-binding protein SP0957 X X X
hypothetical protein SP0958
translation initiation factor IF-3 SP0959
ribosomal protein L35 SP0960
ribosomal protein L20 SP0961
lactoylglutathione lyase SP0962
dihydroorotate dehydrogenase, electron transfer subunit SP0963
dihydroorotate dehydrogenase B SP0964
endo-beta-N-acetylglucosaminidase SP0965
adherence and virulence protein A SP0966
conserved hypothetical protein TIGR00043 SP0967
diacylglycerol kinase SP0968 X X X
GTP-binding protein Era SP0969
formamidopyrimidine-DNA glycosylase SP0970
kinase, putative SP0971
multi-drug resistance efflux pump SP0972
ribosomal protein L33 SP0973 X
preprotein translocase, SecG subunit, putative SP0974
exoribonuclease, VacB/Rnb family SP0975
SsrA-binding protein SP0976
tellurite resistance protein TehB SP0977 X X
tellurite resistance protein TehB SP0977 X
competence protein CoiA SP0978 X X X
oligoendopeptidase F SP0979
O-methyltransferase SP0980
protease maturation protein, putative SP0981
IS3-Spn1, hypothetical protein/transposase, internal deletion SP0982 X X X
IS630-Spn1, transposase Orf2, degenerate SP0983 X X X
phosphoglycerate mutase family protein SP0984 X
regulatory protein, putative SP0985 X
conserved hypothetical protein SP0986 X
hypothetical protein SP0987
UDP-N-acetylglucosamine pyrophosphorylase SP0988
MutT/nudix family protein SP0989
hypothetical protein SP0990
5-methylthioadenosine/S-adenosylhomocysteine nucleosidase SP0991
conserved hypothetical protein SP0992
exonuclease SP0993
hypothetical protein SP0994
IS630-Spn1, transposase Orf1 SP0995
IS630-Spn1, transposase Orf2, truncation SP0996
hypothetical protein SP0997 X X X
hypothetical protein SP0998 X X X
cytochrome c-type biogenesis protein CcdA SP0999 X X X
thioredoxin family protein SP1000
amino acid permease family protein SP1001
adhesion lipoprotein SP1002
conserved hypothetical protein SP1003
conserved hypothetical protein SP1004 X X X
conserved domain protein, degenerate SP1005 X X X
hypothetical protein SP1006 X X X
hypothetical protein SP1007 X X X
peptidase t SP1008
ferrochelatase SP1009 X X X
large conductance mechanosensitive channel protein MscL SP1010
GtrA family protein SP1011 X X X
conserved hypothetical protein SP1012 X
aspartate-semialdehyde dehydrogenase SP1013
dihydrodipicolinate synthase SP1014
IS1167, transposase, authentic frameshift SP1015
IS1167, transposase, authentic frameshift SP1015
thiophene and furan oxidation protein ThdF SP1016
4-oxalocrotonate tautomerase SP1017
thymidine kinase SP1018
acetyltransferase, GNAT family SP1019
peptide chain release factor 1 SP1020
HemK protein SP1021
Sua5/YciO/YrdC family protein SP1022
acetyltransferase, GNAT family SP1023
serine hydroxymethyltransferase SP1024
hypothetical protein SP1025 X
conserved hypothetical protein SP1026
conserved hypothetical protein SP1027
RNA methyltransferase, TrmA family SP1029
conserved hypothetical protein SP1030 X X X
iron-compound ABC transporter, iron compound-binding protein SP1032
iron-compound ABC transporter, permease protein SP1033 X
iron-compound ABC transporter, permease protein SP1034 X
iron-compound ABC transporter, ATP-binding protein SP1035 X
type II restriction endonuclease, putative SP1037 X X X
hypothetical protein SP1038 X X X
hypothetical protein SP1039 X X X
site-specific recombinase, resolvase family SP1040 X
hypothetical protein SP1041 X X X
hypothetical protein SP1042 X X X
hypothetical protein SP1043 X
hydrolase, putative SP1044 X
conserved hypothetical protein TIGR00147 SP1045
alpha amylase family protein, authentic point mutation SP1046 X X X
