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Section III
Figure S1
Figure S1. Characteristics
of AML cases clustered in Figure 1, and
associated similarity plot. (A) The
dendogram generated in Figure 1 is reproduced
in this figure with the sample number, genetic
lesion and FAB morphology indicated next
to each case. (B) To further assess
the relationship both within and between
leukemia subtypes, the expression data for
all of the cases were analyzed by pair wise
comparisons. The data is displayed using
a two-dimensional plot in which similarities
are plotted using a scale that is based
on Pearson correlation coefficients calculated
for pair wise comparisons using the expression
data for the 16,608 genes that passed the
variation filter. The degree of similarity
between cases is displayed using the blue
color-scale at bottom of figure. The leukemia
subtypes are organized identically to their
distribution in the dendogram shown in panel A and
are color coded as noted in the Key.
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