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AML1
Table of Contents
Section
I. Patient Datasets
Table S1.
Diagnostic AML characteristics
Table S2.
Cytogenetics Summary
Table S3.
Adult diagnostic AML characteristics
Table S4.
Additional T-ALL characteristics
Section II. Methods
Table S5.
Summary of filtered probe sets
Table S6.
MLL
-PTD primers
Additional Statistical Methods
Section III. Genetic Subtype Discriminating Genes
Figure S1.
Unsupervised Heirarchical clustering
Figure S2.
Heirarchical clustering with class discriminating genes
Table S7.
Top 100 probe sets selected by SAM for t(8;21)[
AML1-ETO
]
Table S8.
Top 100 probe sets selected by SAM for t(15;17) [
PML-RARa
]
Table S9.
Top 63 probe sets selected by SAM for inv(16) [
CBFb-MYH11
]
Table S10.
Top 100 probe sets selected by SAM for
MLL
chimeric fusion genes
Table S11.
Top 100 probe sets selected by SAM for FAB-M7
Table S12.
Top 100 probe sets selected by SAM for CBF leukemias (whole dataset)
Section IV.
MLL
in combined ALL and AML dataset
Table S13.
Top 100 probe sets selected by SAM for
MLL
chimeric fusions irrespective of blast lineage (whole dataset)
Table S14.
Class discriminating genes for cases with an
MLL
chimeric fusion gene that show uniform high expression, irrespective of blast lineage
Section V. Outcome Analysis
Expression profiles as a predictor of time to relapse
Evaluation of relapse genes identified by Yagi et. al. on this dataset
Table S15.
Probe sets most strongly associated with time to progression or relapse in the training set
Table S16
Patient outcome data used in training set
Table S17
Patient outcome data used in test set
Section VI. Additional Reference
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