hypothetical protein SP1047 X X X
hypothetical protein SP1048 X X X
hypothetical protein SP1049 X X X
transcriptional regulator, putative SP1050 X X X
conserved hypothetical protein SP1051 X
phosphoesterase, putative SP1052 X
conserved domain protein SP1053 X
Tn5252, Orf 10 protein SP1054 X X X
Tn5252, Orf 9 protein SP1055 X X X
Tn5252, relaxase SP1056 X X X
transcriptional regulator PlcR, putative SP1057 X X X
hypothetical protein SP1058 X X X
hypothetical protein SP1059 X X X
hypothetical protein SP1060 X X X
protein kinase, putative SP1061 X X X
ABC transporter, ATP-binding protein SP1062 X X X
ABC-2 transporter, permease protein, putative SP1063 X X X
transposase, IS200 family SP1064 X X X
hypothetical protein SP1065 X X X
IS1381, transposase OrfA, truncation SP1066 X X X
cell division protein FtsW, putative SP1067
phosphoenolpyruvate carboxylase SP1068
conserved hypothetical protein SP1069 X
conserved hypothetical protein SP1070
ABC transporter, ATP-binding protein SP1071
DNA primase SP1072
RNA polymerase sigma-70 factor SP1073
conserved hypothetical protein SP1074
glycosyl transferase CpoA SP1075
glycosyl transferase, group 1 SP1076
conserved domain protein SP1077 X
hypothetical protein SP1078 X X X
GTP-binding protein, GTP1/Obg family SP1079
hypothetical protein SP1080 X
UDP-N-acetylglucosamine 1-carboxyvinyltransferase SP1081
acetyltransferase, GNAT family SP1082
conserved hypothetical protein SP1083
methionine aminopeptidase, type I SP1084
IS1381, transposase OrfA, authentic frameshift SP1085 X
IS1381, transposase OrfB SP1086
ATP-dependent DNA helicase PcrA SP1087
DNA repair protein RadC SP1088
glutamine amidotransferase, class I SP1089 X
conserved hypothetical protein SP1090
hypothetical protein SP1092 X
hypothetical protein SP1093 X
aminotransferase, class-V SP1094
ribose-phosphate pyrophosphokinase SP1095
conserved hypothetical protein SP1096 X X X
conserved hypothetical protein SP1097 X X
conserved hypothetical protein SP1098
ribosomal large subunit pseudouridine synthase, RluD subfamilySP1099
phosphate acetyltransferase SP1100
IS1167, transposase, degenerate SP1101
conserved hypothetical protein TIGR00103 SP1102 X
hypothetical protein SP1104
ribosomal protein L21 SP1105
conserved hypothetical protein SP1106
ribosomal protein L27 SP1107
hypothetical protein SP1108 X X X
hypothetical protein SP1109 X X X
macrolide-efflux protein SP1110
conserved hypothetical protein SP1111
degV family protein SP1112
DNA-binding protein HU SP1113
ABC transporter, ATP-binding protein SP1114 X
ABC transporter, ATP-binding protein SP1114 X
transcriptional regulator MutR, putative SP1115 X
transporter, putative SP1116 X
DNA ligase, NAD-dependent SP1117 X
pullulanase, putative SP1118
glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent SP1119 X
1,4-alpha-glucan branching enzyme SP1121 X X X
glucose-1-phosphate adenylyltransferase SP1122
glycogen biosynthesis protein GlgD SP1123 X
glycogen synthase SP1124 X
phosphoserine phosphatase SerB, degenerate SP1125 X X X
conserved hypothetical protein TIGR00045 SP1126 X X X
hypothetical protein SP1127 X
enolase SP1128
integrase/recombinase, phage integrase family SP1129 X X X
transcriptional regulator SP1130 X X X
transcriptional regulator, putative SP1131 X X X
hypothetical protein SP1132 X X X
hypothetical protein SP1133 X X X
hypothetical protein SP1134 X X X
hypothetical protein SP1135 X X X
conserved domain protein SP1136 X X X
GTP-binding protein, putative SP1137 X X X
hypothetical protein SP1138 X X X
hypothetical protein SP1139 X X X
hypothetical protein SP1140 X X X
hypothetical protein SP1141 X X X
hypothetical protein SP1142 X X X
conserved hypothetical protein SP1143 X X X
conserved hypothetical protein SP1144 X X X
hypothetical protein SP1145 X X X
hypothetical protein SP1146 X X X
integrase/recombinase, phage integrase family, truncation SP1147 X
IS630-Spn1, transposase Orf2 SP1148
IS630-Spn1, transposase Orf1 SP1149
exonuclease RexB SP1151 X
exonuclease RexA SP1152
hypothetical protein SP1153
immunoglobulin A1 protease SP1154 X X X
GTP-binding protein SP1155 X
ribonuclease HII SP1156
voltage-gated chloride channel family protein SP1157
integrase/recombinase, phage integrase family SP1159
lipoate-protein ligase, putative SP1160
acetoin dehydrogenase complex, E3 component, dihydrolipoamide SP1161 X X X
acetoin dehydrogenase complex, E2 component, dihydrolipoamide SP1162 X X X
acetoin dehydrogenase, E1 component, beta subunit, putative SP1163
acetoin dehydrogenase, E1 component, alpha subunit, putative SP1164
MATE efflux family protein SP1166
dihydroorotase, multifunctional complex type SP1167
mutator MutT protein SP1168 X
uracil-DNA glycosylase SP1169 X
hypothetical protein SP1170 X
hydrolase, haloacid dehalogenase-like family SP1171
hypothetical protein SP1172 X X X
conserved hypothetical protein SP1173 X X X
conserved domain protein SP1174
conserved domain protein SP1175
phosphoenolpyruvate-protein phosphotransferase SP1176
phosphocarrier protein HPr SP1177
NrdH-redoxin SP1178 X X
NrdH-redoxin SP1178 X X
ribonucleoside-diphosphate reductase 2, alpha subunit SP1179
ribonucleoside-diphosphate reductase 2, beta subunit SP1180
lactose phosphotransferase system repressor SP1182
hypothetical protein SP1183 X X X
6-phospho-beta-galactosidase SP1184 X
PTS system, lactose-specific IIBC components SP1185 X X X
PTS system, lactose-specific IIA component SP1186 X X X
transcription antiterminator LacT SP1187 X X X
hypothetical protein SP1189 X X X
tagatose 1,6-diphosphate aldolase SP1190 X X X
tagatose-6-phosphate kinase SP1191 X X X
galactose-6-phosphate isomerase, LacB subunit SP1192 X
galactose-6-phosphate isomerase, LacA subunit SP1193 X
lacX protein, truncation SP1194 X X X
IS1381, transposase OrfB SP1195
IS1381, transposase OrfA, authentic frameshift SP1196 X
conserved hypothetical protein SP1197 X X X
hypothetical protein SP1198 X X X
hypothetical protein SP1199 X X X
GTP-binding protein LepA SP1200
serine/threonine protein phosphatase SP1201 X X X
DNA repair protein RecN SP1202
transcriptional repressor, putative SP1203
hemolysin A, putative SP1204 X
geranyltranstransferase SP1205
exodeoxyribonuclease VII, small subunit SP1206
exodeoxyribonuclease VII, large subunit SP1207
uridine kinase SP1208
hypothetical protein SP1209 X X X
hypothetical protein SP1210 X
tRNA pseudouridine synthase B SP1212
conserved domain protein SP1213 X X X
transulfuration enzyme family protein, authentic point mutatioSP1214 X X X
transporter, FNT family, putative SP1215 X X X
hypothetical protein SP1216 X X X
conserved hypothetical protein SP1218
DNA gyrase subunit A SP1219
L-lactate dehydrogenase SP1220
type II restriction endonuclease, putative SP1221
type II restriction endonuclease, putative SP1222
conserved hypothetical protein SP1223 X
conserved domain protein SP1224 X
vicX protein SP1225
sensory box sensor histidine kinase SP1226
DNA-binding response regulator SP1227
A/G-specific adenine glycosylase SP1228
formate--tetrahydrofolate ligase SP1229
conserved hypothetical protein SP1230
flavoprotein SP1231
membrane protein SP1232 X
hypothetical protein SP1233 X
transcriptional regulator, biotin repressor family SP1234 X X X
MutT/nudix family protein SP1235 X
acetyltransferase, GNAT family SP1236 X X X
acetyltransferase, GNAT family SP1237 X X X
excinuclease ABC, subunit B SP1238
conserved hypothetical protein SP1240
amino acid ABC transporter, amino acid-binding protein/permeasSP1241
amino acid ABC transporter, ATP-binding protein SP1242
glucose-6-phosphate 1-dehydrogenase SP1243
signal recognition particle-docking protein FtsY SP1244
Cof family protein SP1245 X
Cof family protein SP1246
conserved hypothetical protein SP1247
ribonuclease III SP1248 X
conserved hypothetical protein SP1249
conserved domain protein SP1250 X X X
endonuclease, putative SP1251 X X X
hypothetical protein SP1252 X X X
hypothetical protein SP1254 X X X
3-isopropylmalate dehydratase, small subunit, putative SP1255 X
conserved hypothetical protein SP1256 X X X
3-isopropylmalate dehydrogenase, authentic point mutation SP1257 X
2-isopropylmalate synthase, putative SP1258
conserved hypothetical protein SP1259 X
copper homeostasis protein CutC SP1260
conserved hypothetical protein SP1261 X
IS1167, transposase SP1262
DNA topoisomerase I SP1263
conserved domain protein SP1264 X
DNA processing protein DprA, putative SP1266
licC protein SP1267
licB protein SP1268
choline kinase SP1269
alcohol dehydrogenase, zinc-containing SP1270
cytidine diphosphocholine pyrophosphorylase, putative SP1271
polysaccharide biosynthesis protein, putative SP1272
licD1 protein SP1273
licD2 protein SP1274 X
carbamoyl-phosphate synthase, large subunit SP1275
carbamoyl-phosphate synthase, small subunit SP1276
aspartate carbamoyltransferase SP1277
pyrimidine operon regulatory protein SP1278
endonuclease III SP1279
conserved hypothetical protein SP1280
hypothetical protein SP1281 X X X
ABC transporter, ATP-binding protein SP1282 X
heat shock protein HtpX SP1283
lemA protein SP1284
glucose-inhibited division protein B SP1285
uracil permease SP1286
signal recognition particle protein SP1287
conserved hypothetical protein SP1288 X
hypothetical protein SP1289 X
conserved hypothetical protein SP1290
Cof family protein SP1291 X
SAP domain protein SP1292 X X X
ribosomal protein L19 SP1293
crcB protein SP1294 X
crcB protein SP1295
chorismate mutase, putative SP1296
flavodoxin SP1297
DHH subfamily 1 protein SP1298
ribosomal protein L31 SP1299
hypothetical protein SP1300 X X X
transposase family protein, degenerate SP1301 X X X
conserved hypothetical protein SP1302 X
NADP-specific glutamate dehydrogenase SP1306
hypothetical protein SP1307 X
toxin secretion ATP-binding protein, truncation SP1308
IS1381, transposase OrfB, authentic frameshift SP1309 X
IS1381, transposase OrfA SP1310
IS66 family element, Orf3, degenerate SP1311
transposase family protein, degenerate SP1312 X
IS66 family element, Orf2, interruption SP1313 X
IS66 family element, Orf1 SP1314 X X X
v-type sodium ATP synthase, subunit D SP1315 X X X
v-type sodium ATP synthase, subunit B SP1316 X X X
v-type sodium ATP synthase, subunit A SP1317 X X X
v-type sodium ATP synthase, subunit G SP1318 X X X
v-type sodium ATP synthase, subunit C SP1319 X X X
v-type sodium ATP synthase, subunit E SP1320 X X X
v-type sodium ATP synthase, subunit K SP1321 X X X
v-type sodium ATP synthase, subunit I SP1322 X X X
hypothetical protein SP1323 X X X
ROK family protein SP1324 X X X
oxidoreductase, Gfo/Idh/MocA family SP1325 X X X
neuraminidase, putative SP1326 X X X
conserved hypothetical protein SP1327 X X X
sodium:solute symporter family protein SP1328 X X X
N-acetylneuraminate lyase SP1329 X X X
N-acetylmannosamine-6-P epimerase, putative SP1330 X X X
phosphosugar-binding transcriptional regulator, putative SP1331 X X X
conserved domain protein SP1332 X X X
hypothetical protein SP1333 X
conserved hypothetical protein SP1334 X X X
hypothetical protein SP1335 X X X
type II DNA modification methyltransferase Spn5252IP SP1336 X X X
IS1380-Spn1, transposase SP1337 X X X
hypothetical protein SP1338 X X X
hypothetical protein SP1340 X
ABC transporter, ATP-binding protein SP1341 X
toxin secretion ABC transporter, ATP-binding/permease protein SP1342 X
prolyl oligopeptidase family protein SP1343 X
conserved hypothetical protein SP1344 X X X
hypothetical protein SP1345 X
conserved hypothetical protein SP1346 X X X
hypothetical protein SP1347
conserved hypothetical protein SP1348 X X X
hypothetical protein SP1349 X X X
conserved domain protein SP1350 X X X
hypothetical protein SP1351 X X X
IS1380-Spn1, transposase SP1352 X X X
ribosomal protein L7/L12 SP1354
ribosomal protein L10 SP1355
Atz/Trz family protein SP1356
ABC transporter, ATP-binding/permease protein SP1357
ABC transporter, ATP-binding/permease protein SP1358
peptide methionine sulfoxide reductase SP1359
homoserine kinase SP1360
homoserine dehydrogenase SP1361
putative transcriptional regulator MecA SP1362
conserved domain protein SP1363
hypothetical protein SP1364 X X X
glycosyl transferase, family 2 SP1365
glycosyl transferase, group 1 SP1366
licD3 protein SP1367
psr protein SP1368
prephenate dehydratase SP1369
shikimate kinase SP1370
3-phosphoshikimate 1-carboxyvinyltransferase SP1371
conserved hypothetical protein SP1372
prephenate dehydrogenase SP1373
chorismate synthase SP1374
3-dehydroquinate synthase SP1375
shikimate 5-dehydrogenase SP1376
3-dehydroquinate dehydratase SP1377
conserved hypothetical protein SP1378
hypothetical protein SP1379 X X X
hypothetical protein SP1380 X
ABC transporter, ATP-binding protein SP1381 X X X
alpha-amylase SP1382 X X X
alanyl-tRNA synthetase SP1383
conserved hypothetical protein SP1384
hypothetical protein SP1385 X
spermidine/putrescine ABC transporter, spermidine/putrescine-bSP1386
spermidine/putrescine ABC transporter, permease protein SP1387
spermidine/putrescine ABC transporter, permease protein SP1388
spermidine/putrescine ABC transporter, ATP-binding protein SP1389
UDP-N-acetylenolpyruvoylglucosamine reductase SP1390
conserved hypothetical protein SP1391 X
alpha-acetolactate decarboxylase SP1392
conserved hypothetical protein SP1393
amino acid ABC transporter, amino acid-binding protein SP1394
phosphate transport system regulatory protein PhoU, putative SP1395
phosphate ABC transporter, ATP-binding protein, putative SP1396
phosphate ABC transporter, ATP-binding protein, putative SP1397
phosphate ABC transporter, permease protein, putative SP1398
phosphate ABC transporter, permease protein, putative SP1399
phosphate ABC transporter, phosphate-binding protein, putativeSP1400 X X
hypothetical protein SP1401
NOL1/NOP2/sun family protein SP1402 X
inositol monophosphatase family protein SP1403
conserved hypothetical protein SP1404
conserved hypothetical protein SP1405
hypothetical protein SP1406
hydrolase, haloacid dehalogenase-like family SP1407
acyl-ACP thioesterase, putative SP1408
oxygen-independent coproporphyrinogen III oxidase, putative SP1409
conserved hypothetical protein SP1410
conserved hypothetical protein SP1411
prolipoprotein diacylglyceryl transferase SP1412
Hpr(Ser) kinase/phosphatase SP1413
ribosomal protein S21 SP1414
ribosomal protein S21 SP1414 X X X
glucosamine-6-phosphate isomerase SP1415
S-adenosylmethionine:tRNA ribosyltransferase-isomerase SP1416
pspC protein, degenerate SP1417 X
IS1380-Spn1, transposase SP1418 X X X
acetyltransferase, GNAT family SP1419
NH(3)-dependent NAD(+) synthetase SP1420 X X
conserved hypothetical protein SP1421
hypothetical protein SP1422 X X X
transcriptional repressor, putative SP1423 X X X
hypothetical protein SP1424 X X X
ABC transporter, ATP-binding protein SP1426 X
peptidase, U32 family SP1427
conserved hypothetical protein SP1428 X
peptidase, U32 family SP1429
type II restriction endonuclease, putative, authentic point muSP1430
type II DNA modification methyltransferase, putative SP1431 X
hypothetical protein SP1432 X X X
transcriptional regulator, araC family SP1433
ABC transporter, ATP-binding/permease protein SP1434 X X X
ABC transporter, ATP-binding protein SP1435 X X X
hypothetical protein SP1436 X X X
conserved domain protein SP1437 X X X
ABC transporter, ATP-binding protein SP1438 X X X
IS1380-Spn1, transposase SP1439 X X X
ABC transporter, ATP-binding protein, fragment SP1440 X X X
IS66 family element, Orf3, degenerate SP1441 X
IS66 family element, Orf2 SP1442 X
IS66 family element, Orf1 SP1443 X X X
IS1167, transposase SP1444
GMP synthase SP1445
transcriptional regulator, GntR family SP1446 X X X
membrane protein SP1447 X
conserved hypothetical protein SP1448
cppA protein SP1449
platelet activating factor, putative SP1450 X X X
Cof family protein SP1451 X
hypothetical protein SP1452 X
conserved domain protein SP1453 X
hypothetical protein SP1454 X X X
hypothetical protein SP1455 X X X
polypeptide deformylase SP1456
spoU rRNA methylase family protein SP1457
thioredoxin reductase SP1458
hypothetical protein SP1459 X X X
amino acid ABC transporter, ATP-binding protein SP1460
amino acid ABC transporter, permease protein SP1461
conserved hypothetical protein SP1462
methylated-DNA--protein-cysteine S-methyltransferase SP1463
acetyltransferase, GNAT family SP1464
hypothetical protein SP1465
hemolysin SP1466
conserved hypothetical protein SP1467
pyridoxine biosynthesis protein SP1468
NADH oxidase SP1469
thiamine biosynthesis protein ApbE, putative SP1470 X X X
oxidoreductase, putative SP1471 X
oxidoreductase, putative SP1472 X X X
conserved hypothetical protein SP1473 X
glycyl-tRNA synthetase, beta subunit SP1474
glycyl-tRNA synthetase, alpha subunit SP1475
hypothetical protein SP1476
hypothetical protein SP1476 X X X
hypothetical protein SP1477
oxidoreductase, aldo/keto reductase family SP1478
peptidoglycan N-acetylglucosamine deacetylase A SP1479
hypothetical protein SP1480 X X
oxidoreductase, Gfo/Idh/MocA family SP1482
ATP-dependent RNA helicase, DEAD/DEAH box family SP1483
transposase family protein, authentic frameshift SP1484 X
IS3-Spn1, transposase SP1485 X X X
IS3-Spn1, hypothetical protein, degenerate SP1486 X X X
hypothetical protein SP1487 X
hypothetical protein SP1488 X
translation elongation factor Tu SP1489
glycerol uptake facilitator protein, putative SP1491
cell wall surface anchor family protein SP1492 X X X
hypothetical protein SP1493 X X X
hypothetical protein SP1494
hypothetical protein SP1495 X X X
transposase, IS630-Spn1 related, Orf2 SP1496 X X X
transposase, IS630-Spn1 related, Orf1, authentic frameshift SP1497 X X X
phosphoglucomutase SP1498
bacterocin transport accessory protein SP1499
amino acid ABC transporter, amino acid-binding protein SP1500
amino acid ABC transporter, ATP-binding protein SP1501
amino acid ABC transporter, permease protein SP1502
IS1380-Spn1, transposase SP1503 X X X
TPR domain protein SP1504
membrane protein SP1505
conserved hypothetical protein SP1506
ATP synthase F1, epsilon subunit SP1507
ATP synthase F1, beta subunit SP1508
ATP synthase F1, gamma subunit SP1509
ATP synthase F1, alpha subunit SP1510
ATP synthase F1, delta subunit SP1511
ATP synthase F0, B subunit SP1512 X X
ATP synthase F0, A subunit SP1513
ATP synthase F0, C subunit SP1514
IS1239, transposase, putative, degenerate SP1515 X X X
acetyltransferase, GNAT family SP1516
transcription elongation factor GreA SP1517
conserved hypothetical protein SP1518
acetyltransferase, GNAT family SP1519 X
acetyltransferase, GNAT family SP1520
UDP-N-acetylmuramate--alanine ligase SP1521
conserved domain protein SP1522
Snf2 family protein SP1523
aminotransferase, class II SP1524 X
transulfuration enzyme family protein SP1525
ABC transporter, ATP-binding protein authentic frameshift SP1526 X
oligopeptide ABC transporter, oligopeptide-binding protein AliSP1527
polysaccharide biosynthesis protein, putative SP1529
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate liSP1530
hypothetical protein SP1531 X
conserved domain protein, authentic frameshift SP1532 X
conserved domain protein SP1533 X
inorganic pyrophosphatase, manganese-dependent SP1534
conserved hypothetical protein SP1535
conserved hypothetical protein SP1536
general stress protein 13, putative SP1537
cof family protein/peptidyl-prolyl cis-trans isomerase, cyclopSP1538
ribosomal protein S18 SP1539
single-strand binding protein SP1540
ribosomal protein S6 SP1541
asparaginyl-tRNA synthetase SP1542
conserved hypothetical protein, authentic point mutation SP1543
aspartate aminotransferase SP1544
conserved hypothetical protein SP1545
conserved domain protein SP1546
conserved hypothetical protein SP1547
hypothetical protein SP1548
polypeptide deformylase SP1549
glutathione S-transferase family protein SP1550
cation-transporting ATPase, E1-E2 family SP1551
cation efflux family protein SP1552
ABC transporter, ATP-binding protein SP1553
polyA polymerase family protein SP1554 X X
polyA polymerase family protein SP1554 X
dihydrodipicolinate reductase SP1555
hypothetical protein SP1556 X X X
degV family protein SP1557
hypothetical protein SP1558
phosphoglucomutase/phosphomannomutase family protein SP1559
conserved hypothetical protein SP1560
conserved hypothetical protein SP1561
hypothetical protein SP1562 X X X
pyridine nucleotide-disulphide oxidoreductase family protein SP1563
conserved hypothetical protein SP1564
conserved hypothetical protein SP1565
conserved hypothetical protein SP1566
endoribonuclease L-PSP SP1567
GTP-binding protein SP1568
ATP-dependent Clp protease, ATP-binding subunit ClpX SP1569
hypothetical protein SP1570 X
dihydrofolate reductase SP1571
non-heme iron-containing ferritin SP1572
lysozyme SP1573
triosephosphate isomerase SP1574
conserved hypothetical protein SP1575
homoserine O-succinyltransferase SP1576
adenine phosphoribosyltransferase SP1577
methyltransferase, putative SP1578
sugar ABC transporter, ATP-binding protein SP1580
hypothetical protein SP1581 X X X
IS1167, transposase SP1582
isochorismatase family protein SP1583
transcriptional regulator, putative SP1584
ATP-dependent RNA helicase, putative SP1586
oxalate:formate antiporter SP1587
oxidoreductase, pyridine nucleotide-disulfide, class I SP1588
oxidoreductase, pyridine nucleotide-disulfide, class I SP1588 X X X
Mur ligase family protein SP1589
conserved hypothetical protein SP1590
proline dipeptidase SP1591
conserved domain protein SP1592 X X X
IS3-Spn1, transposase, authentic point mutation SP1593 X X X
IS3-Spn1,
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